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pythonReadGTFlocal
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from collections import defaultdict | |
import gzip | |
import pandas as pd | |
import re | |
GTF_HEADER = ['seqname', 'source', 'feature', 'start', 'end', 'score', | |
'strand', 'frame'] | |
R_SEMICOLON = re.compile(r'\s*;\s*') | |
R_COMMA = re.compile(r'\s*,\s*') | |
R_KEYVALUE = re.compile(r'(\s+|\s*=\s*)') | |
def dataframefromGTF(filename): | |
"""Open an optionally gzipped GTF file and return a pandas.DataFrame. | |
""" | |
# Each column is a list stored as a value in this dict. | |
result = defaultdict(list) | |
for i, line in enumerate(getGTFlines(filename)): | |
for key in line.keys(): | |
# This key has not been seen yet, so set it to None for all | |
# previous lines. | |
if key not in result: | |
result[key] = [None] * i | |
# Ensure this row has some value for each column. | |
for key in result.keys(): | |
result[key].append(line.get(key, None)) | |
return pd.DataFrame(result) | |
def getGTFlines(filename): | |
"""Open an optionally gzipped GTF file and generate a dict for each line. | |
""" | |
fn_open = gzip.open if filename.endswith('.gz') else open | |
with fn_open(filename) as fh: | |
for line in fh: | |
if line.startswith('#'): | |
continue | |
else: | |
yield parseGTFline(line) | |
def parseGTFline(line): | |
"""Parse a single GTF line and return a dict. | |
""" | |
result = {} | |
fields = line.rstrip().split('\t') | |
for i, col in enumerate(GTF_HEADER): | |
result[col] = _get_value(fields[i]) | |
# INFO field consists of "key1=value;key2=value;...". | |
infos = [x for x in re.split(R_SEMICOLON, fields[8]) if x.strip()] | |
for i, info in enumerate(infos, 1): | |
# It should be key="value". | |
try: | |
key, _, value = re.split(R_KEYVALUE, info, 1) | |
# But sometimes it is just "value". | |
except ValueError: | |
key = 'INFO{}'.format(i) | |
value = info | |
# Ignore the field if there is no value. | |
if value: | |
result[key] = _get_value(value) | |
return result | |
def _get_value(value): | |
if not value: | |
return None | |
# Strip double and single quotes. | |
value = value.strip('"\'') | |
# Return a list if the value has a comma. | |
if ',' in value: | |
value = re.split(R_COMMA, value) | |
# These values are equivalent to None. | |
elif value in ['', '.', 'NA']: | |
return None | |
return value |
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