Dynamic VHost with mod_rewrite

.htaccess

# Mod Rewrite
RewriteEngine on
RewriteBase /

# Top Level Domains
RewriteCond %{HTTP_HOST} ^(?:.*?)([^.]+\.[^.]+)(?::80)?$ [NC]
RewriteCond %{REQUEST_URI} !^/domains
RewriteCond %{DOCUMENT_ROOT}/domains/%1 -d
RewriteRule ^(.*) /domains/%1/$1 [L]

# Subdomains
RewriteCond %{HTTP_HOST} ^(?:.*?)([^.]+)\.([^.]+\.[^.]+)(?::80)?$ [NC]
RewriteCond %{REQUEST_URI} !^/subdomains
RewriteCond %{DOCUMENT_ROOT}/subdomains/%2/%1 -d
RewriteRule ^(.*) /subdomains/%2/%1/$1 [L]