Created
April 25, 2023 11:09
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Genes vs Top Level Phenotypes Dataset
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| [ | |
| { | |
| "marker_accession_id": "MGI:101766", | |
| "marker_symbol": "Ryk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0006203", "mp_term_name": "eye hemorrhage" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101766", | |
| "marker_symbol": "Ryk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101769", | |
| "marker_symbol": "Mcl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101786", | |
| "marker_symbol": "Mtf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101857", | |
| "marker_symbol": "Usp15", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101857", | |
| "marker_symbol": "Usp15", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101857", | |
| "marker_symbol": "Usp15", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101876", | |
| "marker_symbol": "Tead1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101876", | |
| "marker_symbol": "Tead1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101876", | |
| "marker_symbol": "Tead1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101932", | |
| "marker_symbol": "Cpe", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Indirect Calorimetry", | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002797", "mp_term_name": "increased thigmotaxis" }, | |
| { | |
| "mp_term_id": "MP:0001488", | |
| "mp_term_name": "increased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002757", | |
| "mp_term_name": "decreased vertical activity" | |
| }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001392", | |
| "mp_term_name": "abnormal locomotor behavior" | |
| }, | |
| { "mp_term_id": "MP:0011940", "mp_term_name": "decreased food intake" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101932", | |
| "marker_symbol": "Cpe", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102465", | |
| "marker_symbol": "Tex2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102666", | |
| "marker_symbol": "Ppp5c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102722", | |
| "marker_symbol": "Pcnt", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102722", | |
| "marker_symbol": "Pcnt", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102780", | |
| "marker_symbol": "Six1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102780", | |
| "marker_symbol": "Six1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102805", | |
| "marker_symbol": "Entpd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Fasted Clinical Chemistry", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003019", | |
| "mp_term_name": "increased circulating chloride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002702", | |
| "mp_term_name": "decreased circulating free fatty acids level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005633", | |
| "mp_term_name": "increased circulating sodium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003442", | |
| "mp_term_name": "decreased circulating glycerol level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102853", | |
| "marker_symbol": "Elk4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry", "Fasted Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000183", | |
| "mp_term_name": "decreased circulating LDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005633", | |
| "mp_term_name": "increased circulating sodium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005634", | |
| "mp_term_name": "decreased circulating sodium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003442", | |
| "mp_term_name": "decreased circulating glycerol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002944", | |
| "mp_term_name": "increased lactate dehydrogenase level" | |
| } | |
| ], | |
| "phenotype_count": 11 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102853", | |
| "marker_symbol": "Elk4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Slit Lamp", "Indirect ophthalmoscopy"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102889", | |
| "marker_symbol": "Vcan", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0006203", "mp_term_name": "eye hemorrhage" }, | |
| { "mp_term_id": "MP:0000269", "mp_term_name": "abnormal heart looping" }, | |
| { | |
| "mp_term_id": "MP:0003229", | |
| "mp_term_name": "abnormal vitelline vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102944", | |
| "marker_symbol": "Ube2b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103201", | |
| "marker_symbol": "Aqp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103222", | |
| "marker_symbol": "Zbtb16", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103222", | |
| "marker_symbol": "Zbtb16", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103222", | |
| "marker_symbol": "Zbtb16", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103239", | |
| "marker_symbol": "Tfap4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Electrocardiogram (ECG)" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103239", | |
| "marker_symbol": "Tfap4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003050", | |
| "mp_term_name": "abnormal sacral vertebrae morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003049", | |
| "mp_term_name": "abnormal lumbar vertebrae morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103253", | |
| "marker_symbol": "Cyb561", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011496", "mp_term_name": "abnormal head size" }, | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104294", | |
| "marker_symbol": "Tyro3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104294", | |
| "marker_symbol": "Tyro3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104327", | |
| "marker_symbol": "Nog", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104327", | |
| "marker_symbol": "Nog", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001614", | |
| "mp_term_name": "abnormal blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0001914", "mp_term_name": "hemorrhage" }, | |
| { | |
| "mp_term_id": "MP:0003229", | |
| "mp_term_name": "abnormal vitelline vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104510", | |
| "marker_symbol": "Myo7a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005633", | |
| "mp_term_name": "increased circulating sodium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005565", | |
| "mp_term_name": "increased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104510", | |
| "marker_symbol": "Myo7a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["DEXA", "Body Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" }, | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104510", | |
| "marker_symbol": "Myo7a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002896", | |
| "mp_term_name": "abnormal bone mineralization" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104565", | |
| "marker_symbol": "Cdkn1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104565", | |
| "marker_symbol": "Cdkn1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104606", | |
| "marker_symbol": "Rab34", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5", | |
| "Heart Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { | |
| "mp_term_id": "MP:0003385", | |
| "mp_term_name": "abnormal body wall morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104606", | |
| "marker_symbol": "Rab34", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104606", | |
| "marker_symbol": "Rab34", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104630", | |
| "marker_symbol": "Wars", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104633", | |
| "marker_symbol": "Tle4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104634", | |
| "marker_symbol": "Tle3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104637", | |
| "marker_symbol": "Tgfbr3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104637", | |
| "marker_symbol": "Tgfbr3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104659", | |
| "marker_symbol": "Dll1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Food efficiency (GMC)", | |
| "Grip Strength (GMC)", | |
| "Shirpa (GMC)", | |
| "Holeboard (GMC)", | |
| "Spontaneous breathing (GMC)", | |
| "Bodyweight (GMC)" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104659", | |
| "marker_symbol": "Dll1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Spontaneous breathing (GMC)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005586", "mp_term_name": "decreased tidal volume" }, | |
| { | |
| "mp_term_id": "MP:0002337", | |
| "mp_term_name": "abnormal whole-body plethysmography" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104659", | |
| "marker_symbol": "Dll1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["ERG (Electroretinogram) (GMC)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005551", | |
| "mp_term_name": "abnormal eye electrophysiology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104663", | |
| "marker_symbol": "Lep", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "Echo", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002834", "mp_term_name": "decreased heart weight" }, | |
| { | |
| "mp_term_id": "MP:0011951", | |
| "mp_term_name": "increased cardiac stroke volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010392", | |
| "mp_term_name": "prolonged QRS complex duration" | |
| }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104663", | |
| "marker_symbol": "Lep", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104663", | |
| "marker_symbol": "Lep", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104669", | |
| "marker_symbol": "Man2a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "Echo"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003394", | |
| "mp_term_name": "increased cardiac output" | |
| }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104669", | |
| "marker_symbol": "Man2a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104723", | |
| "marker_symbol": "Fgf9", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104723", | |
| "marker_symbol": "Fgf9", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104725", | |
| "marker_symbol": "Atn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000223", | |
| "mp_term_name": "decreased monocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104725", | |
| "marker_symbol": "Atn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104749", | |
| "marker_symbol": "Osm", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Plasma Chemistry", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002702", | |
| "mp_term_name": "decreased circulating free fatty acids level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104749", | |
| "marker_symbol": "Osm", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104785", | |
| "marker_symbol": "Myo6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104976", | |
| "marker_symbol": "Ddx6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005568", | |
| "mp_term_name": "increased circulating total protein level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104976", | |
| "marker_symbol": "Ddx6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104993", | |
| "marker_symbol": "Lepr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104993", | |
| "marker_symbol": "Lepr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104993", | |
| "marker_symbol": "Lepr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { | |
| "mp_term_id": "MP:0001392", | |
| "mp_term_name": "abnormal locomotor behavior" | |
| }, | |
| { "mp_term_id": "MP:0001512", "mp_term_name": "trunk curl" }, | |
| { | |
| "mp_term_id": "MP:0001523", | |
| "mp_term_name": "impaired righting response" | |
| }, | |
| { "mp_term_id": "MP:0000745", "mp_term_name": "tremors" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0001406", "mp_term_name": "abnormal gait" }, | |
| { "mp_term_id": "MP:0001513", "mp_term_name": "limb grasping" }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104993", | |
| "marker_symbol": "Lepr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105089", | |
| "marker_symbol": "Hsd17b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011874", "mp_term_name": "enlarged urinary bladder" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105089", | |
| "marker_symbol": "Hsd17b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| }, | |
| { "mp_term_id": "MP:0011874", "mp_term_name": "enlarged urinary bladder" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105089", | |
| "marker_symbol": "Hsd17b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0000642", "mp_term_name": "enlarged adrenal glands" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105089", | |
| "marker_symbol": "Hsd17b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105917", | |
| "marker_symbol": "Fer", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105917", | |
| "marker_symbol": "Fer", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105917", | |
| "marker_symbol": "Fer", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106091", | |
| "marker_symbol": "Cyp7a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106209", | |
| "marker_symbol": "Hells", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Fasted Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000183", | |
| "mp_term_name": "decreased circulating LDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106209", | |
| "marker_symbol": "Hells", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Modified SHIRPA"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001406", "mp_term_name": "abnormal gait" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106211", | |
| "marker_symbol": "Cdc42", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106227", | |
| "marker_symbol": "Capza1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Light-Dark Test"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106604", | |
| "marker_symbol": "Gpld1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106913", | |
| "marker_symbol": "Abi2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107159", | |
| "marker_symbol": "Hmx2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107191", | |
| "marker_symbol": "Bmpr1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107191", | |
| "marker_symbol": "Bmpr1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107191", | |
| "marker_symbol": "Bmpr1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Fertility of Homozygous Knock-out Mice" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107363", | |
| "marker_symbol": "Stxbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107363", | |
| "marker_symbol": "Stxbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107363", | |
| "marker_symbol": "Stxbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107374", | |
| "marker_symbol": "Pitx1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000572", | |
| "mp_term_name": "abnormal autopod morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000558", | |
| "mp_term_name": "abnormal tibia morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000559", | |
| "mp_term_name": "abnormal femur morphology" | |
| }, | |
| { "mp_term_id": "MP:0004083", "mp_term_name": "polysyndactyly" }, | |
| { "mp_term_id": "MP:0008730", "mp_term_name": "fused phalanges" }, | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107403", | |
| "marker_symbol": "Clk1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Indirect ophthalmoscopy"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107474", | |
| "marker_symbol": "Cd38", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107484", | |
| "marker_symbol": "Rgl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107484", | |
| "marker_symbol": "Rgl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107484", | |
| "marker_symbol": "Rgl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107489", | |
| "marker_symbol": "Phex", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000198", | |
| "mp_term_name": "decreased circulating phosphate level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008805", | |
| "mp_term_name": "decreased circulating amylase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005566", | |
| "mp_term_name": "decreased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107511", | |
| "marker_symbol": "Art1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107577", | |
| "marker_symbol": "Wbp1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011239", "mp_term_name": "abnormal skin coloration" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107690", | |
| "marker_symbol": "Zfp462", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107716", | |
| "marker_symbol": "Myo10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0006243", | |
| "mp_term_name": "impaired pupillary reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001413", | |
| "mp_term_name": "abnormal response to new environment" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107731", | |
| "marker_symbol": "Dnah2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107731", | |
| "marker_symbol": "Dnah2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Fertility of Homozygous Knock-out Mice" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107792", | |
| "marker_symbol": "Lhx5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107792", | |
| "marker_symbol": "Lhx5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107823", | |
| "marker_symbol": "Ctsk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107899", | |
| "marker_symbol": "Cd36", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0006203", "mp_term_name": "eye hemorrhage" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:108077", | |
| "marker_symbol": "Nptn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:108426", | |
| "marker_symbol": "Kif1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005641", | |
| "mp_term_name": "increased mean corpuscular hemoglobin concentration" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:108519", | |
| "marker_symbol": "Meis3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:108519", | |
| "marker_symbol": "Meis3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0013129", "mp_term_name": "abnormal tooth color" }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109128", | |
| "marker_symbol": "Hnf4a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011964", | |
| "mp_term_name": "increased total retina thickness" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109185", | |
| "marker_symbol": "Ccn3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109185", | |
| "marker_symbol": "Ccn3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109249", | |
| "marker_symbol": "Adamts1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109249", | |
| "marker_symbol": "Adamts1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001404", "mp_term_name": "no spontaneous movement" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109249", | |
| "marker_symbol": "Adamts1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109320", | |
| "marker_symbol": "Mmp15", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109320", | |
| "marker_symbol": "Mmp15", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000467", | |
| "mp_term_name": "abnormal esophagus morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109331", | |
| "marker_symbol": "Nxn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5", | |
| "X-ray" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011495", "mp_term_name": "abnormal head shape" }, | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109336", | |
| "marker_symbol": "Etv6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109495", | |
| "marker_symbol": "Nfil3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000494", | |
| "mp_term_name": "abnormal cecum morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109514", | |
| "marker_symbol": "Cstb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109514", | |
| "marker_symbol": "Cstb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002574", | |
| "mp_term_name": "increased vertical activity" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109526", | |
| "marker_symbol": "Trpc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000550", | |
| "mp_term_name": "abnormal forelimb morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109526", | |
| "marker_symbol": "Trpc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109529", | |
| "marker_symbol": "Dpf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109563", | |
| "marker_symbol": "Cxcr4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004258", "mp_term_name": "abnormal placenta size" }, | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109617", | |
| "marker_symbol": "Barx2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002111", "mp_term_name": "abnormal tail morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109617", | |
| "marker_symbol": "Barx2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005287", "mp_term_name": "narrow eye opening" }, | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { "mp_term_id": "MP:0005542", "mp_term_name": "corneal vascularization" }, | |
| { "mp_term_id": "MP:0005176", "mp_term_name": "eyelids fail to open" }, | |
| { | |
| "mp_term_id": "MP:0001340", | |
| "mp_term_name": "abnormal eyelid morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109617", | |
| "marker_symbol": "Barx2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096391", | |
| "marker_symbol": "Nrxn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013278", | |
| "mp_term_name": "decreased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008806", | |
| "mp_term_name": "increased circulating amylase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002966", | |
| "mp_term_name": "decreased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096566", | |
| "marker_symbol": "Pias2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Insulin Blood Level"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002079", | |
| "mp_term_name": "increased circulating insulin level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096566", | |
| "marker_symbol": "Pias2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "Bodyweight (GMC)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096575", | |
| "marker_symbol": "Tex261", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010088", | |
| "mp_term_name": "decreased circulating fructosamine level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000183", | |
| "mp_term_name": "decreased circulating LDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096875", | |
| "marker_symbol": "Wdfy3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098240", | |
| "marker_symbol": "Kif16b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098264", | |
| "marker_symbol": "Kif13a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098274", | |
| "marker_symbol": "Cyp27b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098658", | |
| "marker_symbol": "Stag1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009552", | |
| "mp_term_name": "urinary bladder obstruction" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098658", | |
| "marker_symbol": "Stag1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098687", | |
| "marker_symbol": "Aak1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098727", | |
| "marker_symbol": "Trappc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009552", | |
| "mp_term_name": "urinary bladder obstruction" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098727", | |
| "marker_symbol": "Trappc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098727", | |
| "marker_symbol": "Trappc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098802", | |
| "marker_symbol": "Cdk12", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1099809", | |
| "marker_symbol": "Fgf10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100846", | |
| "marker_symbol": "Med1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Placenta E12.5", | |
| "Gross Morphology Embryo E12.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004258", "mp_term_name": "abnormal placenta size" }, | |
| { "mp_term_id": "MP:0001722", "mp_term_name": "pale yolk sac" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100883", | |
| "marker_symbol": "Celsr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Modified SHIRPA"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001486", "mp_term_name": "abnormal startle reflex" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100883", | |
| "marker_symbol": "Celsr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Slit Lamp"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100883", | |
| "marker_symbol": "Celsr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100883", | |
| "marker_symbol": "Celsr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1194883", | |
| "marker_symbol": "Crx", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011874", | |
| "mp_term_name": "enlarged urinary bladder" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000538", | |
| "mp_term_name": "abnormal urinary bladder morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1194883", | |
| "marker_symbol": "Crx", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000706", "mp_term_name": "small thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1196458", | |
| "marker_symbol": "Scarb2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1196625", | |
