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Trying to write a genomic library in Rust

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Trying to write a genomic library in Rust
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@rxaviers
rxaviers / gist:7360908
Last active May 8, 2024 23:25
Complete list of github markdown emoji markup

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@jimbojsb
jimbojsb / gist:1630790
Created January 18, 2012 03:52
Code highlighting for Keynote presentations

Step 0:

Get Homebrew installed on your mac if you don't already have it

Step 1:

Install highlight. "brew install highlight". (This brings down Lua and Boost as well)

Step 2:

@elowy01
elowy01 / BCFtools cheat sheet
Last active May 7, 2024 16:51
BCFtools cheat sheet
*bcftools filter
*Filter variants per region (in this example, print out only variants mapped to chr1 and chr2)
qbcftools filter -r1,2 ALL.chip.omni_broad_sanger_combined.20140818.snps.genotypes.hg38.vcf.gz
*printing out info for only 2 samples:
bcftools view -s NA20818,NA20819 filename.vcf.gz
*printing stats only for variants passing the filter:
bcftools view -f PASS filename.vcf.gz
@yossorion
yossorion / what-i-wish-id-known-about-equity-before-joining-a-unicorn.md
Last active April 7, 2024 22:55
What I Wish I'd Known About Equity Before Joining A Unicorn

What I Wish I'd Known About Equity Before Joining A Unicorn

Disclaimer: This piece is written anonymously. The names of a few particular companies are mentioned, but as common examples only.

This is a short write-up on things that I wish I'd known and considered before joining a private company (aka startup, aka unicorn in some cases). I'm not trying to make the case that you should never join a private company, but the power imbalance between founder and employee is extreme, and that potential candidates would

@alimanfoo
alimanfoo / find_runs.py
Created November 5, 2017 23:53
Find runs of consecutive items in a numpy array.
import numpy as np
def find_runs(x):
"""Find runs of consecutive items in an array."""
# ensure array
x = np.asanyarray(x)
if x.ndim != 1:
raise ValueError('only 1D array supported')
@PoisonAlien
PoisonAlien / readBam.C
Last active November 9, 2023 21:21
reading bam files in C using htslib
#include <stdio.h>
#include <string.h>
#include <stdlib.h>
#include <htslib/sam.h>
int main(int argc, char *argv[]){
samFile *fp_in = hts_open(argv[1],"r"); //open bam file
bam_hdr_t *bamHdr = sam_hdr_read(fp_in); //read header
bam1_t *aln = bam_init1(); //initialize an alignment
@GaelVaroquaux
GaelVaroquaux / 00README.rst
Last active September 15, 2023 03:58
Copy-less bindings of C-generated arrays with Cython

Cython example of exposing C-computed arrays in Python without data copies

The goal of this example is to show how an existing C codebase for numerical computing (here c_code.c) can be wrapped in Cython to be exposed in Python.

The meat of the example is that the data is allocated in C, but exposed in Python without a copy using the PyArray_SimpleNewFromData numpy

@levand
levand / data-modeling.md
Last active May 19, 2023 16:38
Advice about data modeling in Clojure

Since it has come up a few times, I thought I’d write up some of the basic ideas around domain modeling in Clojure, and how they relate to keyword names and Specs. Firmly grasping these concepts will help us all write code that is simpler, cleaner, and easier to understand.

Clojure is a data-oriented language: we’re all familiar with maps, vectors, sets, keywords, etc. However, while data is good, not all data is equally good. It’s still possible to write “bad” data in Clojure.

“Good” data is well defined and easy to read; there is never any ambiguity about what a given data structure represents. Messy data has inconsistent structure, and overloaded keys that can mean different things in different contexts. Good data represents domain entities and a logical model; bad data represents whatever was convenient for the programmer at a given moment. Good data stands on its own, and can be reasoned about without any other knowledge of the codebase; bad data is deeply and tightly coupled to specific generating and

@Integralist
Integralist / Let Destructuring.md
Last active February 13, 2023 19:35
Clojure destructuring using `let` (which allows local storage inside of a function, we would say a local "variable" but that would be misleading because all data is immutable in Clojure)

In Clojure you can apply destructuring within either a let binding list; function parameter list or even a macro.

A simple example would be:

(def coords [5 7]) ; define a symbol "coords" that points to a vector [5 7]
(let [[x y] coords] (println "x:" x "y:" y))
; => x: 5 y: 7