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Using Unsupervised Learning to infer SNPs whose allelic expression is "hyper-variable" across samples: https://nbviewer.jupyter.org/gist/petermchale/c5e21f746fda65d8b379de88f224ac41
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Excellent resource for Bayesian Optimization:
"Taking the Human Out of the Loop: A Review of Bayesian Optimization"
https://ieeexplore.ieee.org/document/7352306