A simple example to set and get ClickLockState

ClickLock.cs

static bool GetClickClock()
{
    const uint getMouseCl = 0x101E;

    bool res = true;
    uint time = 0;
    if(!PInvoke.SystemParametersInfo(getMouseCl, time, ref res, 0))
    {
        throw new Win32Exception();
    }
    return res;
}

static void SetClickClock(bool value)
{
    const uint setMouseCL = 0x101F;
    if (!PInvoke.SystemParametersInfo(setMouseCL, 0, value, 0))
    {
        throw new Win32Exception();
    }
}

public class PInvoke
{
    [DllImport("user32.dll", SetLastError = true)]
    [return: MarshalAs(UnmanagedType.Bool)]
    public static extern bool SystemParametersInfo(uint uiAction, uint uiParam , ref bool pvParam, uint fWinIni);

    [DllImport("user32.dll", SetLastError = true)]
    [return: MarshalAs(UnmanagedType.Bool)]
    public static extern bool SystemParametersInfo(uint uiAction, uint uiParam, bool pvParam, uint fWinIni);
}