| "marker_symbol": "Fzd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1197514", | |
| "marker_symbol": "Pole2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1197514", | |
| "marker_symbol": "Pole2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1201414", | |
| "marker_symbol": "Cer1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1201414", | |
| "marker_symbol": "Cer1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1201679", | |
| "marker_symbol": "Cxadr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1202301", | |
| "marker_symbol": "Itch", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1202301", | |
| "marker_symbol": "Itch", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000467", | |
| "mp_term_name": "abnormal esophagus morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1202713", | |
| "marker_symbol": "Rhag", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1202875", | |
| "marker_symbol": "Btf3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011874", "mp_term_name": "enlarged urinary bladder" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1202875", | |
| "marker_symbol": "Btf3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001415", | |
| "mp_term_name": "increased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1202882", | |
| "marker_symbol": "Rhd", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001191", "mp_term_name": "abnormal skin condition" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1261819", | |
| "marker_symbol": "Dnmt3b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1261820", | |
| "marker_symbol": "Cand1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { "mp_term_id": "MP:0009342", "mp_term_name": "enlarged gallbladder" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1261820", | |
| "marker_symbol": "Cand1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1261820", | |
| "marker_symbol": "Cand1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1270862", | |
| "marker_symbol": "Axin2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0009263", "mp_term_name": "abnormal eyelid fusion" }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1276533", | |
| "marker_symbol": "Ncoa2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277096", | |
| "marker_symbol": "Ptp4a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277117", | |
| "marker_symbol": "Ptp4a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277117", | |
| "marker_symbol": "Ptp4a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277957", | |
| "marker_symbol": "Kcnn4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000601", "mp_term_name": "small liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277957", | |
| "marker_symbol": "Kcnn4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" }, | |
| { "mp_term_id": "MP:0000706", "mp_term_name": "small thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277957", | |
| "marker_symbol": "Kcnn4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000495", | |
| "mp_term_name": "abnormal colon morphology" | |
| }, | |
| { "mp_term_id": "MP:0009476", "mp_term_name": "enlarged cecum" }, | |
| { | |
| "mp_term_id": "MP:0000492", | |
| "mp_term_name": "abnormal rectum morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277957", | |
| "marker_symbol": "Kcnn4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Fear Conditioning", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0020421", | |
| "mp_term_name": "increased freezing behavior" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289184", | |
| "marker_symbol": "Setd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289184", | |
| "marker_symbol": "Setd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289184", | |
| "marker_symbol": "Setd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003900", "mp_term_name": "shortened QT interval" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289184", | |
| "marker_symbol": "Setd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289192", | |
| "marker_symbol": "Fbxo36", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Echo"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002953", "mp_term_name": "thick ventricular wall" }, | |
| { | |
| "mp_term_id": "MP:0003921", | |
| "mp_term_name": "abnormal heart left ventricle morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289192", | |
| "marker_symbol": "Fbxo36", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008935", | |
| "mp_term_name": "decreased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005641", | |
| "mp_term_name": "increased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0000223", | |
| "mp_term_name": "decreased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289298", | |
| "marker_symbol": "Knstrn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1298230", | |
| "marker_symbol": "Cnot7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1298230", | |
| "marker_symbol": "Cnot7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1298378", | |
| "marker_symbol": "Dhcr7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1298392", | |
| "marker_symbol": "Bscl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1306823", | |
| "marker_symbol": "Dhx8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1309478", | |
| "marker_symbol": "Baz1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1314653", | |
| "marker_symbol": "Afdn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1314653", | |
| "marker_symbol": "Afdn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1316658", | |
| "marker_symbol": "Cyba", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1316678", | |
| "marker_symbol": "Rad1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1321396", | |
| "marker_symbol": "Pstpip1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0013763", | |
| "mp_term_name": "increased T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1328360", | |
| "marker_symbol": "Arid3a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Insulin Blood Level", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002079", | |
| "mp_term_name": "increased circulating insulin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1329038", | |
| "marker_symbol": "Mllt10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1329038", | |
| "marker_symbol": "Mllt10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1329038", | |
| "marker_symbol": "Mllt10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E9.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1329038", | |
| "marker_symbol": "Mllt10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1330293", | |
| "marker_symbol": "Krtap8-1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000162", "mp_term_name": "lordosis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1330806", | |
| "marker_symbol": "Arg2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1330806", | |
| "marker_symbol": "Arg2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000162", "mp_term_name": "lordosis" }, | |
| { "mp_term_id": "MP:0000160", "mp_term_name": "kyphosis" }, | |
| { "mp_term_id": "MP:0004174", "mp_term_name": "abnormal spine curvature" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333114", | |
| "marker_symbol": "Pigq", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333114", | |
| "marker_symbol": "Pigq", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001691", "mp_term_name": "abnormal somite shape" }, | |
| { | |
| "mp_term_id": "MP:0003229", | |
| "mp_term_name": "abnormal vitelline vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| }, | |
| { "mp_term_id": "MP:0001722", "mp_term_name": "pale yolk sac" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001726", | |
| "mp_term_name": "abnormal allantois morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001672", | |
| "mp_term_name": "abnormal embryo development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002824", | |
| "mp_term_name": "abnormal chorioallantoic fusion" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001706", | |
| "mp_term_name": "abnormal left-right axis patterning" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001718", | |
| "mp_term_name": "abnormal visceral yolk sac morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002861", | |
| "mp_term_name": "abnormal tail bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 16 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333114", | |
| "marker_symbol": "Pigq", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333753", | |
| "marker_symbol": "Pdcd6ip", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002834", "mp_term_name": "decreased heart weight" }, | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333753", | |
| "marker_symbol": "Pdcd6ip", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333786", | |
| "marker_symbol": "Car6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333853", | |
| "marker_symbol": "Hs3st3b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1336167", | |
| "marker_symbol": "Prkab1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1336993", | |
| "marker_symbol": "Ap4e1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Indirect Calorimetry", | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010090", | |
| "mp_term_name": "increased circulating creatine kinase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008806", | |
| "mp_term_name": "increased circulating amylase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005278", | |
| "mp_term_name": "abnormal cholesterol homeostasis" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005554", | |
| "mp_term_name": "decreased circulating creatinine level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002942", | |
| "mp_term_name": "decreased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010379", | |
| "mp_term_name": "decreased respiratory quotient" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003020", | |
| "mp_term_name": "decreased circulating chloride level" | |
| } | |
| ], | |
| "phenotype_count": 14 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1336993", | |
| "marker_symbol": "Ap4e1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Echo", "Heart Dissection", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003393", | |
| "mp_term_name": "decreased cardiac output" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005599", | |
| "mp_term_name": "increased cardiac muscle contractility" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003929", | |
| "mp_term_name": "decreased heart rate variability" | |
| }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" }, | |
| { | |
| "mp_term_id": "MP:0004122", | |
| "mp_term_name": "abnormal sinus arrhythmia" | |
| }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1337080", | |
| "marker_symbol": "Ncor2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-Ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004357", "mp_term_name": "long tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1337080", | |
| "marker_symbol": "Ncor2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001614", | |
| "mp_term_name": "abnormal blood vessel morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338755", | |
| "marker_symbol": "Rnd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011874", | |
| "mp_term_name": "enlarged urinary bladder" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000538", | |
| "mp_term_name": "abnormal urinary bladder morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338755", | |
| "marker_symbol": "Rnd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002997", | |
| "mp_term_name": "enlarged seminal vesicle" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001944", | |
| "mp_term_name": "abnormal pancreas morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338850", | |
| "marker_symbol": "Mthfd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338898", | |
| "marker_symbol": "Padi4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1339711", | |
| "marker_symbol": "Myh1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Urinalysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011471", | |
| "mp_term_name": "decreased urine creatinine level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003870", | |
| "mp_term_name": "decreased urine glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011436", | |
| "mp_term_name": "decreased urine magnesium level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1339795", | |
| "marker_symbol": "Smc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0001186", | |
| "top_level_mp_term_name": "pigmentation phenotype" | |
| }, | |
| "procedures": ["Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1339795", | |
| "marker_symbol": "Smc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Dexa-scan analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1339795", | |
| "marker_symbol": "Smc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1341087", | |
| "marker_symbol": "Tnks", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1341724", | |
| "marker_symbol": "Ggps1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1341724", | |
| "marker_symbol": "Ggps1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000367", | |
| "mp_term_name": "abnormal coat/ hair morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1343087", | |
| "marker_symbol": "Pdk2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1343087", | |
| "marker_symbol": "Pdk2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1344408", | |
| "marker_symbol": "Pebp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1344408", | |
| "marker_symbol": "Pebp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005084", | |
| "mp_term_name": "abnormal gallbladder morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1344408", | |
| "marker_symbol": "Pebp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345142", | |
| "marker_symbol": "Ik", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345142", | |
| "marker_symbol": "Ik", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345282", | |
| "marker_symbol": "Slc30a4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345283", | |
| "marker_symbol": "Slc25a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002102", "mp_term_name": "abnormal ear morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345643", | |
| "marker_symbol": "Sufu", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004848", "mp_term_name": "abnormal liver size" }, | |
| { "mp_term_id": "MP:0000603", "mp_term_name": "pale liver" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345643", | |
| "marker_symbol": "Sufu", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345643", | |
| "marker_symbol": "Sufu", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003717", "mp_term_name": "pallor" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1349216", | |
| "marker_symbol": "Abcd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1349400", | |
| "marker_symbol": "Cops7a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1349400", | |
| "marker_symbol": "Cops7a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1349447", | |
| "marker_symbol": "Cln8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1349475", | |
| "marker_symbol": "Ppp2r5c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1349475", | |
| "marker_symbol": "Ppp2r5c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Light-Dark Test", | |
| "Grip Strength", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1350341", | |
| "marker_symbol": "Sgsh", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1350360", | |
| "marker_symbol": "Tspan32", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351334", | |
| "marker_symbol": "Syn3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351629", | |
| "marker_symbol": "Pign", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351629", | |
| "marker_symbol": "Pign", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351629", | |
| "marker_symbol": "Pign", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352447", | |
| "marker_symbol": "Abcc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003917", "mp_term_name": "increased kidney weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352459", | |
| "marker_symbol": "Nr6a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352459", | |
| "marker_symbol": "Nr6a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002861", | |
| "mp_term_name": "abnormal tail bud morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001672", | |
| "mp_term_name": "abnormal embryo development" | |
| }, | |
| { "mp_term_id": "MP:0001691", "mp_term_name": "abnormal somite shape" }, | |
| { | |
| "mp_term_id": "MP:0002824", | |
| "mp_term_name": "abnormal chorioallantoic fusion" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001718", | |
| "mp_term_name": "abnormal visceral yolk sac morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| }, | |
| { "mp_term_id": "MP:0001722", "mp_term_name": "pale yolk sac" }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001726", | |
| "mp_term_name": "abnormal allantois morphology" | |
| } | |
| ], | |
| "phenotype_count": 13 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352760", | |
| "marker_symbol": "Hdgfl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353466", | |
| "marker_symbol": "Mmp20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0013129", "mp_term_name": "abnormal tooth color" }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353569", | |
| "marker_symbol": "Foxe3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353592", | |
| "marker_symbol": "Hacd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353644", | |
| "marker_symbol": "Zfp503", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000433", "mp_term_name": "microcephaly" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353644", | |
| "marker_symbol": "Zfp503", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353644", | |
| "marker_symbol": "Zfp503", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354170", | |
| "marker_symbol": "Cbarp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354702", | |
| "marker_symbol": "Fbxl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| }, | |
| { "mp_term_id": "MP:0001891", "mp_term_name": "hydrocephaly" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354702", | |
| "marker_symbol": "Fbxl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354951", | |
| "marker_symbol": "Gne", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354956", | |
| "marker_symbol": "Tfr2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008810", | |
| "mp_term_name": "increased circulating iron level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1355330", | |
| "marker_symbol": "Phgdh", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011495", "mp_term_name": "abnormal head shape" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858213", | |
| "marker_symbol": "Clpp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858213", | |
| "marker_symbol": "Clpp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858277", | |
| "marker_symbol": "Gal3st1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002797", "mp_term_name": "increased thigmotaxis" }, | |
| { | |
| "mp_term_id": "MP:0001363", | |
| "mp_term_name": "increased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0000745", "mp_term_name": "tremors" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0001406", "mp_term_name": "abnormal gait" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858910", | |
| "marker_symbol": "Jmjd6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Rotarod", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001488", | |
| "mp_term_name": "increased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001516", | |
| "mp_term_name": "abnormal motor coordination/balance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858910", | |
| "marker_symbol": "Jmjd6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["FACs Analysis"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008044", "mp_term_name": "increased NK cell number" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859162", | |
| "marker_symbol": "Rnf10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Electrocardiogram (ECG)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003928", | |
| "mp_term_name": "increased heart rate variability" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { "mp_term_id": "MP:0010571", "mp_term_name": "shortened ST segment" }, | |
| { "mp_term_id": "MP:0003900", "mp_term_name": "shortened QT interval" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859162", | |
| "marker_symbol": "Rnf10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Haematology test", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012362", | |
| "mp_term_name": "increased large unstained cell number" | |
| }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0004953", "mp_term_name": "decreased spleen weight" }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 12 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859170", | |
| "marker_symbol": "Pdcd7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859631", | |
| "marker_symbol": "Pdgfc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859631", | |
| "marker_symbol": "Pdgfc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008079", | |
| "mp_term_name": "decreased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013678", | |
| "mp_term_name": "decreased Ly6C-positive NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013691", | |
| "mp_term_name": "decreased CD5-positive Ly6C-positive T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008168", | |
| "mp_term_name": "decreased B-1a cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010850", | |
| "mp_term_name": "increased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013676", | |
| "mp_term_name": "increased Ly6C-positive mature NK cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0008207", | |
| "mp_term_name": "decreased B-2 B cell number" | |
| }, | |
| { "mp_term_id": "MP:0005017", "mp_term_name": "decreased B cell number" }, | |
| { | |
| "mp_term_id": "MP:0008174", | |
| "mp_term_name": "decreased follicular B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013772", | |
| "mp_term_name": "increased effector memory T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013435", | |
| "mp_term_name": "decreased CD8-positive, naive alpha-beta T cell number" | |
| } | |
| ], | |
| "phenotype_count": 12 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859631", | |
| "marker_symbol": "Pdgfc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859631", | |
| "marker_symbol": "Pdgfc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859661", | |
| "marker_symbol": "Atp11c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859661", | |
| "marker_symbol": "Atp11c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859665", | |
| "marker_symbol": "Atp8b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859866", | |
| "marker_symbol": "Cdc20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860078", | |
| "marker_symbol": "Txnl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860188", | |
| "marker_symbol": "Snx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011495", "mp_term_name": "abnormal head shape" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860188", | |
| "marker_symbol": "Snx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860188", | |
| "marker_symbol": "Snx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011495", "mp_term_name": "abnormal head shape" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860765", | |
| "marker_symbol": "Extl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860765", | |
| "marker_symbol": "Extl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1888496", | |
| "marker_symbol": "Tbx20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E9.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003229", | |
| "mp_term_name": "abnormal vitelline vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001718", | |
| "mp_term_name": "abnormal visceral yolk sac morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1888520", | |
| "marker_symbol": "Brd4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011959", | |
| "mp_term_name": "abnormal eye posterior chamber depth" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003731", | |
| "mp_term_name": "abnormal retina outer nuclear layer morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011965", | |
| "mp_term_name": "decreased total retina thickness" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003733", | |
| "mp_term_name": "abnormal retina inner nuclear layer morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1888921", | |
| "marker_symbol": "P3h1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Electrocardiogram (ECG)" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1888921", | |
| "marker_symbol": "P3h1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1889001", | |
| "marker_symbol": "Nub1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0008725", "mp_term_name": "enlarged heart atrium" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1889341", | |
| "marker_symbol": "Hacd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890165", | |
| "marker_symbol": "Larp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890165", | |
| "marker_symbol": "Larp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { "mp_term_id": "MP:0003642", "mp_term_name": "absent seminal vesicle" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890219", | |
