This script will build python-2.7.x on a centos 6.x box. Tested on vagrant.

build_python_rpm.sh

# This works on vagrant rather well particularly with the passwordless sudo
# Tested on a Centos 6.5 box file
# Thanks to https://github.com/pingviini/rhel6-rpmbuild for
# specfile and install logic


# Set this to the version of python you want to build.
# As of this writing 2.7.6 is the latest
PYVER="2.7.6"

# Define builddir
RPMDIR=$HOME/rpmbuild

# RPM dependencies
sudo yum -y groupinstall "Development Tools"
sudo yum -y install kernel-devel rpmdevtools rpmlint rpm-build
sudo yum -y install bzip2-devel db4-devel expat-devel
sudo yum install autoconf bzip2 bzip2-devel db4-devel expat-devel \
    findutils gcc-c++ glibc-devel make openssl-devel pkgconfig readline-devel \
    sqlite-devel tar zlib-devel

# Create the rpmbuild trees
rpmdev-setuptree

# Grab the source for the python version defined above
cd $RPMDIR/SOURCES
if [ ! -e Python-${PYVER}.tgz ]; then
    wget http://www.python.org/ftp/python/${PYVER}/Python-${PYVER}.tgz
fi


# Gen the spec file
cat << EOF > $RPMDIR/SPECS/python27.spec

%define _topdir %(echo `cd ..; pwd`)
%define binsuffix 27
%define pybasever 2.7
%define version ${PYVER}
%define name python
%define release 1
%define _prefix /usr/local

Name: %{name}%{binsuffix}
Version: %{version}
Release: %{release}
Summary: An interpreted, interactive, object-oriented programming language.
Group: Development/Languages
Source0: http://www.python.org/ftp/python/%{version}/Python-%{version}.tgz

License: PSF
BuildRoot: %(mktemp -ud %{_tmppath}/%{name}-%{version}-%{release}-XXXXXX)

AutoReq: no
Provides: python(abi) = %{pybasever}

BuildRequires: autoconf
BuildRequires: bzip2
BuildRequires: bzip2-devel
BuildRequires: db4-devel
BuildRequires: expat-devel
BuildRequires: findutils
BuildRequires: gcc-c++
BuildRequires: glibc-devel
BuildRequires: make
BuildRequires: openssl-devel
BuildRequires: pkgconfig
BuildRequires: readline-devel
BuildRequires: sqlite-devel
BuildRequires: tar
BuildRequires: zlib-devel

%description
Python is an interpreted, interactive, object-oriented programming
language.  It incorporates modules, exceptions, dynamic typing, very high
level dynamic data types, and classes. Python combines remarkable power
with very clear syntax. It has interfaces to many system calls and
libraries, as well as to various window systems, and is extensible in C or
C++. It is also usable as an extension language for applications that need
a programmable interface.  Finally, Python is portable: it runs on many
brands of UNIX, on PCs under Windows, MS-DOS, and OS/2, and on the
Mac.

%package devel
Summary: The libraries and header files needed for Python extension development.
Requires: %{name} = %{version}-%{release}
Group: Development/Libraries

%description devel
The Python programming language's interpreter can be extended with
dynamically loaded extensions and can be embedded in other programs.
This package contains the header files and libraries needed to do
these types of tasks.

Install python-devel if you want to develop Python extensions.  The
python package will also need to be installed.  You'll probably also
want to install the python-docs package, which contains Python
documentation.

%prep
%setup -n Python-%{version}


%build
%configure \
	--enable-ipv6 \
	--enable-unicode=ucs4 \
	--enable-shared \
	--with-system-ffi \
	--with-system-expat \
	--prefix=%{_prefix}
%{__make} %{?_smp_mflags}


%install
[ -d $RPM_BUILD_ROOT ] && rm -fr $RPM_BUILD_ROOT

%{__make} altinstall DESTDIR=$RPM_BUILD_ROOT
%{__rm} -f $RPM_BUILD_ROOT%{_prefix}/bin/python{,2}
%{__rm} -f $RPM_BUILD_ROOT%{_prefix}/bin/python{,2}-config
%{__rm} -f $RPM_BUILD_ROOT%{_prefix}/bin/2to3
%{__rm} -f $RPM_BUILD_ROOT%{_prefix}/bin/idle
%{__rm} -f $RPM_BUILD_ROOT%{_prefix}/bin/pydoc
%{__rm} -f $RPM_BUILD_ROOT%{_prefix}/bin/smtpd.py
%{__rm} -rf $RPM_BUILD_ROOT%{_libdir}/pkgconfig/
%{__ln_s} %{_libdir}/python2.7/config $RPM_BUILD_ROOT%{_prefix}/lib/python2.7/config
%{__ln_s} %{_libdir}/python2.7/lib-dynload $RPM_BUILD_ROOT%{_prefix}/lib/python2.7/lib-dynload

mkdir -p $RPM_BUILD_ROOT/etc/ld.so.conf.d
touch $RPM_BUILD_ROOT/etc/ld.so.conf.d/python27.conf
echo "/usr/local/lib64" > $RPM_BUILD_ROOT/etc/ld.so.conf.d/python27.conf

%post -p /sbin/ldconfig

%postun -p /sbin/ldconfig


%clean
%{__rm} -rf $RPM_BUILD_ROOT


%files
%defattr(-,root,root,-)
%{_prefix}/lib/python2.7/*
%{_libdir}/python2.7/lib-dynload/*
%{_libdir}/libpython2.7.so*
%{_bindir}/python2.7*
%config(noreplace) /etc/ld.so.conf.d/python27.conf

%doc
%{_mandir}/*/*

%files devel
%defattr(-,root,root,-)
%{_prefix}/include/python2.7/*
%{_libdir}/python2.7/config/*

%changelog
* Sat Oct 26 2013 Jukka Ojaniemi <jukka.ojaniemi@gmail.com> - 2.7.5-1
- Initial RPM release
EOF

# PROFIT!!!
cd $RPMDIR/SPECS
QA_RPATHS=$[ 0x0001|0x0010 ] rpmbuild -bb python27.spec

# PTL