AES67 (an open standard for high quality audio over IP) is becoming mainstream in the world of broadcast and professional audio industries, however there is a very limited amount of open source software available to interoperate with it. As a result we are often just replacing XLRs with Ethernet, without taking advantage of the possibilites the software give. While Virtual Soundcards enable some of this, native network implementations would allow greater flexibility.
This is my wishlist of things that would help change that. Hopefully one day it can be turned into a AES67 Awesome List.
As open source has resulted in very rapid evolution of the web, I believe the same is possible for professional/broadcast audio.
It is possible that some of this already exists and I just havn't found it yet. Please add a comment below if you know of something!