manage.py + wsgi.py

manage.py

#!/usr/bin/env python
import os
import site
import sys
sys.dont_write_bytecode = True  # don't write .pyc files
sys.argv[0] = os.path.abspath(__file__)  # show full path in ps and top
sys.path.append(os.path.dirname(__file__))
site.addsitedir('/path/to/virtenv/lib/python2.7/site-packages')
os.environ['DJANGO_SETTINGS_MODULE'] = 'demo.settings'

if __name__ == '__main__':
    from django.core.management import execute_from_command_line

    execute_from_command_line(sys.argv)
else:  # wsgi
    from django.core.wsgi import get_wsgi_application
    application = get_wsgi_application()