The is a plist config for Zabbix agent daemon on Mac OS X 10.11

com.zabbix.zabbix_agentd.plist

<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE plist PUBLIC "-//Apple//DTD PLIST 1.0//EN" "http://www.apple.com/DTDs/PropertyList-1.0.dtd">
<plist version="1.0">
<dict>
	<key>Label</key>
	<string>com.zabbix.zabbix_agentd</string>
	<key>RunAtLoad</key>
	<true/>
	<key>KeepAlive</key>
	<dict>
		<key>SuccessfulExit</key>
		<false/>
	</dict>
	<key>ProgramArguments</key>
	<array>
    <string>/usr/local/sbin/zabbix_agentd</string>
		<string>-c</string>
		<string>/usr/local/Cellar/zabbix/2.4.6/etc/zabbix_agentd.conf</string>
	</array>
</dict>
</plist>

refs:

• osx - Can’t launch daemon with launchctl in Yosemite - Super User