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This guide applies in general to all distributions that don't fully support Crossover or are unable to install all the packages that MS Office 2016 requires (e.g. you wouldn't want to layer all of them in Kinoite/Silverblue).

Prerequisite: You have bought a license for MS Office 2016 and for Codeweavers Crossover. Also you have the installer for MS Office 2016 downloaded already.

1. Install distrobox:

rpm-ostree install distrobox then reboot to apply changes.

2. Create a new distrobox container. This should be one of the officially supported distributions for Crossover (e.g. Debian, Fedora, Ubuntu). In this example I'll go with Debian Sid because it's rolling so you won't ever have to think about upgrading your container distro to the next version.

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How to install the Mullvad VPN app in Fedora Atomic Desktop (Kinoite, Silverblue etc.)

Enter these commands:

sudo -s
cd /etc/yum.repos.d/
wget https://repository.mullvad.net/rpm/stable/mullvad.repo
rpm-ostree install mullvad-vpn
systemctl reboot

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Step by step guide: How to install Microsoft Office 2016 in any Linux distribution

There are multiple options how to install MS Office on Linux.

VM-based - Integrate Windows apps running in a Windows VM as native-looking in Linux

1. Winapps, based on KVM, QEMU, Virt-Manager, and FreeRDP. Still actively maintained (getting Github commits).
2. Cassowary, based on KVM, QEMU, Virt-Manager, and FreeRDP. Has a helpful GUI and apparently can auto-suspend the VM when no Windows app is in use. Last release in Feb 2022 and seems to be abandoned.

The VM-based options means can run Office 2021 or Office 365 including all apps, but for me it was quite buggy and when I encounterd some (FreeRDP-related?) bug in both Winapps and Cassowary that meant I could only start Excel with an external screen plugged in, I gave up. bug