gistfile1.py

srcdir = "."
blddir = "build"

def set_options(opt):
  opt.tool_options("compiler_cxx")

def configure(conf):
  conf.check_tool("compiler_cxx")
  conf.check_tool("node_addon")
  conf.find_program('node', var='NODE', mandatory=True)
  if conf.check_cc(header_name="sys/inotify.h"):
    conf.check_cc(header_name="sys/inotify.h", function_name="inotify_init")

def build(bld):
  obj = bld.new_task_gen("cxx", "shlib", "node_addon")
  obj.target = "node-inotify"
  obj.source = bld.path.ant_glob('**/*.cc')

gistfile2.txt

camilo@macbooksito:~/Development/node-inotify$ node-waf clean configure build 
'clean' finished successfully (0.012s)
Checking for program g++ or c++          : /usr/bin/g++ 
Checking for program cpp                 : /usr/bin/cpp 
Checking for program ar                  : /usr/bin/ar 
Checking for program ranlib              : /usr/bin/ranlib 
Checking for g++                         : ok  
Checking for node prefix                 : ok /usr/local 
Checking for program node                : /usr/local/bin/node 
Checking for header sys/inotify.h        : not found 
'configure' finished successfully (0.036s)
Waf: Entering directory `/home/camilo/Development/node-inotify/build'
[1/3] cxx: src/node_inotify.cc -> build/default/src/node_inotify_1.o
[2/3] cxx: src/bindings.cc -> build/default/src/bindings_1.o
[3/3] cxx_link: build/default/src/node_inotify_1.o build/default/src/bindings_1.o -> build/default/src/node-inotify.node
Waf: Leaving directory `/home/camilo/Development/node-inotify/build'
'build' finished successfully (0.427s)

gistfile3.txt

camilo@macbooksito:~/Development/node-inotify$ file /usr/include/sys/inotify.h 
/usr/include/sys/inotify.h: ASCII C program text