| "marker_symbol": "Cdh23", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001512", "mp_term_name": "trunk curl" }, | |
| { | |
| "mp_term_id": "MP:0001523", | |
| "mp_term_name": "impaired righting response" | |
| }, | |
| { "mp_term_id": "MP:0001406", "mp_term_name": "abnormal gait" }, | |
| { "mp_term_id": "MP:0001408", "mp_term_name": "stereotypic behavior" }, | |
| { "mp_term_id": "MP:0006358", "mp_term_name": "absent pinna reflex" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890219", | |
| "marker_symbol": "Cdh23", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890494", | |
| "marker_symbol": "Laptm4b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890494", | |
| "marker_symbol": "Laptm4b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890520", | |
| "marker_symbol": "Vps4a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890659", | |
| "marker_symbol": "Trim39", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013278", | |
| "mp_term_name": "decreased fasting circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890659", | |
| "marker_symbol": "Trim39", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { "mp_term_id": "MP:0001307", "mp_term_name": "fused cornea and lens" }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| }, | |
| { "mp_term_id": "MP:0005542", "mp_term_name": "corneal vascularization" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891112", | |
| "marker_symbol": "Gmds", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891112", | |
| "marker_symbol": "Gmds", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891160", | |
| "marker_symbol": "Chst2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891160", | |
| "marker_symbol": "Chst2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891160", | |
| "marker_symbol": "Chst2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891295", | |
| "marker_symbol": "Ube3b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000183", | |
| "mp_term_name": "decreased circulating LDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891295", | |
| "marker_symbol": "Ube3b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891346", | |
| "marker_symbol": "Fgf20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { "mp_term_id": "MP:0003918", "mp_term_name": "decreased kidney weight" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891690", | |
| "marker_symbol": "Syncrip", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891704", | |
| "marker_symbol": "Hbs1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891704", | |
| "marker_symbol": "Hbs1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Ear epidermis immunophenotyping", | |
| "Bone marrow immunophenotyping", | |
| "Hematology", | |
| "Spleen Immunophenotyping", | |
| "Whole blood peripheral blood leukocyte immunophenotyping", | |
| "Mesenteric Lymph Node Immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010851", | |
| "mp_term_name": "decreased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013764", | |
| "mp_term_name": "decreased T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010835", | |
| "mp_term_name": "increased CD4-positive, alpha-beta memory T cell number" | |
| }, | |
| { "mp_term_id": "MP:0005505", "mp_term_name": "thrombocytosis" }, | |
| { | |
| "mp_term_id": "MP:0008119", | |
| "mp_term_name": "decreased Langerhans cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000223", | |
| "mp_term_name": "decreased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013430", | |
| "mp_term_name": "increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013421", | |
| "mp_term_name": "increased CD5-positive gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004973", | |
| "mp_term_name": "increased regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010168", | |
| "mp_term_name": "increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013513", | |
| "mp_term_name": "decreased memory-marker CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010850", | |
| "mp_term_name": "increased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008211", | |
| "mp_term_name": "decreased mature B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 16 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891827", | |
| "marker_symbol": "Gde1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891916", | |
| "marker_symbol": "Plag1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891917", | |
| "marker_symbol": "Ywhab", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004151", | |
| "mp_term_name": "decreased circulating iron level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005344", | |
| "mp_term_name": "increased circulating bilirubin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005566", | |
| "mp_term_name": "decreased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913310", | |
| "marker_symbol": "Cystm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913390", | |
| "marker_symbol": "Ska2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913647", | |
| "marker_symbol": "Sar1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913693", | |
| "marker_symbol": "Tnfaip8l1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913693", | |
| "marker_symbol": "Tnfaip8l1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913693", | |
| "marker_symbol": "Tnfaip8l1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913758", | |
| "marker_symbol": "Lamtor1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913771", | |
| "marker_symbol": "Rwdd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Spleen Immunophenotyping", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008079", | |
| "mp_term_name": "decreased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013675", | |
| "mp_term_name": "decreased Ly6C-positive mature NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004974", | |
| "mp_term_name": "decreased regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013418", | |
| "mp_term_name": "increased memory-marker gamma-delta T cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913775", | |
| "marker_symbol": "Timm50", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913789", | |
| "marker_symbol": "Xpo5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913865", | |
| "marker_symbol": "Atg4b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913865", | |
| "marker_symbol": "Atg4b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913879", | |
| "marker_symbol": "Golph3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913879", | |
| "marker_symbol": "Golph3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913906", | |
| "marker_symbol": "Eef1d", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913941", | |
| "marker_symbol": "Gapvd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913955", | |
| "marker_symbol": "Dnase1l2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Echo" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0006203", "mp_term_name": "eye hemorrhage" }, | |
| { | |
| "mp_term_id": "MP:0011952", | |
| "mp_term_name": "decreased cardiac stroke volume" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0003921", | |
| "mp_term_name": "abnormal heart left ventricle morphology" | |
| }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913955", | |
| "marker_symbol": "Dnase1l2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913955", | |
| "marker_symbol": "Dnase1l2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914008", | |
| "marker_symbol": "Zfp474", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914008", | |
| "marker_symbol": "Zfp474", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914060", | |
| "marker_symbol": "Rbm22", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001489", "mp_term_name": "decreased startle reflex" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914060", | |
| "marker_symbol": "Rbm22", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004931", "mp_term_name": "enlarged epididymis" }, | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002631", | |
| "mp_term_name": "abnormal epididymis morphology" | |
| }, | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914060", | |
| "marker_symbol": "Rbm22", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003050", | |
| "mp_term_name": "abnormal sacral vertebrae morphology" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0003049", | |
| "mp_term_name": "abnormal lumbar vertebrae morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914060", | |
| "marker_symbol": "Rbm22", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914061", | |
| "marker_symbol": "Duoxa2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Bone marrow immunophenotyping", | |
| "Hematology", | |
| "Spleen Immunophenotyping", | |
| "Mesenteric Lymph Node Immunophenotyping", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008078", | |
| "mp_term_name": "increased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013436", | |
| "mp_term_name": "increased CD8-positive, naive alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013771", | |
| "mp_term_name": "decreased effector memory T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008207", | |
| "mp_term_name": "decreased B-2 B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013763", | |
| "mp_term_name": "increased T-helper cell number" | |
| }, | |
| { "mp_term_id": "MP:0005017", "mp_term_name": "decreased B cell number" }, | |
| { | |
| "mp_term_id": "MP:0013417", | |
| "mp_term_name": "decreased memory-marker gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013429", | |
| "mp_term_name": "decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012764", | |
| "mp_term_name": "increased alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008079", | |
| "mp_term_name": "decreased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013026", | |
| "mp_term_name": "decreased Ly6C low monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008524", | |
| "mp_term_name": "increased plasmacytoid dendritic cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010168", | |
| "mp_term_name": "increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008215", | |
| "mp_term_name": "decreased immature B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010850", | |
| "mp_term_name": "increased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012768", | |
| "mp_term_name": "decreased KLRG1-positive NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013649", | |
| "mp_term_name": "decreased CD11b-high dendritic cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009923", | |
| "mp_term_name": "decreased transitional stage T1 B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008211", | |
| "mp_term_name": "decreased mature B cell number" | |
| }, | |
| { "mp_term_id": "MP:0005015", "mp_term_name": "increased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0008174", | |
| "mp_term_name": "decreased follicular B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| }, | |
| { "mp_term_id": "MP:0008045", "mp_term_name": "decreased NK cell number" } | |
| ], | |
| "phenotype_count": 25 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914061", | |
| "marker_symbol": "Duoxa2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000552", | |
| "mp_term_name": "abnormal radius morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005296", | |
| "mp_term_name": "abnormal humerus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010099", | |
| "mp_term_name": "abnormal thoracic cage shape" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002932", | |
| "mp_term_name": "abnormal joint morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000137", | |
| "mp_term_name": "abnormal vertebrae morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000558", | |
| "mp_term_name": "abnormal tibia morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000559", | |
| "mp_term_name": "abnormal femur morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004599", | |
| "mp_term_name": "abnormal vertebral arch morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005270", | |
| "mp_term_name": "abnormal zygomatic bone morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005298", | |
| "mp_term_name": "abnormal clavicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| }, | |
| { "mp_term_id": "MP:0005108", "mp_term_name": "abnormal ulna morphology" } | |
| ], | |
| "phenotype_count": 15 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914061", | |
| "marker_symbol": "Duoxa2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002073", "mp_term_name": "abnormal hair growth" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914072", | |
| "marker_symbol": "Fbxo25", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004599", | |
| "mp_term_name": "abnormal vertebral arch morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914080", | |
| "marker_symbol": "Nacc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008528", "mp_term_name": "polycystic kidney" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914080", | |
| "marker_symbol": "Nacc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914080", | |
| "marker_symbol": "Nacc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914080", | |
| "marker_symbol": "Nacc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011965", | |
| "mp_term_name": "decreased total retina thickness" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914118", | |
| "marker_symbol": "Mfsd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914118", | |
| "marker_symbol": "Mfsd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914167", | |
| "marker_symbol": "Chordc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914167", | |
| "marker_symbol": "Chordc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914220", | |
| "marker_symbol": "Ssbp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914228", | |
| "marker_symbol": "Luc7l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914244", | |
| "marker_symbol": "Cep19", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914256", | |
| "marker_symbol": "Cisd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open-field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914256", | |
| "marker_symbol": "Cisd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914256", | |
| "marker_symbol": "Cisd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Dysmorphology", "Slit Lamp"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005542", "mp_term_name": "corneal vascularization" }, | |
| { "mp_term_id": "MP:0002697", "mp_term_name": "abnormal eye size" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914342", | |
| "marker_symbol": "Gatm", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004156", "mp_term_name": "abnormal QT variability" }, | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0003233", "mp_term_name": "prolonged QT interval" }, | |
| { | |
| "mp_term_id": "MP:0010392", | |
| "mp_term_name": "prolonged QRS complex duration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003928", | |
| "mp_term_name": "increased heart rate variability" | |
| }, | |
| { "mp_term_id": "MP:0010570", "mp_term_name": "prolonged ST segment" }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" }, | |
| { | |
| "mp_term_id": "MP:0004122", | |
| "mp_term_name": "abnormal sinus arrhythmia" | |
| } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914342", | |
| "marker_symbol": "Gatm", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" }, | |
| { | |
| "mp_term_id": "MP:0010068", | |
| "mp_term_name": "decreased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914346", | |
| "marker_symbol": "Mmachc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914383", | |
| "marker_symbol": "Gp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914457", | |
| "marker_symbol": "Lsm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914457", | |
| "marker_symbol": "Lsm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Echo", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010574", "mp_term_name": "dilated aorta" }, | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { | |
| "mp_term_id": "MP:0003928", | |
| "mp_term_name": "increased heart rate variability" | |
| }, | |
| { "mp_term_id": "MP:0002953", "mp_term_name": "thick ventricular wall" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914649", | |
| "marker_symbol": "Pdlim7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914688", | |
| "marker_symbol": "Rfk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { "mp_term_id": "MP:0003604", "mp_term_name": "single kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914690", | |
| "marker_symbol": "Mtpap", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001392", | |
| "mp_term_name": "abnormal locomotor behavior" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914720", | |
| "marker_symbol": "Abcg8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005553", | |
| "mp_term_name": "increased circulating creatinine level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004151", | |
| "mp_term_name": "decreased circulating iron level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005634", | |
| "mp_term_name": "decreased circulating sodium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005278", | |
| "mp_term_name": "abnormal cholesterol homeostasis" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 11 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914720", | |
| "marker_symbol": "Abcg8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Echo"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005599", | |
| "mp_term_name": "increased cardiac muscle contractility" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003921", | |
| "mp_term_name": "abnormal heart left ventricle morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914779", | |
| "marker_symbol": "Fgfr1op2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914961", | |
| "marker_symbol": "Nsmce1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915023", | |
| "marker_symbol": "Kat8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915023", | |
| "marker_symbol": "Kat8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915040", | |
| "marker_symbol": "Rab39b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915040", | |
| "marker_symbol": "Rab39b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915040", | |
| "marker_symbol": "Rab39b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001127", "mp_term_name": "small ovary" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915171", | |
| "marker_symbol": "Ube2f", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915171", | |
| "marker_symbol": "Ube2f", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915255", | |
| "marker_symbol": "Naa10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915255", | |
| "marker_symbol": "Naa10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915349", | |
| "marker_symbol": "Cibar1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915362", | |
| "marker_symbol": "Entr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915415", | |
| "marker_symbol": "Fdx2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003917", "mp_term_name": "increased kidney weight" }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915415", | |
| "marker_symbol": "Fdx2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0012360", | |
| "mp_term_name": "abnormal large unstained cell number" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915437", | |
| "marker_symbol": "Fam135a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Fear Conditioning", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0020421", | |
| "mp_term_name": "increased freezing behavior" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001363", | |
| "mp_term_name": "increased anxiety-related response" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915501", | |
| "marker_symbol": "Babam1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping", | |
| "Hematology" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013519", | |
| "mp_term_name": "decreased CD4-positive NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008040", | |
| "mp_term_name": "decreased NK T cell number" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915513", | |
| "marker_symbol": "Pdhb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915513", | |
| "marker_symbol": "Pdhb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915599", | |
| "marker_symbol": "Ndufs3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Dexa-scan analysis", "Heart Dissection", "IPGTT"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001260", "mp_term_name": "increased body weight" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915775", | |
| "marker_symbol": "Evc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005084", | |
| "mp_term_name": "abnormal gallbladder morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915775", | |
| "marker_symbol": "Evc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916043", | |
| "marker_symbol": "Rab3gap2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005344", | |
| "mp_term_name": "increased circulating bilirubin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916043", | |
| "marker_symbol": "Rab3gap2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916043", | |
| "marker_symbol": "Rab3gap2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916096", | |
| "marker_symbol": "Rnf208", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Lung mechanics by forced oscillations" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0009342", "mp_term_name": "enlarged gallbladder" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916125", | |
| "marker_symbol": "Tmcc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000494", | |
| "mp_term_name": "abnormal cecum morphology" | |
| }, | |
| { "mp_term_id": "MP:0009476", "mp_term_name": "enlarged cecum" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916161", | |
| "marker_symbol": "Pygo2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916289", | |
| "marker_symbol": "Insig1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000455", | |
| "mp_term_name": "abnormal maxilla morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916295", | |
| "marker_symbol": "Trappc2l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916351", | |
| "marker_symbol": "Ydjc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916380", | |
| "marker_symbol": "Vps13b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916709", | |
| "marker_symbol": "Ubl7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916720", | |
| "marker_symbol": "Tmem127", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916818", | |
| "marker_symbol": "Vkorc1l1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field - centre start", "Light-Dark Test"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916942", | |
| "marker_symbol": "Hddc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916942", | |
| "marker_symbol": "Hddc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916947", | |
| "marker_symbol": "Camsap3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008346", | |
| "mp_term_name": "increased gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916966", | |
| "marker_symbol": "Trip13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916966", | |
| "marker_symbol": "Trip13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916966", | |
| "marker_symbol": "Trip13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916966", | |
| "marker_symbol": "Trip13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916978", | |
| "marker_symbol": "Card11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Fear Conditioning"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0020421", | |
| "mp_term_name": "increased freezing behavior" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916978", | |
| "marker_symbol": "Card11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010851", | |
| "mp_term_name": "decreased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008078", | |
| "mp_term_name": "increased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0013436", | |
| "mp_term_name": "increased CD8-positive, naive alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013771", | |
| "mp_term_name": "decreased effector memory T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013763", | |
| "mp_term_name": "increased T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010169", | |
| "mp_term_name": "decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" }, | |
| { "mp_term_id": "MP:0005015", "mp_term_name": "increased T cell number" }, | |
| { "mp_term_id": "MP:0004953", "mp_term_name": "decreased spleen weight" }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| } | |
| ], | |
| "phenotype_count": 15 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916978", | |
| "marker_symbol": "Card11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010851", | |
| "mp_term_name": "decreased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008078", | |
| "mp_term_name": "increased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0013436", | |
| "mp_term_name": "increased CD8-positive, naive alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013771", | |
| "mp_term_name": "decreased effector memory T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013763", | |
