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#!/usr/bin/env python2.7 | |
### On SNPsnap | |
#!/bin/env python | |
#source /opt/rh/python27/enable | |
#---> gives Python 2.7.5 (where as Broad Dotkit python is Python 2.7.1) | |
import os | |
import sys | |
import collections |
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#!/usr/bin/env python | |
import os | |
import sys | |
import pandas as pd | |
import numpy as np | |
import pyranges as pr | |
import argparse |
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def table(region, gwas_minus_region, total_gwas): | |
pos_cols = "Chromosome Start End".split() | |
total_region = len(region.drop_duplicates(pos_cols)) | |
tp = region.groupby("Trait").size() | |
fp = (tp - total_region).abs() | |
fn = gwas_minus_region.groupby("Trait").size() | |
tn = ((fn + tp + fp) - total_gwas).abs() |
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from scipy.stats import gaussian_kde | |
import numpy as np | |
import pandas as pd | |
df = pd.read_table(f, sep="\t") | |
values = df.CorrelationSum.sort_values() | |
gk = gaussian_kde(values) |
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➜ head ~/Downloads/CEU/CEU-22-final.txt | |
Position(bp) Rate(cM/Mb) Map(cM) Filtered | |
16489239 0.0 0.0 1 | |
16494187 0.0 0.0 1 | |
16504399 0.0 0.0 1 | |
16855618 0.0 0.0 1 | |
16869887 0.0 0.0 1 | |
16872459 0.0 0.0 1 | |
16890307 0.0 0.0 1 | |
16923693 0.0 0.0 1 |
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index1 = 0 | |
index2 = 0 | |
while index1 < len(posin): | |
pos = posin[index1] | |
rs = rsin[index1] | |
if pos == mappos[index2]: | |
#the 1000 Genomes site was genotyped as part of the map | |
results.append((rs, pos, mapgpos[index2])) | |
index1 = index1 + 1 |
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#!/usr/bin/env python3 | |
import sys, os, gzip, math | |
import numpy as np | |
# calculate Wen/Stephens shrinkage LD estimate | |
gmapfile = gzip.open(sys.argv[1]) # genetic map | |
indfile = open(sys.argv[2]) #list of individuals | |
# NE = 11418.0 | |
NE = float(sys.argv[3]) |
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def calc_diag_lean(self, out_fname, out_delim, dynamic_delete=True): | |
if dynamic_delete == False: | |
raise Exception('Error: Conversion has been run in lean mode, but with dynamically=False.') | |
self.dynamic_delete = dynamic_delete | |
flat.print_log_msg('Start') |
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#!/usr/bin/env python3 | |
import ldetect.baselib.flat_file_consts as cnst | |
import ldetect.baselib.flat_file as flat | |
import ldetect.baselib.binary_search as binsrch | |
import sys | |
import os.path | |
import math | |
import bisect |
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# from . import flat_file_consts as cnst | |
import sys | |
import csv | |
import gzip | |
import time | |
import math | |
import bisect | |
def get_final_partitions(input_config, name, snp_first, snp_last): |