Program.cs

var builder = WebApplication.CreateBuilder(args);
builder.Services.AddSingleton<BigCacheConsumer>();
builder.Services.AddSingleton<SmallCacheConsumer>();
builder.Services.AddKeyedSingleton<ICache, BigCache>("big");
builder.Services.AddKeyedSingleton<ICache, SmallCache>("small");
var app = builder.Build();
app.MapGet("/big", (BigCacheConsumer data) => data.GetData());
app.MapGet("/small", (SmallCacheConsumer data) => data.GetData());
app.Run();
class BigCacheConsumer([FromKeyedServices("big")] ICache cache)
{
    public object? GetData() => cache.Get("data");
}

class SmallCacheConsumer(IServiceProvider serviceProvider)
{
    public object? GetData() => serviceProvider.GetRequiredKeyedService<ICache>("small").Get("data");
}

public interface ICache
{
    object Get(string key);
}

public class BigCache : ICache
{
    public object Get(string key) => $"Resolving {key} from big cache.";
}

public class SmallCache : ICache
{
    public object Get(string key) => $"Resolving {key} from small cache.";
}