| "mp_term_name": "increased T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010169", | |
| "mp_term_name": "decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" }, | |
| { "mp_term_id": "MP:0005015", "mp_term_name": "increased T cell number" }, | |
| { "mp_term_id": "MP:0004953", "mp_term_name": "decreased spleen weight" }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| } | |
| ], | |
| "phenotype_count": 15 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917004", | |
| "marker_symbol": "Fbxo7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917087", | |
| "marker_symbol": "Pcgf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917226", | |
| "marker_symbol": "Galk2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917258", | |
| "marker_symbol": "Ace2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917264", | |
| "marker_symbol": "Kat14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010090", | |
| "mp_term_name": "increased circulating creatine kinase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010092", | |
| "mp_term_name": "increased circulating magnesium level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917352", | |
| "marker_symbol": "Dnmbp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917428", | |
| "marker_symbol": "Abhd17c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009552", | |
| "mp_term_name": "urinary bladder obstruction" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917428", | |
| "marker_symbol": "Abhd17c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917488", | |
| "marker_symbol": "Rnf168", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Gross Pathology and Tissue Collection", | |
| "Electrocardiogram (ECG)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010392", | |
| "mp_term_name": "prolonged QRS complex duration" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917488", | |
| "marker_symbol": "Rnf168", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005287", "mp_term_name": "narrow eye opening" }, | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0001307", "mp_term_name": "fused cornea and lens" }, | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0005176", "mp_term_name": "eyelids fail to open" }, | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001303", | |
| "mp_term_name": "abnormal lens morphology" | |
| }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 13 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917488", | |
| "marker_symbol": "Rnf168", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| }, | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917550", | |
| "marker_symbol": "Fuz", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917562", | |
| "marker_symbol": "Cactin", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917675", | |
| "marker_symbol": "Csnk1g3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010088", | |
| "mp_term_name": "decreased circulating fructosamine level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000182", | |
| "mp_term_name": "increased circulating LDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002966", | |
| "mp_term_name": "decreased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917675", | |
| "marker_symbol": "Csnk1g3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917802", | |
| "marker_symbol": "Lrrc56", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917802", | |
| "marker_symbol": "Lrrc56", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001175", "mp_term_name": "abnormal lung morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917802", | |
| "marker_symbol": "Lrrc56", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917802", | |
| "marker_symbol": "Lrrc56", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917802", | |
| "marker_symbol": "Lrrc56", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917858", | |
| "marker_symbol": "Btbd7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917936", | |
| "marker_symbol": "Dusp16", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1918127", | |
| "marker_symbol": "Micalcl", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011874", | |
| "mp_term_name": "enlarged urinary bladder" | |
| }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1918287", | |
| "marker_symbol": "Prss55", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1918529", | |
| "marker_symbol": "Slc29a3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1918529", | |
| "marker_symbol": "Slc29a3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1918529", | |
| "marker_symbol": "Slc29a3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" }, | |
| { "mp_term_id": "MP:0002637", "mp_term_name": "small uterus" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1918550", | |
| "marker_symbol": "Rnf148", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0002286", "mp_term_name": "cryptorchism" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1918876", | |
| "marker_symbol": "Gimap6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Spleen Immunophenotyping", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013510", | |
| "mp_term_name": "decreased CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013513", | |
| "mp_term_name": "decreased memory-marker CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013514", | |
| "mp_term_name": "increased memory-marker CD4-negative NK T cell number" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1918944", | |
| "marker_symbol": "Ipo9", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002861", | |
| "mp_term_name": "abnormal tail bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919003", | |
| "marker_symbol": "Tmprss6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919128", | |
| "marker_symbol": "Fam83d", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919129", | |
| "marker_symbol": "Acsl5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919131", | |
| "marker_symbol": "Apmap", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919131", | |
| "marker_symbol": "Apmap", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Body Composition (DEXA lean/fat)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000452", | |
| "mp_term_name": "abnormal mouth morphology" | |
| }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919131", | |
| "marker_symbol": "Apmap", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000452", | |
| "mp_term_name": "abnormal mouth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919225", | |
| "marker_symbol": "Fam53a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919225", | |
| "marker_symbol": "Fam53a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919225", | |
| "marker_symbol": "Fam53a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919254", | |
| "marker_symbol": "C1qtnf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919254", | |
| "marker_symbol": "C1qtnf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000494", | |
| "mp_term_name": "abnormal cecum morphology" | |
| }, | |
| { "mp_term_id": "MP:0009476", "mp_term_name": "enlarged cecum" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919264", | |
| "marker_symbol": "Btbd17", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008528", "mp_term_name": "polycystic kidney" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919305", | |
| "marker_symbol": "Slc38a10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Indirect ophthalmoscopy"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919551", | |
| "marker_symbol": "Shisal1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919599", | |
| "marker_symbol": "Dusp3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005296", | |
| "mp_term_name": "abnormal humerus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919600", | |
| "marker_symbol": "Zc2hc1c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919649", | |
| "marker_symbol": "Brap", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Fear Conditioning"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0020421", | |
| "mp_term_name": "increased freezing behavior" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919792", | |
| "marker_symbol": "Pgam5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919792", | |
| "marker_symbol": "Pgam5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919819", | |
| "marker_symbol": "Bbs5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919899", | |
| "marker_symbol": "Tmem209", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919899", | |
| "marker_symbol": "Tmem209", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919899", | |
| "marker_symbol": "Tmem209", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919918", | |
| "marker_symbol": "Skida1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919918", | |
| "marker_symbol": "Skida1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1919924", | |
| "marker_symbol": "Adipor1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920014", | |
| "marker_symbol": "Csnk1g2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005559", | |
| "mp_term_name": "increased circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001566", | |
| "mp_term_name": "increased circulating phosphate level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920093", | |
| "marker_symbol": "Prdm4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011874", "mp_term_name": "enlarged urinary bladder" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920145", | |
| "marker_symbol": "Setd5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { "mp_term_id": "MP:0006358", "mp_term_name": "absent pinna reflex" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920198", | |
| "marker_symbol": "Tppp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005564", | |
| "mp_term_name": "increased hemoglobin content" | |
| }, | |
| { "mp_term_id": "MP:0002608", "mp_term_name": "increased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0003131", | |
| "mp_term_name": "increased erythrocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920230", | |
| "marker_symbol": "Wdr11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920393", | |
| "marker_symbol": "Wdr37", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004613", | |
| "mp_term_name": "fusion of vertebral arches" | |
| }, | |
| { "mp_term_id": "MP:0000160", "mp_term_name": "kyphosis" }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004174", | |
| "mp_term_name": "abnormal spine curvature" | |
| }, | |
| { "mp_term_id": "MP:0004609", "mp_term_name": "vertebral fusion" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920421", | |
| "marker_symbol": "Trmt10a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920455", | |
| "marker_symbol": "C9orf72", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004599", | |
| "mp_term_name": "abnormal vertebral arch morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920907", | |
| "marker_symbol": "Fbrsl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000157", | |
| "mp_term_name": "abnormal sternum morphology" | |
| }, | |
| { "mp_term_id": "MP:0004609", "mp_term_name": "vertebral fusion" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920939", | |
| "marker_symbol": "Bloc1s2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000603", "mp_term_name": "pale liver" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920939", | |
| "marker_symbol": "Bloc1s2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Plasma Chemistry", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002702", | |
| "mp_term_name": "decreased circulating free fatty acids level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920939", | |
| "marker_symbol": "Bloc1s2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920970", | |
| "marker_symbol": "Cst6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1920997", | |
| "marker_symbol": "Shld1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921152", | |
| "marker_symbol": "Psmb11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921269", | |
| "marker_symbol": "Traf3ip1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001691", "mp_term_name": "abnormal somite shape" }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921371", | |
| "marker_symbol": "Acoxl", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921371", | |
| "marker_symbol": "Acoxl", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921409", | |
| "marker_symbol": "Acbd5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921527", | |
| "marker_symbol": "Chic2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921527", | |
| "marker_symbol": "Chic2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921569", | |
| "marker_symbol": "Mettl23", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921569", | |
| "marker_symbol": "Mettl23", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011964", | |
| "mp_term_name": "increased total retina thickness" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921569", | |
| "marker_symbol": "Mettl23", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921599", | |
| "marker_symbol": "Fam160a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921599", | |
| "marker_symbol": "Fam160a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921599", | |
| "marker_symbol": "Fam160a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001363", | |
| "mp_term_name": "increased anxiety-related response" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921627", | |
| "marker_symbol": "Hsf2bp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921638", | |
| "marker_symbol": "Dpp8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921638", | |
| "marker_symbol": "Dpp8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0002834", "mp_term_name": "decreased heart weight" }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921783", | |
| "marker_symbol": "Gzf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1921783", | |
| "marker_symbol": "Gzf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922033", | |
| "marker_symbol": "Fbf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922035", | |
| "marker_symbol": "Miga2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Dexa-scan analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922035", | |
| "marker_symbol": "Miga2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922035", | |
| "marker_symbol": "Miga2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Haematology test"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922656", | |
| "marker_symbol": "Ndufs7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922672", | |
| "marker_symbol": "Mettl5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004222", "mp_term_name": "iris synechia" }, | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001303", | |
| "mp_term_name": "abnormal lens morphology" | |
| }, | |
| { "mp_term_id": "MP:0001322", "mp_term_name": "abnormal iris morphology" } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922680", | |
| "marker_symbol": "Anapc15", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Placenta E12.5", | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004258", "mp_term_name": "abnormal placenta size" }, | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922776", | |
| "marker_symbol": "Eppin", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922776", | |
| "marker_symbol": "Eppin", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922776", | |
| "marker_symbol": "Eppin", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1922853", | |
| "marker_symbol": "Ppp1r35", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923257", | |
| "marker_symbol": "Zmym2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923257", | |
| "marker_symbol": "Zmym2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923275", | |
| "marker_symbol": "Cant1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001488", "mp_term_name": "increased startle reflex" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923429", | |
| "marker_symbol": "Usp31", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009141", | |
| "mp_term_name": "increased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923429", | |
| "marker_symbol": "Usp31", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923429", | |
| "marker_symbol": "Usp31", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0006243", | |
| "mp_term_name": "impaired pupillary reflex" | |
| }, | |
| { "mp_term_id": "MP:0002546", "mp_term_name": "mydriasis" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923520", | |
| "marker_symbol": "Cyrib", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923520", | |
| "marker_symbol": "Cyrib", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923552", | |
| "marker_symbol": "Pcnp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923552", | |
| "marker_symbol": "Pcnp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923605", | |
| "marker_symbol": "Tgds", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923661", | |
| "marker_symbol": "Ift43", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923718", | |
| "marker_symbol": "Uhrf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923718", | |
| "marker_symbol": "Uhrf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923718", | |
| "marker_symbol": "Uhrf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923760", | |
| "marker_symbol": "Trappc9", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923760", | |
| "marker_symbol": "Trappc9", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Spleen Immunophenotyping", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013648", | |
| "mp_term_name": "increased CD11b-high dendritic cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008347", | |
| "mp_term_name": "decreased gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013025", | |
| "mp_term_name": "increased Ly6C low monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012768", | |
| "mp_term_name": "decreased KLRG1-positive NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013652", | |
| "mp_term_name": "decreased CD11b-low dendritic cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013022", | |
| "mp_term_name": "increased Ly6C high monocyte number" | |
| } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923799", | |
| "marker_symbol": "Cecr2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923799", | |
| "marker_symbol": "Cecr2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923800", | |
| "marker_symbol": "Cenpo", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Plasma Chemistry", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002702", | |
| "mp_term_name": "decreased circulating free fatty acids level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004151", | |
| "mp_term_name": "decreased circulating iron level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005566", | |
| "mp_term_name": "decreased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923800", | |
| "marker_symbol": "Cenpo", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923805", | |
| "marker_symbol": "Mmaa", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923805", | |
| "marker_symbol": "Mmaa", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923805", | |
| "marker_symbol": "Mmaa", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923827", | |
| "marker_symbol": "Faf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923827", | |
| "marker_symbol": "Faf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923858", | |
| "marker_symbol": "Hectd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923858", | |
| "marker_symbol": "Hectd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000706", "mp_term_name": "small thymus" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1923957", | |
| "marker_symbol": "Clasp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924139", | |
| "marker_symbol": "Coq8b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924139", | |
| "marker_symbol": "Coq8b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924139", | |
| "marker_symbol": "Coq8b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924234", | |
| "marker_symbol": "Katnal2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924298", | |
| "marker_symbol": "Cep83", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924337", | |
| "marker_symbol": "Ankrd11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001672", | |
| "mp_term_name": "abnormal embryo development" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924627", | |
| "marker_symbol": "Kcnt1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924712", | |
| "marker_symbol": "Tmem116", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005292", | |
| "mp_term_name": "improved glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002966", | |
| "mp_term_name": "decreased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924712", | |
| "marker_symbol": "Tmem116", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924809", | |
| "marker_symbol": "Agl", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924809", | |
| "marker_symbol": "Agl", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924823", | |
| "marker_symbol": "Vps33a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0000157", | |
| "mp_term_name": "abnormal sternum morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924833", | |
| "marker_symbol": "Notum", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001127", "mp_term_name": "small ovary" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1924880", | |
| "marker_symbol": "Prdm8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925164", | |
| "marker_symbol": "Krtap17-1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003917", "mp_term_name": "increased kidney weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925164", | |
| "marker_symbol": "Krtap17-1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925164", | |
| "marker_symbol": "Krtap17-1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925230", | |
| "marker_symbol": "Sbf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925230", | |
| "marker_symbol": "Sbf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925554", | |
| "marker_symbol": "Naa38", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925559", | |
| "marker_symbol": "Cul9", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011971", | |
| "mp_term_name": "increased circulating lactate dehydrogenase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010090", | |
| "mp_term_name": "increased circulating creatine kinase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005565", | |
| "mp_term_name": "increased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925664", | |
| "marker_symbol": "1700034E13Rik", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925938", | |
| "marker_symbol": "Nol3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1925938", | |
| "marker_symbol": "Nol3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926005", | |
| "marker_symbol": "Fam122b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926005", | |
| "marker_symbol": "Fam122b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926037", | |
| "marker_symbol": "Usp54", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926051", | |
| "marker_symbol": "Ak7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926051", | |
| "marker_symbol": "Ak7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000160", "mp_term_name": "kyphosis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926129", | |
| "marker_symbol": "Arid1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926163", | |
| "marker_symbol": "Ltn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Immunophenotyping", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010168", | |
| "mp_term_name": "increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926173", | |
| "marker_symbol": "Chsy3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926173", | |
| "marker_symbol": "Chsy3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926194", | |
| "marker_symbol": "Tnip1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926950", | |
| "marker_symbol": "Zfp236", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1926950", | |
| "marker_symbol": "Zfp236", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1927155", | |
| "marker_symbol": "Clptm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1927753", | |
| "marker_symbol": "Inpp5e", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000562", "mp_term_name": "polydactyly" }, | |
| { "mp_term_id": "MP:0002109", "mp_term_name": "abnormal limb morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1928323", | |
| "marker_symbol": "Nisch", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000455", | |
| "mp_term_name": "abnormal maxilla morphology" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| }, | |
| { "mp_term_id": "MP:0004174", "mp_term_name": "abnormal spine curvature" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1928753", | |
| "marker_symbol": "Pfdn5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002111", "mp_term_name": "abnormal tail morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1928753", | |
| "marker_symbol": "Pfdn5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1928849", | |
| "marker_symbol": "Svep1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005564", | |
| "mp_term_name": "increased hemoglobin content" | |
| }, | |
| { "mp_term_id": "MP:0002608", "mp_term_name": "increased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0003131", | |
