Sample of using the Eto cross-platform GUI framework (https://github.com/picoe/Eto/) with F# (on windows)

Eto sample script

#r @"packages\Eto.Forms.1.3.0\lib\net40\Eto.dll"
#r @"packages\Eto.Platform.Windows.1.3.0\lib\net40\Eto.Platform.Windows.dll"

open System
open Eto.Forms
open Eto.Drawing


let MyEtoForm() = 
    let form = new Form(Title = "My Eto Form", ClientSize = new Size(400, 350))
    // DynamicLayout is the typical layout to use but you can also use TableLayout or PixelLayout
    let layout = new DynamicLayout()

    layout.BeginHorizontal() |> ignore

    layout.Add(null) |> ignore
    layout.Add(new Label(Text = "Hello World!")) |> ignore
    layout.Add(null) |> ignore

    layout.EndHorizontal()

    // scrollable gives you a scrolling region
    form.Content <- new Scrollable(Content = layout)

    // your commands!
    let clickMe = new Command(MenuText = "Click Me!", ShowLabel = true, ToolBarText = "Click Me!")
    clickMe.Executed.Add (fun e -> MessageBox.Show(form, "I was clicked!") |> ignore)

    let quitAction = new Command(MenuText = "Quit", Shortcut = (Application.Instance.CommonModifier ||| Keys.Q)) 
    quitAction.Executed.Add(fun e -> Application.Instance.Quit())


    // create menu & get standard menu items (e.g. needed for OS X)
    let menu = new MenuBar()
    Application.Instance.CreateStandardMenu(menu.Items)
            
    // add commands to the menu
    let myMenu = menu.Items.GetSubmenu("&File")
    myMenu.Items.Add(clickMe, 500)
    myMenu.Items.AddSeparator(500)
    myMenu.Items.Add(quitAction, 1000)
            
    menu.Items.Trim()
    form.Menu <- menu

    // create toolbar			
    let toolbar = new ToolBar()
    toolbar.Items.Add(clickMe)
    form.ToolBar <- toolbar
    form

let app = new Application()

let MainForm = MyEtoForm()
MainForm.Show()