| "mp_term_name": "increased erythrocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929237", | |
| "marker_symbol": "Pus1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005287", "mp_term_name": "narrow eye opening" }, | |
| { "mp_term_id": "MP:0006203", "mp_term_name": "eye hemorrhage" }, | |
| { | |
| "mp_term_id": "MP:0001319", | |
| "mp_term_name": "irregularly shaped pupil" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012122", | |
| "mp_term_name": "abnormal iris transillumination" | |
| }, | |
| { "mp_term_id": "MP:0005544", "mp_term_name": "corneal deposits" }, | |
| { | |
| "mp_term_id": "MP:0005102", | |
| "mp_term_name": "abnormal iris pigmentation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006243", | |
| "mp_term_name": "impaired pupillary reflex" | |
| }, | |
| { "mp_term_id": "MP:0012121", "mp_term_name": "sclerocornea" }, | |
| { "mp_term_id": "MP:0005542", "mp_term_name": "corneal vascularization" }, | |
| { "mp_term_id": "MP:0005176", "mp_term_name": "eyelids fail to open" }, | |
| { | |
| "mp_term_id": "MP:0001340", | |
| "mp_term_name": "abnormal eyelid morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001322", | |
| "mp_term_name": "abnormal iris morphology" | |
| }, | |
| { "mp_term_id": "MP:0002750", "mp_term_name": "exophthalmos" }, | |
| { "mp_term_id": "MP:0002546", "mp_term_name": "mydriasis" } | |
| ], | |
| "phenotype_count": 14 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929293", | |
| "marker_symbol": "Cib2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001556", | |
| "mp_term_name": "increased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010087", | |
| "mp_term_name": "increased circulating fructosamine level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929293", | |
| "marker_symbol": "Cib2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Auditory Brain Stem Response" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| }, | |
| { "mp_term_id": "MP:0002102", "mp_term_name": "abnormal ear morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929293", | |
| "marker_symbol": "Cib2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929471", | |
| "marker_symbol": "Myoz1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Modified SHIRPA"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008528", "mp_term_name": "polycystic kidney" }, | |
| { "mp_term_id": "MP:0001756", "mp_term_name": "abnormal urination" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929471", | |
| "marker_symbol": "Myoz1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929646", | |
| "marker_symbol": "Pex3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Slit Lamp"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005542", "mp_term_name": "corneal vascularization" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929711", | |
| "marker_symbol": "Anapc7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929711", | |
| "marker_symbol": "Anapc7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929743", | |
| "marker_symbol": "Asb2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929743", | |
| "marker_symbol": "Asb2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003229", | |
| "mp_term_name": "abnormal vitelline vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000288", | |
| "mp_term_name": "abnormal pericardium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929813", | |
| "marker_symbol": "Cacna2d2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929813", | |
| "marker_symbol": "Cacna2d2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1929878", | |
| "marker_symbol": "Smoc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { "mp_term_id": "MP:0011496", "mp_term_name": "abnormal head size" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1930128", | |
| "marker_symbol": "Zc3h8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005568", | |
| "mp_term_name": "increased circulating total protein level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1930618", | |
| "marker_symbol": "Krit1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009806", | |
| "mp_term_name": "abnormal otic vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1930618", | |
| "marker_symbol": "Krit1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001691", "mp_term_name": "abnormal somite shape" }, | |
| { | |
| "mp_term_id": "MP:0002824", | |
| "mp_term_name": "abnormal chorioallantoic fusion" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001706", | |
| "mp_term_name": "abnormal left-right axis patterning" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001726", | |
| "mp_term_name": "abnormal allantois morphology" | |
| } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1930643", | |
| "marker_symbol": "Clcnkb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { | |
| "mp_term_id": "MP:0011874", | |
| "mp_term_name": "enlarged urinary bladder" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1930643", | |
| "marker_symbol": "Clcnkb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength", "Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1930801", | |
| "marker_symbol": "Spz1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1931249", | |
| "marker_symbol": "Slc35b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1931249", | |
| "marker_symbol": "Slc35b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1931838", | |
| "marker_symbol": "Dbn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "Dexa-scan analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1931838", | |
| "marker_symbol": "Dbn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1932075", | |
| "marker_symbol": "Agpat1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Urinalysis", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001759", | |
| "mp_term_name": "increased urine glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002959", | |
| "mp_term_name": "increased urine microalbumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003020", | |
| "mp_term_name": "decreased circulating chloride level" | |
| } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1933113", | |
| "marker_symbol": "Gpr146", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000745", "mp_term_name": "tremors" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1933126", | |
| "marker_symbol": "Cdk5rap3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1935145", | |
| "marker_symbol": "Mllt6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2135607", | |
| "marker_symbol": "Sirt1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Echo", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003921", | |
| "mp_term_name": "abnormal heart left ventricle morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004122", | |
| "mp_term_name": "abnormal sinus arrhythmia" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2135607", | |
| "marker_symbol": "Sirt1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000455", | |
| "mp_term_name": "abnormal maxilla morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004509", | |
| "mp_term_name": "abnormal pelvic girdle bone morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000149", | |
| "mp_term_name": "abnormal scapula morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2136171", | |
| "marker_symbol": "Aff4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2136335", | |
| "marker_symbol": "Klhl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Lung mechanics by forced oscillations" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2136335", | |
| "marker_symbol": "Klhl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2136335", | |
| "marker_symbol": "Klhl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2136335", | |
| "marker_symbol": "Klhl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004931", "mp_term_name": "enlarged epididymis" }, | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002631", | |
| "mp_term_name": "abnormal epididymis morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2137586", | |
| "marker_symbol": "Dtnbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005102", | |
| "mp_term_name": "abnormal iris pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2137586", | |
| "marker_symbol": "Dtnbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2138365", | |
| "marker_symbol": "Tmem237", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2138584", | |
| "marker_symbol": "Gigyf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2138648", | |
| "marker_symbol": "Serpinb10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2138648", | |
| "marker_symbol": "Serpinb10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2138828", | |
| "marker_symbol": "Eps8l2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { "mp_term_id": "MP:0001486", "mp_term_name": "abnormal startle reflex" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2138997", | |
| "marker_symbol": "Prom2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000579", "mp_term_name": "abnormal nail morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2139371", | |
| "marker_symbol": "Bahd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Immunophenotyping", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010851", | |
| "mp_term_name": "decreased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013511", | |
| "mp_term_name": "increased CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013514", | |
| "mp_term_name": "increased memory-marker CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008044", | |
| "mp_term_name": "increased NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008039", | |
| "mp_term_name": "increased NK T cell number" | |
| }, | |
| { "mp_term_id": "MP:0005015", "mp_term_name": "increased T cell number" } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2139447", | |
| "marker_symbol": "Galnt13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2140873", | |
| "marker_symbol": "Ttc28", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2140873", | |
| "marker_symbol": "Ttc28", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2140873", | |
| "marker_symbol": "Ttc28", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2140998", | |
| "marker_symbol": "Ube3c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Indirect Calorimetry", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011971", | |
| "mp_term_name": "increased circulating lactate dehydrogenase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004151", | |
| "mp_term_name": "decreased circulating iron level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010379", | |
| "mp_term_name": "decreased respiratory quotient" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2141439", | |
| "marker_symbol": "Fam71f2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2141439", | |
| "marker_symbol": "Fam71f2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001489", "mp_term_name": "decreased startle reflex" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2141847", | |
| "marker_symbol": "Phrf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2142227", | |
| "marker_symbol": "Lrrk1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Body Composition (DEXA lean/fat)", | |
| "X-ray" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0030610", "mp_term_name": "absent teeth" }, | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2142227", | |
| "marker_symbol": "Lrrk1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005012", | |
| "mp_term_name": "decreased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2142624", | |
| "marker_symbol": "Peds1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010096", "mp_term_name": "abnormal incisor color" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2142951", | |
| "marker_symbol": "Edc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011874", | |
| "mp_term_name": "enlarged urinary bladder" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2142951", | |
| "marker_symbol": "Edc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2142985", | |
| "marker_symbol": "Xylb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart weight/tibia length"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2144041", | |
| "marker_symbol": "Wsb2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005369", | |
| "top_level_mp_term_name": "muscle phenotype" | |
| }, | |
| "procedures": ["Echo"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005140", | |
| "mp_term_name": "decreased cardiac muscle contractility" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2144041", | |
| "marker_symbol": "Wsb2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2144474", | |
| "marker_symbol": "Ppp4r3b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2144474", | |
| "marker_symbol": "Ppp4r3b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2144475", | |
| "marker_symbol": "Usp32", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2144738", | |
| "marker_symbol": "Tedc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2144755", | |
| "marker_symbol": "Ankmy2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2145316", | |
| "marker_symbol": "Txndc5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2145316", | |
| "marker_symbol": "Txndc5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2145900", | |
| "marker_symbol": "Fam83h", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2145950", | |
| "marker_symbol": "Scrib", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2145950", | |
| "marker_symbol": "Scrib", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2146034", | |
| "marker_symbol": "Krt72", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000538", | |
| "mp_term_name": "abnormal urinary bladder morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2146034", | |
| "marker_symbol": "Krt72", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000160", "mp_term_name": "kyphosis" }, | |
| { "mp_term_id": "MP:0004174", "mp_term_name": "abnormal spine curvature" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2146159", | |
| "marker_symbol": "Alg10b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2146995", | |
| "marker_symbol": "Mpig6b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2147077", | |
| "marker_symbol": "Pkdcc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2147134", | |
| "marker_symbol": "Fbxo11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2147658", | |
| "marker_symbol": "Afap1l2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2147810", | |
| "marker_symbol": "Tmem132a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Morphology Embryo E12.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2149839", | |
| "marker_symbol": "Fam126a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000618", "mp_term_name": "small salivary gland" }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000613", | |
| "mp_term_name": "abnormal salivary gland morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2149839", | |
| "marker_symbol": "Fam126a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2150016", | |
| "marker_symbol": "Spred1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2150016", | |
| "marker_symbol": "Spred1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0008039", | |
| "mp_term_name": "increased NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013523", | |
| "mp_term_name": "increased memory-marker CD4-positive NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010168", | |
| "mp_term_name": "increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010850", | |
| "mp_term_name": "increased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013520", | |
| "mp_term_name": "increased CD4-positive NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013772", | |
| "mp_term_name": "increased effector memory T-helper cell number" | |
| } | |
| ], | |
| "phenotype_count": 15 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2150016", | |
| "marker_symbol": "Spred1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004613", | |
| "mp_term_name": "fusion of vertebral arches" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000137", | |
| "mp_term_name": "abnormal vertebrae morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005270", | |
| "mp_term_name": "abnormal zygomatic bone morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004599", | |
| "mp_term_name": "abnormal vertebral arch morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000455", | |
| "mp_term_name": "abnormal maxilla morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000458", | |
| "mp_term_name": "abnormal mandible morphology" | |
| }, | |
| { "mp_term_id": "MP:0004609", "mp_term_name": "vertebral fusion" } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2150016", | |
| "marker_symbol": "Spred1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011239", | |
| "mp_term_name": "abnormal skin coloration" | |
| }, | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2150037", | |
| "marker_symbol": "Mta1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Dysmorphology", "X-Ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002111", | |
| "mp_term_name": "abnormal tail morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001539", | |
| "mp_term_name": "decreased caudal vertebrae number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2151152", | |
| "marker_symbol": "Baz2a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2152414", | |
| "marker_symbol": "Ipo7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2152414", | |
| "marker_symbol": "Ipo7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2152835", | |
| "marker_symbol": "Asb7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003917", "mp_term_name": "increased kidney weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2152835", | |
| "marker_symbol": "Asb7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2152835", | |
| "marker_symbol": "Asb7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003917", "mp_term_name": "increased kidney weight" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2152835", | |
| "marker_symbol": "Asb7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Echo"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010574", "mp_term_name": "dilated aorta" }, | |
| { | |
| "mp_term_id": "MP:0005599", | |
| "mp_term_name": "increased cardiac muscle contractility" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2152835", | |
| "marker_symbol": "Asb7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping", | |
| "Hematology" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008079", | |
| "mp_term_name": "decreased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153063", | |
| "marker_symbol": "Parvb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Haematology", "FACs Analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| }, | |
| { "mp_term_id": "MP:0005018", "mp_term_name": "decreased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0000322", | |
| "mp_term_name": "increased granulocyte number" | |
| }, | |
| { "mp_term_id": "MP:0008045", "mp_term_name": "decreased NK cell number" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153072", | |
| "marker_symbol": "Trim37", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005292", | |
| "mp_term_name": "improved glucose tolerance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153072", | |
| "marker_symbol": "Trim37", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153072", | |
| "marker_symbol": "Trim37", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153463", | |
| "marker_symbol": "Rxfp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009552", | |
| "mp_term_name": "urinary bladder obstruction" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153463", | |
| "marker_symbol": "Rxfp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153463", | |
| "marker_symbol": "Rxfp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Modified SHIRPA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153463", | |
| "marker_symbol": "Rxfp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005564", | |
| "mp_term_name": "increased hemoglobin content" | |
| }, | |
| { "mp_term_id": "MP:0002608", "mp_term_name": "increased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0003131", | |
| "mp_term_name": "increased erythrocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2153608", | |
| "marker_symbol": "Ube2j2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2154580", | |
| "marker_symbol": "Ube4a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2156864", | |
| "marker_symbol": "Phf5a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2156864", | |
| "marker_symbol": "Phf5a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2176740", | |
| "marker_symbol": "Helq", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2176740", | |
| "marker_symbol": "Helq", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2177178", | |
| "marker_symbol": "Dicer1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2179061", | |
| "marker_symbol": "Plxna4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2179061", | |
| "marker_symbol": "Plxna4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000601", "mp_term_name": "small liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2179061", | |
| "marker_symbol": "Plxna4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2179061", | |
| "marker_symbol": "Plxna4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0006243", | |
| "mp_term_name": "impaired pupillary reflex" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2179061", | |
| "marker_symbol": "Plxna4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2179288", | |
| "marker_symbol": "Rttn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2181659", | |
| "marker_symbol": "Tox", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2182465", | |
| "marker_symbol": "Vrk3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2182465", | |
| "marker_symbol": "Vrk3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2182543", | |
| "marker_symbol": "Grhl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { "mp_term_id": "MP:0000914", "mp_term_name": "exencephaly" }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2182543", | |
| "marker_symbol": "Grhl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E9.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2182928", | |
| "marker_symbol": "Adgrf5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2182928", | |
| "marker_symbol": "Adgrf5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2183426", | |
| "marker_symbol": "Rspo1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011960", | |
| "mp_term_name": "abnormal eye anterior chamber depth" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003731", | |
| "mp_term_name": "abnormal retina outer nuclear layer morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011965", | |
| "mp_term_name": "decreased total retina thickness" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384583", | |
| "marker_symbol": "Zfp280d", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384589", | |
| "marker_symbol": "Herc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384589", | |
| "marker_symbol": "Herc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384589", | |
| "marker_symbol": "Herc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013025", | |
| "mp_term_name": "increased Ly6C low monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013022", | |
| "mp_term_name": "increased Ly6C high monocyte number" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384589", | |
| "marker_symbol": "Herc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013025", | |
| "mp_term_name": "increased Ly6C low monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013022", | |
| "mp_term_name": "increased Ly6C high monocyte number" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384875", | |
| "marker_symbol": "Cdk5rap2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384875", | |
| "marker_symbol": "Cdk5rap2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Haematology test"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384936", | |
| "marker_symbol": "Spns2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Open Field", | |
| "Modified SHIRPA" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001512", "mp_term_name": "trunk curl" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { "mp_term_id": "MP:0006358", "mp_term_name": "absent pinna reflex" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2384936", | |
| "marker_symbol": "Spns2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Dysmorphology", | |
| "Slit Lamp", | |
| "Modified SHIRPA" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005287", "mp_term_name": "narrow eye opening" }, | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { "mp_term_id": "MP:0001349", "mp_term_name": "excessive tearing" }, | |
| { | |
| "mp_term_id": "MP:0001324", | |
| "mp_term_name": "abnormal eye pigmentation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003671", | |
| "mp_term_name": "abnormal eyelid aperture" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001317", | |
| "mp_term_name": "abnormal pupil morphology" | |
| }, | |
| { "mp_term_id": "MP:0005542", "mp_term_name": "corneal vascularization" }, | |
| { "mp_term_id": "MP:0002697", "mp_term_name": "abnormal eye size" }, | |
| { | |
| "mp_term_id": "MP:0001322", | |
| "mp_term_name": "abnormal iris morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 11 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2385054", | |
| "marker_symbol": "Pex6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2385110", | |
| "marker_symbol": "Aph1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2385110", | |
| "marker_symbol": "Aph1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2385213", | |
| "marker_symbol": "Pdik1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2385599", | |
| "marker_symbol": "Gtpbp10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005564", | |
| "mp_term_name": "increased hemoglobin content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005641", | |
| "mp_term_name": "increased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387006", | |
| "marker_symbol": "Gipc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001489", "mp_term_name": "decreased startle reflex" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387203", | |
| "marker_symbol": "Ppat", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0006243", | |
| "mp_term_name": "impaired pupillary reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001415", | |
| "mp_term_name": "increased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387357", | |
| "marker_symbol": "Wac", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Whole blood peripheral blood leukocyte immunophenotyping"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005012", | |
| "mp_term_name": "decreased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013025", | |
| "mp_term_name": "increased Ly6C low monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387367", | |
| "marker_symbol": "Rbm45", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387367", | |
| "marker_symbol": "Rbm45", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387613", | |
| "marker_symbol": "Erlin1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000470", | |
| "mp_term_name": "abnormal stomach morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387613", | |
| "marker_symbol": "Erlin1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387613", | |
| "marker_symbol": "Erlin1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2387642", | |
| "marker_symbol": "Cxcl17", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2389174", | |
| "marker_symbol": "Lrrtm2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2389174", | |
| "marker_symbol": "Lrrtm2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001175", "mp_term_name": "abnormal lung morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2441675", | |
| "marker_symbol": "Pgbd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011874", "mp_term_name": "enlarged urinary bladder" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2441675", | |
| "marker_symbol": "Pgbd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2441675", | |
| "marker_symbol": "Pgbd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442161", | |
| "marker_symbol": "Fam221a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442161", | |
| "marker_symbol": "Fam221a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping", | |
| "Hematology" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013436", | |
| "mp_term_name": "increased CD8-positive, naive alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442190", | |
| "marker_symbol": "Camk1d", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442261", | |
| "marker_symbol": "Cgas", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle&PPI"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442261", | |
| "marker_symbol": "Cgas", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442473", | |
| "marker_symbol": "Rhbdf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002896", | |
| "mp_term_name": "abnormal bone mineralization" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442473", | |
| "marker_symbol": "Rhbdf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology", "FACs Analysis"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005014", "mp_term_name": "increased B cell number" }, | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { "mp_term_id": "MP:0005017", "mp_term_name": "decreased B cell number" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442473", | |
| "marker_symbol": "Rhbdf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002098", | |
| "mp_term_name": "abnormal vibrissa morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001510", | |
| "mp_term_name": "abnormal coat appearance" | |
| }, | |
| { "mp_term_id": "MP:0000414", "mp_term_name": "alopecia" }, | |
| { "mp_term_id": "MP:0002073", "mp_term_name": "abnormal hair growth" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442557", | |
| "marker_symbol": "Frmd5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["DEXA", "Body Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001260", "mp_term_name": "increased body weight" }, | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442557", | |
| "marker_symbol": "Frmd5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442609", | |
| "marker_symbol": "Rnf43", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442609", | |
| "marker_symbol": "Rnf43", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442707", | |
| "marker_symbol": "Tmem72", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001566", | |
| "mp_term_name": "increased circulating phosphate level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005566", | |
| "mp_term_name": "decreased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442707", | |
| "marker_symbol": "Tmem72", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442707", | |
| "marker_symbol": "Tmem72", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005564", | |
| "mp_term_name": "increased hemoglobin content" | |
| }, | |
| { "mp_term_id": "MP:0002608", "mp_term_name": "increased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0003131", | |
| "mp_term_name": "increased erythrocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442827", | |
| "marker_symbol": "Tbc1d32", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442827", | |
| "marker_symbol": "Tbc1d32", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442827", | |
| "marker_symbol": "Tbc1d32", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2442934", | |
| "marker_symbol": "Minar2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443014", | |
| "marker_symbol": "Ino80c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002111", "mp_term_name": "abnormal tail morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443162", | |
| "marker_symbol": "Uggt1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443162", | |
| "marker_symbol": "Uggt1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001614", | |
| "mp_term_name": "abnormal blood vessel morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003229", | |
| "mp_term_name": "abnormal vitelline vasculature morphology" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443207", | |
| "marker_symbol": "Plekhm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443317", | |
| "marker_symbol": "Tmc7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443324", | |
| "marker_symbol": "Fbxw16", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000706", "mp_term_name": "small thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443327", | |
| "marker_symbol": "Fa2h", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443369", | |
| "marker_symbol": "Fgd5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443410", | |
| "marker_symbol": "Fndc9", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443417", | |
| "marker_symbol": "Tmem74", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0011874", "mp_term_name": "enlarged urinary bladder" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443417", | |
| "marker_symbol": "Tmem74", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { "mp_term_id": "MP:0000706", "mp_term_name": "small thymus" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443432", | |
| "marker_symbol": "Foxj3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443432", | |
| "marker_symbol": "Foxj3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443480", | |
| "marker_symbol": "Setx", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011965", | |
| "mp_term_name": "decreased total retina thickness" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443554", | |
| "marker_symbol": "Hook3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443554", | |
| "marker_symbol": "Hook3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443564", | |
| "marker_symbol": "Ambra1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E18.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { "mp_term_id": "MP:0002080", "mp_term_name": "prenatal lethality" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443597", | |
| "marker_symbol": "Tmem203", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2443963", | |
| "marker_symbol": "Cadps2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000613", | |
| "mp_term_name": "abnormal salivary gland morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001944", | |
| "mp_term_name": "abnormal pancreas morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444031", | |
| "marker_symbol": "Alg6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011874", "mp_term_name": "enlarged urinary bladder" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444031", | |
| "marker_symbol": "Alg6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E14.5-E15.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013294", | |
| "mp_term_name": "prenatal lethality prior to heart atrial septation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444110", | |
| "marker_symbol": "Sgms1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444121", | |
| "marker_symbol": "Tanc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444155", | |
| "marker_symbol": "Nmnat2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444169", | |
| "marker_symbol": "Lmod3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444169", | |
| "marker_symbol": "Lmod3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444169", | |
| "marker_symbol": "Lmod3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000639", | |
| "mp_term_name": "abnormal adrenal gland morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444210", | |
| "marker_symbol": "Nr1d1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Echo"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003393", | |
| "mp_term_name": "decreased cardiac output" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444210", | |
| "marker_symbol": "Nr1d1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Open Field - centre start", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001491", | |
| "mp_term_name": "unresponsive to tactile stimuli" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002757", | |
| "mp_term_name": "decreased vertical activity" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444236", | |
| "marker_symbol": "Ubn2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0009263", "mp_term_name": "abnormal eyelid fusion" }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444273", | |
| "marker_symbol": "Dennd5b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444273", | |
| "marker_symbol": "Dennd5b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010068", | |
| "mp_term_name": "decreased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444310", | |
| "marker_symbol": "Fsd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444310", | |
| "marker_symbol": "Fsd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { "mp_term_id": "MP:0003642", "mp_term_name": "absent seminal vesicle" }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444341", | |
| "marker_symbol": "Phf8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444486", | |
| "marker_symbol": "Tarsl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444486", | |
| "marker_symbol": "Tarsl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444584", | |
| "marker_symbol": "Mysm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444584", | |
| "marker_symbol": "Mysm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003019", | |
| "mp_term_name": "increased circulating chloride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000183", | |
| "mp_term_name": "decreased circulating LDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002944", | |
| "mp_term_name": "increased lactate dehydrogenase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001566", | |
| "mp_term_name": "increased circulating phosphate level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008805", | |
| "mp_term_name": "decreased circulating amylase level" | |
| } | |
| ], | |
| "phenotype_count": 12 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444584", | |
| "marker_symbol": "Mysm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["X-Ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444584", | |
| "marker_symbol": "Mysm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Haematology", "Immunoglobulin", "FACs Analysis"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002492", "mp_term_name": "decreased IgE level" }, | |
| { "mp_term_id": "MP:0008502", "mp_term_name": "increased IgG3 level" }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008211", | |
| "mp_term_name": "decreased mature B cell number" | |
| }, | |
| { "mp_term_id": "MP:0005017", "mp_term_name": "decreased B cell number" }, | |
| { "mp_term_id": "MP:0008501", "mp_term_name": "increased IgG2b level" }, | |
| { "mp_term_id": "MP:0005015", "mp_term_name": "increased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000322", | |
| "mp_term_name": "increased granulocyte number" | |
| } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444631", | |
| "marker_symbol": "4932438A13Rik", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005559", | |
| "mp_term_name": "increased circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444631", | |
| "marker_symbol": "4932438A13Rik", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444631", | |
| "marker_symbol": "4932438A13Rik", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Heart Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001914", "mp_term_name": "hemorrhage" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444631", | |
| "marker_symbol": "4932438A13Rik", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003717", "mp_term_name": "pallor" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444639", | |
| "marker_symbol": "Fbxo38", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000601", "mp_term_name": "small liver" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444639", | |
| "marker_symbol": "Fbxo38", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444639", | |
| "marker_symbol": "Fbxo38", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444639", | |
| "marker_symbol": "Fbxo38", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444772", | |
| "marker_symbol": "Zhx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001257", "mp_term_name": "increased body length" }, | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444772", | |
| "marker_symbol": "Zhx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004357", "mp_term_name": "long tibia" }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000062", | |
| "mp_term_name": "increased bone mineral density" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444798", | |
| "marker_symbol": "Atad2b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004357", "mp_term_name": "long tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444798", | |
| "marker_symbol": "Atad2b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Immunophenotyping"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008040", | |
| "mp_term_name": "decreased NK T cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2444800", | |
| "marker_symbol": "Prss35", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2445053", | |
| "marker_symbol": "Ccbe1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Morphology Placenta E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2445066", | |
| "marker_symbol": "Hmbox1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2445066", | |
| "marker_symbol": "Hmbox1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2445066", | |
| "marker_symbol": "Hmbox1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2445066", | |
| "marker_symbol": "Hmbox1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2445066", | |
| "marker_symbol": "Hmbox1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2445066", | |
| "marker_symbol": "Hmbox1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2446244", | |
| "marker_symbol": "Setd1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Dexa-scan analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000062", | |
| "mp_term_name": "increased bone mineral density" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2447063", | |
| "marker_symbol": "Tenm4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2447063", | |
| "marker_symbol": "Tenm4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004953", "mp_term_name": "decreased spleen weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2447670", | |
| "marker_symbol": "Mgrn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Auditory Brain Stem Response" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| }, | |
| { "mp_term_id": "MP:0002102", "mp_term_name": "abnormal ear morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2447670", | |
| "marker_symbol": "Mgrn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2447670", | |
| "marker_symbol": "Mgrn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010393", | |
| "mp_term_name": "shortened QRS complex duration" | |
| }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2447763", | |
| "marker_symbol": "Dnd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2447794", | |
| "marker_symbol": "Sfmbt2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2447813", | |
| "marker_symbol": "Serac1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2448481", | |
| "marker_symbol": "Mgst2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2448481", | |
| "marker_symbol": "Mgst2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2448481", | |
| "marker_symbol": "Mgst2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2448562", | |
| "marker_symbol": "Adnp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2448567", | |
| "marker_symbol": "Chd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2651811", | |
| "marker_symbol": "Tph2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2654070", | |
| "marker_symbol": "Sox21", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2655562", | |
| "marker_symbol": "Adgrl4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000601", "mp_term_name": "small liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2655562", | |
| "marker_symbol": "Adgrl4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2659021", | |
| "marker_symbol": "Phactr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2659021", | |
| "marker_symbol": "Phactr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2661234", | |
| "marker_symbol": "Prss33", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009141", | |
| "mp_term_name": "increased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2661430", | |
| "marker_symbol": "Kbtbd8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2669796", | |
| "marker_symbol": "Rtn4rl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000774", "mp_term_name": "decreased brain size" }, | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2670964", | |
| "marker_symbol": "Tent5a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Indirect Calorimetry", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010379", | |
| "mp_term_name": "decreased respiratory quotient" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2672118", | |
| "marker_symbol": "Col27a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2672118", | |
| "marker_symbol": "Col27a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Placenta E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2672118", | |
| "marker_symbol": "Col27a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2676556", | |
| "marker_symbol": "Akap13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2677061", | |
| "marker_symbol": "Dagla", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003641", "mp_term_name": "small lung" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2677270", | |
| "marker_symbol": "Pdzd8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008806", | |
| "mp_term_name": "increased circulating amylase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001566", | |
| "mp_term_name": "increased circulating phosphate level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005565", | |
| "mp_term_name": "increased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2677270", | |
| "marker_symbol": "Pdzd8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002098", | |
| "mp_term_name": "abnormal vibrissa morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2679716", | |
| "marker_symbol": "Fam205c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2679716", | |
| "marker_symbol": "Fam205c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008078", | |
| "mp_term_name": "increased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0013436", | |
| "mp_term_name": "increased CD8-positive, naive alpha-beta T cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2679720", | |
| "marker_symbol": "Vsig4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Open Field - centre start", | |
| "Light-Dark Test", | |
| "Sleep Wake" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011396", "mp_term_name": "abnormal sleep behavior" }, | |
| { | |
| "mp_term_id": "MP:0002574", | |
| "mp_term_name": "increased vertical activity" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2681869", | |
| "marker_symbol": "Cep135", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2681869", | |
| "marker_symbol": "Cep135", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2682064", | |
| "marker_symbol": "Ift172", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2682064", | |
| "marker_symbol": "Ift172", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2682295", | |
| "marker_symbol": "Tent4a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2682295", | |
| "marker_symbol": "Tent4a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2682295", | |
| "marker_symbol": "Tent4a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005084", | |
| "mp_term_name": "abnormal gallbladder morphology" | |
| }, | |
| { "mp_term_id": "MP:0009342", "mp_term_name": "enlarged gallbladder" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2682314", | |
| "marker_symbol": "Zc3h4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0001186", | |
| "top_level_mp_term_name": "pigmentation phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2682314", | |
| "marker_symbol": "Zc3h4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002965", | |
| "mp_term_name": "increased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000194", | |
| "mp_term_name": "increased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2684313", | |
| "marker_symbol": "Togaram1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2684927", | |
| "marker_symbol": "Cenpj", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009199", | |
| "mp_term_name": "abnormal external male genitalia morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003126", | |
| "mp_term_name": "abnormal external female genitalia morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685014", | |
| "marker_symbol": "Asphd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Echo"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685014", | |
| "marker_symbol": "Asphd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685120", | |
| "marker_symbol": "Prss47", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685233", | |
| "marker_symbol": "Ptchd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005553", | |
| "mp_term_name": "increased circulating creatinine level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685325", | |
| "marker_symbol": "Hspb6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685387", | |
| "marker_symbol": "Atp13a3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685419", | |
| "marker_symbol": "Ajap1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003019", | |
| "mp_term_name": "increased circulating chloride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005568", | |
| "mp_term_name": "increased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005633", | |
| "mp_term_name": "increased circulating sodium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685483", | |
| "marker_symbol": "Gsg1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685483", | |
| "marker_symbol": "Gsg1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685530", | |
| "marker_symbol": "Colca2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013278", | |
| "mp_term_name": "decreased fasting circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685530", | |
| "marker_symbol": "Colca2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Grip Strength", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { "mp_term_id": "MP:0001489", "mp_term_name": "decreased startle reflex" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685728", | |
| "marker_symbol": "Spata22", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Fertility of Homozygous Knock-out Mice" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { "mp_term_id": "MP:0004931", "mp_term_name": "enlarged epididymis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685728", | |
| "marker_symbol": "Spata22", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685953", | |
| "marker_symbol": "Cib3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002102", "mp_term_name": "abnormal ear morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685953", | |
| "marker_symbol": "Cib3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2685995", | |
| "marker_symbol": "Taar8b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2686277", | |
| "marker_symbol": "Iglon5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2686277", | |
| "marker_symbol": "Iglon5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:2686277", | |
| "marker_symbol": "Iglon5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3036247", | |
| "marker_symbol": "Lmtk2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Electrocardiogram (ECG)" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3036280", | |
| "marker_symbol": "Duox2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3036280", | |
| "marker_symbol": "Duox2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000223", | |
| "mp_term_name": "decreased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3036280", | |
| "marker_symbol": "Duox2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000223", | |
| "mp_term_name": "decreased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3039629", | |
| "marker_symbol": "Slc17a8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3045303", | |
| "marker_symbol": "Mamld1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3045303", | |
| "marker_symbol": "Mamld1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Indirect Calorimetry", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005278", | |
| "mp_term_name": "abnormal cholesterol homeostasis" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010379", | |
| "mp_term_name": "decreased respiratory quotient" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3045303", | |
| "marker_symbol": "Mamld1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3045303", | |
| "marker_symbol": "Mamld1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3505704", | |
| "marker_symbol": "Fbxw18", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003019", | |
| "mp_term_name": "increased circulating chloride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005633", | |
| "mp_term_name": "increased circulating sodium level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3505704", | |
| "marker_symbol": "Fbxw18", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3505704", | |
| "marker_symbol": "Fbxw18", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3512628", | |
| "marker_symbol": "Cbx6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000558", | |
| "mp_term_name": "abnormal tibia morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3512628", | |
| "marker_symbol": "Cbx6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008935", | |
| "mp_term_name": "decreased mean platelet volume" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3528583", | |
| "marker_symbol": "Rnase11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0009552", | |
| "mp_term_name": "urinary bladder obstruction" | |
| }, | |
| { "mp_term_id": "MP:0003918", "mp_term_name": "decreased kidney weight" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3582052", | |
| "marker_symbol": "Slc51b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3583900", | |
| "marker_symbol": "Elmod1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Open-field", | |
| "Grip Strength", | |
| "Slit Lamp", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Open Field", | |
| "Modified SHIRPA", | |
| "Acoustic Startle&PPI", | |
| "Grip-Strength" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001488", | |
| "mp_term_name": "increased startle reflex" | |
| }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0005316", | |
| "mp_term_name": "abnormal response to tactile stimuli" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { | |
| "mp_term_id": "MP:0003313", | |
| "mp_term_name": "abnormal locomotor activation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001392", | |
| "mp_term_name": "abnormal locomotor behavior" | |
| }, | |
| { "mp_term_id": "MP:0001406", "mp_term_name": "abnormal gait" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" }, | |
| { | |
| "mp_term_id": "MP:0006243", | |
| "mp_term_name": "impaired pupillary reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0001410", "mp_term_name": "head bobbing" }, | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { "mp_term_id": "MP:0001512", "mp_term_name": "trunk curl" }, | |
| { "mp_term_id": "MP:0000745", "mp_term_name": "tremors" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0001486", "mp_term_name": "abnormal startle reflex" } | |
| ], | |
| "phenotype_count": 17 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3588194", | |
| "marker_symbol": "Prdm14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field - centre start"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3588194", | |
| "marker_symbol": "Prdm14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Immunophenotyping"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013772", | |
| "mp_term_name": "increased effector memory T-helper cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3588194", | |
| "marker_symbol": "Prdm14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3588194", | |
| "marker_symbol": "Prdm14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0000150", "mp_term_name": "abnormal rib morphology" }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3603204", | |
| "marker_symbol": "Piezo1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3603204", | |
| "marker_symbol": "Piezo1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3603204", | |
| "marker_symbol": "Piezo1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3605549", | |
| "marker_symbol": "Adgb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| }, | |
| { "mp_term_id": "MP:0001891", "mp_term_name": "hydrocephaly" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3605549", | |
| "marker_symbol": "Adgb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005369", | |
| "top_level_mp_term_name": "muscle phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004818", | |
| "mp_term_name": "increased skeletal muscle mass" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3605549", | |
| "marker_symbol": "Adgb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Fertility of Homozygous Knock-out Mice" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3606062", | |
| "marker_symbol": "Pcyox1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3607779", | |
| "marker_symbol": "Tmem145", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001489", "mp_term_name": "decreased startle reflex" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3609239", | |
| "marker_symbol": "Mrap2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Insulin Blood Level", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002079", | |
| "mp_term_name": "increased circulating insulin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000194", | |
| "mp_term_name": "increased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3609239", | |
| "marker_symbol": "Mrap2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3618859", | |
| "marker_symbol": "Fam163a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3619440", | |
| "marker_symbol": "Mir96", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3619440", | |
| "marker_symbol": "Mir96", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3619440", | |
| "marker_symbol": "Mir96", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3641657", | |
| "marker_symbol": "Gm10800", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3642684", | |
| "marker_symbol": "Cep85l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3643902", | |
| "marker_symbol": "Gnptab", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3643902", | |
| "marker_symbol": "Gnptab", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3646469", | |
| "marker_symbol": "Agbl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3646469", | |
| "marker_symbol": "Agbl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004222", "mp_term_name": "iris synechia" }, | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001307", "mp_term_name": "fused cornea and lens" }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3648074", | |
| "marker_symbol": "Tmem240", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3648807", | |
| "marker_symbol": "Mcidas", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3650152", | |
| "marker_symbol": "Trabd2b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005565", | |
| "mp_term_name": "increased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3650152", | |
| "marker_symbol": "Trabd2b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Echo"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002953", "mp_term_name": "thick ventricular wall" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:3650217", | |
| "marker_symbol": "Btbd18", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:5670665", | |
| "marker_symbol": "Cpgi5563", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:87914", | |
| "marker_symbol": "Aspa", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:87914", | |
| "marker_symbol": "Aspa", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:87930", | |
| "marker_symbol": "Adk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004882", "mp_term_name": "enlarged lung" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:87930", | |
| "marker_symbol": "Adk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004174", "mp_term_name": "abnormal spine curvature" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:87930", | |
| "marker_symbol": "Adk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88105", | |
| "marker_symbol": "Atp1a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88180", | |
| "marker_symbol": "Bmp4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88180", | |
| "marker_symbol": "Bmp4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001672", | |
| "mp_term_name": "abnormal embryo development" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001726", | |
| "mp_term_name": "abnormal allantois morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88180", | |
| "marker_symbol": "Bmp4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength", "Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88182", | |
| "marker_symbol": "Bmp6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88248", | |
| "marker_symbol": "Calb1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Echo"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005599", | |
| "mp_term_name": "increased cardiac muscle contractility" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0003921", | |
| "mp_term_name": "abnormal heart left ventricle morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88294", | |
| "marker_symbol": "Cacna1s", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5", | |
| "Plasma Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| }, | |
| { "mp_term_id": "MP:0001575", "mp_term_name": "cyanosis" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88294", | |
| "marker_symbol": "Cacna1s", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88295", | |
| "marker_symbol": "Cacna2d1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Fear Conditioning", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009453", | |
| "mp_term_name": "enhanced contextual conditioning behavior" | |
| }, | |
| { | |
| "mp_term_id": "MP:0020420", | |
| "mp_term_name": "abnormal freezing behavior" | |
| }, | |
| { | |
| "mp_term_id": "MP:0020421", | |
| "mp_term_name": "increased freezing behavior" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88295", | |
| "marker_symbol": "Cacna2d1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88314", | |
| "marker_symbol": "Ccnd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { "mp_term_id": "MP:0001512", "mp_term_name": "trunk curl" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88314", | |
| "marker_symbol": "Ccnd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88326", | |
| "marker_symbol": "Cd27", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88326", | |
| "marker_symbol": "Cd27", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88326", | |
| "marker_symbol": "Cd27", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88357", | |
| "marker_symbol": "Cdk4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88393", | |
| "marker_symbol": "Chd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010068", | |
| "mp_term_name": "decreased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88393", | |
| "marker_symbol": "Chd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88407", | |
| "marker_symbol": "Ckb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008935", | |
| "mp_term_name": "decreased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88407", | |
| "marker_symbol": "Ckb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002098", | |
| "mp_term_name": "abnormal vibrissa morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88451", | |
| "marker_symbol": "Col18a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005102", | |
| "mp_term_name": "abnormal iris pigmentation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001319", | |
| "mp_term_name": "irregularly shaped pupil" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006241", | |
| "mp_term_name": "abnormal placement of pupils" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88466", | |
| "marker_symbol": "Col9a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000558", | |
| "mp_term_name": "abnormal tibia morphology" | |
| }, | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0000552", | |
| "mp_term_name": "abnormal radius morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000559", | |
| "mp_term_name": "abnormal femur morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005296", | |
| "mp_term_name": "abnormal humerus morphology" | |
| }, | |
| { "mp_term_id": "MP:0005108", "mp_term_name": "abnormal ulna morphology" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88468", | |
| "marker_symbol": "Col1a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88468", | |
| "marker_symbol": "Col1a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008805", | |
| "mp_term_name": "decreased circulating amylase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005566", | |
| "mp_term_name": "decreased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88468", | |
| "marker_symbol": "Col1a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008935", | |
| "mp_term_name": "decreased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012362", | |
| "mp_term_name": "increased large unstained cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88470", | |
| "marker_symbol": "Comt", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001392", | |
| "mp_term_name": "abnormal locomotor behavior" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88547", | |
| "marker_symbol": "Csnk2a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { | |
| "mp_term_id": "MP:0002574", | |
| "mp_term_name": "increased vertical activity" | |
| }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88586", | |
| "marker_symbol": "Cyp17a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002834", "mp_term_name": "decreased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88586", | |
| "marker_symbol": "Cyp17a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001529", "mp_term_name": "abnormal vocalization" }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88587", | |
| "marker_symbol": "Cyp19a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002965", | |
| "mp_term_name": "increased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002966", | |
| "mp_term_name": "decreased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005565", | |
| "mp_term_name": "increased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88587", | |
| "marker_symbol": "Cyp19a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001363", | |
| "mp_term_name": "increased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0000745", "mp_term_name": "tremors" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0001406", "mp_term_name": "abnormal gait" }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:88594", | |
| "marker_symbol": "Cyp27a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005292", | |
| "mp_term_name": "improved glucose tolerance" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:893578", | |
| "marker_symbol": "Scarb1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:893578", | |
| "marker_symbol": "Scarb1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:893578", | |
| "marker_symbol": "Scarb1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:894332", | |
| "marker_symbol": "Ebf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011495", "mp_term_name": "abnormal head shape" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:894332", | |
| "marker_symbol": "Ebf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:894332", | |
| "marker_symbol": "Ebf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:894649", | |
| "marker_symbol": "Ppfibp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:894649", | |
| "marker_symbol": "Ppfibp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:894679", | |
| "marker_symbol": "Bach2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:894686", | |
| "marker_symbol": "Col9a3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:894686", | |
| "marker_symbol": "Col9a3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:91860", | |
| "marker_symbol": "Dcaf8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:94909", | |
| "marker_symbol": "Dmd", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:94909", | |
| "marker_symbol": "Dmd", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005568", | |
| "mp_term_name": "increased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002965", | |
| "mp_term_name": "increased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:94909", | |
| "marker_symbol": "Dmd", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95275", | |
| "marker_symbol": "Ebf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95275", | |
| "marker_symbol": "Ebf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95457", | |
| "marker_symbol": "Mecom", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95457", | |
| "marker_symbol": "Mecom", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95457", | |
| "marker_symbol": "Mecom", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle&PPI", "Modified SHIRPA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001488", | |
| "mp_term_name": "increased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003313", | |
| "mp_term_name": "abnormal locomotor activation" | |
| }, | |
| { "mp_term_id": "MP:0001513", "mp_term_name": "limb grasping" }, | |
| { "mp_term_id": "MP:0001486", "mp_term_name": "abnormal startle reflex" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95482", | |
| "marker_symbol": "Fah", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000601", "mp_term_name": "small liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95482", | |
| "marker_symbol": "Fah", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95482", | |
| "marker_symbol": "Fah", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95482", | |
| "marker_symbol": "Fah", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95490", | |
| "marker_symbol": "Fbn2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95559", | |
| "marker_symbol": "Flt3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95568", | |
| "marker_symbol": "Folr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95662", | |
| "marker_symbol": "Gata2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95667", | |
| "marker_symbol": "Gbx1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-Ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000564", "mp_term_name": "syndactyly" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95689", | |
| "marker_symbol": "Gdf6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95689", | |
| "marker_symbol": "Gdf6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95707", | |
| "marker_symbol": "Gh", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength", "Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95707", | |
| "marker_symbol": "Gh", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005631", "mp_term_name": "decreased lung weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95707", | |
| "marker_symbol": "Gh", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95709", | |
| "marker_symbol": "Ghrh", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95710", | |
| "marker_symbol": "Ghrhr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95710", | |
| "marker_symbol": "Ghrhr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Light-Dark Test", | |
| "Open Field - centre start", | |
| "Grip Strength", | |
| "Sleep Wake" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0002757", | |
| "mp_term_name": "decreased vertical activity" | |
| }, | |
| { "mp_term_id": "MP:0011396", "mp_term_name": "abnormal sleep behavior" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95710", | |
| "marker_symbol": "Ghrhr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95712", | |
| "marker_symbol": "Gpr83", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95721", | |
| "marker_symbol": "Gjb3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95770", | |
| "marker_symbol": "Gna15", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95775", | |
| "marker_symbol": "Gnao1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005012", | |
| "mp_term_name": "decreased eosinophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95775", | |
| "marker_symbol": "Gnao1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95792", | |
| "marker_symbol": "Got2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:95792", | |
| "marker_symbol": "Got2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003229", | |
| "mp_term_name": "abnormal vitelline vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001718", | |
| "mp_term_name": "abnormal visceral yolk sac morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96398", | |
| "marker_symbol": "Id3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96398", | |
| "marker_symbol": "Id3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96412", | |
| "marker_symbol": "Ide", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Dysmorphology", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000455", | |
| "mp_term_name": "abnormal maxilla morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005358", | |
| "mp_term_name": "abnormal incisor morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96412", | |
| "marker_symbol": "Ide", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002074", "mp_term_name": "abnormal hair texture" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96615", | |
| "marker_symbol": "Itgb6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96615", | |
| "marker_symbol": "Itgb6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Fear Conditioning"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0020421", | |
| "mp_term_name": "increased freezing behavior" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96647", | |
| "marker_symbol": "Junb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Organ Weight", "Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96673", | |
| "marker_symbol": "Kcne1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96673", | |
| "marker_symbol": "Kcne1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96816", | |
| "marker_symbol": "Lor", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96819", | |
| "marker_symbol": "Anxa1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96819", | |
| "marker_symbol": "Anxa1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004931", "mp_term_name": "enlarged epididymis" }, | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002631", | |
| "mp_term_name": "abnormal epididymis morphology" | |
| }, | |
| { "mp_term_id": "MP:0004906", "mp_term_name": "enlarged uterus" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96819", | |
| "marker_symbol": "Anxa1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96853", | |
| "marker_symbol": "Alad", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0010068", | |
| "mp_term_name": "decreased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96909", | |
| "marker_symbol": "Maf", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:96909", | |
| "marker_symbol": "Maf", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001614", | |
| "mp_term_name": "abnormal blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97008", | |
| "marker_symbol": "Mmp11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry", "Fasted Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97009", | |
| "marker_symbol": "Mmp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97009", | |
| "marker_symbol": "Mmp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97009", | |
| "marker_symbol": "Mmp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97009", | |
| "marker_symbol": "Mmp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97283", | |
| "marker_symbol": "Ncf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97283", | |
| "marker_symbol": "Ncf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001175", "mp_term_name": "abnormal lung morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97284", | |
| "marker_symbol": "Ncf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0012767", | |
| "mp_term_name": "increased KLRG1-positive NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004974", | |
| "mp_term_name": "decreased regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0005018", "mp_term_name": "decreased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0012765", | |
| "mp_term_name": "decreased alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008040", | |
| "mp_term_name": "decreased NK T cell number" | |
| }, | |
| { "mp_term_id": "MP:0008045", "mp_term_name": "decreased NK cell number" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97284", | |
| "marker_symbol": "Ncf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0012767", | |
| "mp_term_name": "increased KLRG1-positive NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004974", | |
| "mp_term_name": "decreased regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { "mp_term_id": "MP:0005018", "mp_term_name": "decreased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0012765", | |
| "mp_term_name": "decreased alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008040", | |
| "mp_term_name": "decreased NK T cell number" | |
| }, | |
| { "mp_term_id": "MP:0008045", "mp_term_name": "decreased NK cell number" } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97295", | |
| "marker_symbol": "Casp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001556", | |
| "mp_term_name": "increased circulating HDL cholesterol level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97295", | |
| "marker_symbol": "Casp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97303", | |
| "marker_symbol": "Nek1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0004509", | |
| "mp_term_name": "abnormal pelvic girdle bone morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97312", | |
| "marker_symbol": "Nfkb1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| }, | |
| { "mp_term_id": "MP:0001191", "mp_term_name": "abnormal skin condition" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97324", | |
| "marker_symbol": "Nhlh2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0006415", "mp_term_name": "absent testes" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0003642", "mp_term_name": "absent seminal vesicle" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { "mp_term_id": "MP:0003578", "mp_term_name": "absent ovary" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97359", | |
| "marker_symbol": "Nodal", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0012362", | |
| "mp_term_name": "increased large unstained cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97362", | |
| "marker_symbol": "Nos3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97372", | |
| "marker_symbol": "Npr2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002111", | |
| "mp_term_name": "abnormal tail morphology" | |
| }, | |
| { "mp_term_id": "MP:0011999", "mp_term_name": "abnormal tail length" }, | |
| { | |
| "mp_term_id": "MP:0000556", | |
| "mp_term_name": "abnormal hindlimb morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000550", | |
| "mp_term_name": "abnormal forelimb morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97388", | |
| "marker_symbol": "Nucb1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97473", | |
| "marker_symbol": "Pah", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97489", | |
| "marker_symbol": "Pax5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008806", | |
| "mp_term_name": "increased circulating amylase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011886", | |
| "mp_term_name": "increased circulating lipase level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97490", | |
| "marker_symbol": "Pax6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97512", | |
| "marker_symbol": "Pcsk2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000367", | |
| "mp_term_name": "abnormal coat/ hair morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97515", | |
| "marker_symbol": "Pcsk5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Plasma Chemistry", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97515", | |
| "marker_symbol": "Pcsk5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97525", | |
| "marker_symbol": "Pde6b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Food efficiency (GMC)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0012311", | |
| "mp_term_name": "decreased defecation amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97542", | |
| "marker_symbol": "Pepd", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "Heart Weight", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002932", | |
| "mp_term_name": "abnormal joint morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97548", | |
| "marker_symbol": "Pfkm", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97548", | |
| "marker_symbol": "Pfkm", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97569", | |
| "marker_symbol": "Abcb4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97613", | |
| "marker_symbol": "Plcb1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97613", | |
| "marker_symbol": "Plcb1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97749", | |
| "marker_symbol": "Ppia", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97749", | |
| "marker_symbol": "Ppia", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97749", | |
| "marker_symbol": "Ppia", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97749", | |
| "marker_symbol": "Ppia", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:97851", | |
| "marker_symbol": "Slc20a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98002", | |
| "marker_symbol": "Rpl12", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98002", | |
| "marker_symbol": "Rpl12", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98289", | |
| "marker_symbol": "Scg5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98362", | |
| "marker_symbol": "Sox14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98362", | |
| "marker_symbol": "Sox14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Lung mechanics by forced oscillations"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010935", | |
| "mp_term_name": "increased airway resistance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011047", | |
| "mp_term_name": "increased lung tissue damping" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98362", | |
| "marker_symbol": "Sox14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Fertility of Homozygous Knock-out Mice" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98362", | |
| "marker_symbol": "Sox14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98366", | |
| "marker_symbol": "Sox4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { "mp_term_id": "MP:0000774", "mp_term_name": "decreased brain size" }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98386", | |
| "marker_symbol": "Sptan1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98389", | |
| "marker_symbol": "Spp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0006203", "mp_term_name": "eye hemorrhage" }, | |
| { "mp_term_id": "MP:0005542", "mp_term_name": "corneal vascularization" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98389", | |
| "marker_symbol": "Spp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005287", "mp_term_name": "narrow eye opening" }, | |
| { "mp_term_id": "MP:0006203", "mp_term_name": "eye hemorrhage" }, | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0012121", "mp_term_name": "sclerocornea" }, | |
| { "mp_term_id": "MP:0005542", "mp_term_name": "corneal vascularization" }, | |
| { "mp_term_id": "MP:0005176", "mp_term_name": "eyelids fail to open" }, | |
| { | |
| "mp_term_id": "MP:0001340", | |
| "mp_term_name": "abnormal eyelid morphology" | |
| }, | |
| { "mp_term_id": "MP:0002750", "mp_term_name": "exophthalmos" }, | |
| { "mp_term_id": "MP:0005544", "mp_term_name": "corneal deposits" } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98487", | |
| "marker_symbol": "Tat", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98488", | |
| "marker_symbol": "Slc6a6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Light-Dark Test", "Eye Morphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0006243", | |
| "mp_term_name": "impaired pupillary reflex" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98488", | |
| "marker_symbol": "Slc6a6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98488", | |
| "marker_symbol": "Slc6a6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98512", | |
| "marker_symbol": "Ubtf", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98512", | |
| "marker_symbol": "Ubtf", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98790", | |
| "marker_symbol": "Top2a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98790", | |
| "marker_symbol": "Top2a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E14.5-E15.5 Secondary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013294", | |
| "mp_term_name": "prenatal lethality prior to heart atrial septation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98790", | |
| "marker_symbol": "Top2a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98821", | |
| "marker_symbol": "Trf", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001565", | |
| "mp_term_name": "abnormal circulating phosphate level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004151", | |
| "mp_term_name": "decreased circulating iron level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98823", | |
| "marker_symbol": "Trh", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000470", | |
| "mp_term_name": "abnormal stomach morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98872", | |
| "marker_symbol": "Twist1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98970", | |
| "marker_symbol": "Xbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Modified SHIRPA"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001756", "mp_term_name": "abnormal urination" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:98970", | |
| "marker_symbol": "Xbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99217", | |
| "marker_symbol": "Cdh11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99217", | |
| "marker_symbol": "Cdh11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99698", | |
| "marker_symbol": "Clock", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001556", | |
| "mp_term_name": "increased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99698", | |
| "marker_symbol": "Clock", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99782", | |
| "marker_symbol": "Nt5e", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99782", | |
| "marker_symbol": "Nt5e", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99782", | |
| "marker_symbol": "Nt5e", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99782", | |
| "marker_symbol": "Nt5e", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99960", | |
| "marker_symbol": "Ewsr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:99960", | |
| "marker_symbol": "Ewsr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength", "Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101766", | |
| "marker_symbol": "Ryk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:101769", | |
| "marker_symbol": "Mcl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102465", | |
| "marker_symbol": "Tex2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102465", | |
| "marker_symbol": "Tex2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102465", | |
| "marker_symbol": "Tex2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004222", "mp_term_name": "iris synechia" }, | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001307", "mp_term_name": "fused cornea and lens" }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102780", | |
| "marker_symbol": "Six1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" }, | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102780", | |
| "marker_symbol": "Six1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Placenta E14.5-E15.5", | |
| "Electrocardiogram (ECG)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001614", | |
| "mp_term_name": "abnormal blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" }, | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102780", | |
| "marker_symbol": "Six1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102805", | |
| "marker_symbol": "Entpd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002896", | |
| "mp_term_name": "abnormal bone mineralization" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:102853", | |
| "marker_symbol": "Elk4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Haematology test", "FACs Analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008079", | |
| "mp_term_name": "decreased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { "mp_term_id": "MP:0005014", "mp_term_name": "increased B cell number" }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008211", | |
| "mp_term_name": "decreased mature B cell number" | |
| }, | |
| { "mp_term_id": "MP:0005015", "mp_term_name": "increased T cell number" }, | |
| { "mp_term_id": "MP:0005018", "mp_term_name": "decreased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0008075", | |
| "mp_term_name": "decreased CD4-positive, alpha beta T cell number" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103013", | |
| "marker_symbol": "Cacna1c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000601", "mp_term_name": "small liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103013", | |
| "marker_symbol": "Cacna1c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103022", | |
| "marker_symbol": "Reln", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103063", | |
| "marker_symbol": "Stat1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { | |
| "mp_term_id": "MP:0012362", | |
| "mp_term_name": "increased large unstained cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103063", | |
| "marker_symbol": "Stat1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103201", | |
| "marker_symbol": "Aqp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103222", | |
| "marker_symbol": "Zbtb16", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000774", "mp_term_name": "decreased brain size" }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103222", | |
| "marker_symbol": "Zbtb16", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103222", | |
| "marker_symbol": "Zbtb16", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103226", | |
| "marker_symbol": "Cox7c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103226", | |
| "marker_symbol": "Cox7c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011239", | |
| "mp_term_name": "abnormal skin coloration" | |
| }, | |
| { "mp_term_id": "MP:0003717", "mp_term_name": "pallor" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103298", | |
| "marker_symbol": "Apobec1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103298", | |
| "marker_symbol": "Apobec1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103298", | |
| "marker_symbol": "Apobec1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:103298", | |
| "marker_symbol": "Apobec1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104294", | |
| "marker_symbol": "Tyro3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104327", | |
| "marker_symbol": "Nog", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002759", | |
| "mp_term_name": "abnormal caudal vertebrae morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104327", | |
| "marker_symbol": "Nog", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0002759", | |
| "mp_term_name": "abnormal caudal vertebrae morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104510", | |
| "marker_symbol": "Myo7a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Hot Plate", | |
| "Open-field", | |
| "Modified SHIRPA" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001973", | |
| "mp_term_name": "increased thermal nociceptive threshold" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003313", | |
| "mp_term_name": "abnormal locomotor activation" | |
| }, | |
| { "mp_term_id": "MP:0001512", "mp_term_name": "trunk curl" }, | |
| { | |
| "mp_term_id": "MP:0001523", | |
| "mp_term_name": "impaired righting response" | |
| }, | |
| { "mp_term_id": "MP:0001408", "mp_term_name": "stereotypic behavior" }, | |
| { "mp_term_id": "MP:0006358", "mp_term_name": "absent pinna reflex" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104602", | |
| "marker_symbol": "Prpf39", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005641", | |
| "mp_term_name": "increased mean corpuscular hemoglobin concentration" | |
| }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104606", | |
| "marker_symbol": "Rab34", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000562", "mp_term_name": "polydactyly" }, | |
| { | |
| "mp_term_id": "MP:0002109", | |
| "mp_term_name": "abnormal limb morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104606", | |
| "marker_symbol": "Rab34", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104630", | |
| "marker_symbol": "Wars", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008528", "mp_term_name": "polycystic kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104630", | |
| "marker_symbol": "Wars", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104630", | |
| "marker_symbol": "Wars", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104634", | |
| "marker_symbol": "Tle3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000774", "mp_term_name": "decreased brain size" }, | |
| { | |
| "mp_term_id": "MP:0002152", | |
| "mp_term_name": "abnormal brain morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104634", | |
| "marker_symbol": "Tle3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104634", | |
| "marker_symbol": "Tle3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104637", | |
| "marker_symbol": "Tgfbr3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104663", | |
| "marker_symbol": "Lep", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104669", | |
| "marker_symbol": "Man2a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000494", | |
| "mp_term_name": "abnormal cecum morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104723", | |
| "marker_symbol": "Fgf9", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104749", | |
| "marker_symbol": "Osm", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104785", | |
| "marker_symbol": "Myo6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000157", | |
| "mp_term_name": "abnormal sternum morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104898", | |
| "marker_symbol": "Gpcpd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104961", | |
| "marker_symbol": "Tnfaip1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-Ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104976", | |
| "marker_symbol": "Ddx6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104976", | |
| "marker_symbol": "Ddx6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:104993", | |
| "marker_symbol": "Lepr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105077", | |
| "marker_symbol": "Hsd17b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005627", | |
| "mp_term_name": "increased circulating potassium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003020", | |
| "mp_term_name": "decreased circulating chloride level" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105082", | |
| "marker_symbol": "Ssr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105082", | |
| "marker_symbol": "Ssr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105089", | |
| "marker_symbol": "Hsd17b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105089", | |
| "marker_symbol": "Hsd17b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105089", | |
| "marker_symbol": "Hsd17b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001319", | |
| "mp_term_name": "irregularly shaped pupil" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0001322", | |
| "mp_term_name": "abnormal iris morphology" | |
| }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105089", | |
| "marker_symbol": "Hsd17b4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105917", | |
| "marker_symbol": "Fer", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Gross Pathology and Tissue Collection", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105926", | |
| "marker_symbol": "Rab5a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:105926", | |
| "marker_symbol": "Rab5a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Grip Strength", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Sleep Wake" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001488", | |
| "mp_term_name": "increased startle reflex" | |
| }, | |
| { "mp_term_id": "MP:0011396", "mp_term_name": "abnormal sleep behavior" }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106091", | |
| "marker_symbol": "Cyp7a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001556", | |
| "mp_term_name": "increased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004151", | |
| "mp_term_name": "decreased circulating iron level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011896", | |
| "mp_term_name": "increased circulating unsaturated transferrin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005344", | |
| "mp_term_name": "increased circulating bilirubin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005566", | |
| "mp_term_name": "decreased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106091", | |
| "marker_symbol": "Cyp7a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106209", | |
| "marker_symbol": "Hells", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["FACs Analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008078", | |
| "mp_term_name": "increased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000223", | |
| "mp_term_name": "decreased monocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106209", | |
| "marker_symbol": "Hells", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106227", | |
| "marker_symbol": "Capza1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106604", | |
| "marker_symbol": "Gpld1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106626", | |
| "marker_symbol": "Dusp8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:106626", | |
| "marker_symbol": "Dusp8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107160", | |
| "marker_symbol": "Hmx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107191", | |
| "marker_symbol": "Bmpr1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107363", | |
| "marker_symbol": "Stxbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107363", | |
| "marker_symbol": "Stxbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107374", | |
| "marker_symbol": "Pitx1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107374", | |
| "marker_symbol": "Pitx1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107374", | |
| "marker_symbol": "Pitx1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000579", "mp_term_name": "abnormal nail morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107403", | |
| "marker_symbol": "Clk1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Haematology", "Immunoglobulin", "FACs Analysis"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0005505", "mp_term_name": "thrombocytosis" }, | |
| { | |
| "mp_term_id": "MP:0000334", | |
| "mp_term_name": "decreased granulocyte number" | |
| }, | |
| { "mp_term_id": "MP:0008501", "mp_term_name": "increased IgG2b level" }, | |
| { "mp_term_id": "MP:0008045", "mp_term_name": "decreased NK cell number" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107444", | |
| "marker_symbol": "Efna5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000642", "mp_term_name": "enlarged adrenal glands" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107464", | |
| "marker_symbol": "Plcb4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005084", | |
| "mp_term_name": "abnormal gallbladder morphology" | |
| }, | |
| { "mp_term_id": "MP:0009342", "mp_term_name": "enlarged gallbladder" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107476", | |
| "marker_symbol": "Stim1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002339", | |
| "mp_term_name": "abnormal lymph node morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107476", | |
| "marker_symbol": "Stim1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107484", | |
| "marker_symbol": "Rgl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": [ | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107484", | |
| "marker_symbol": "Rgl1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E9.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107489", | |
| "marker_symbol": "Phex", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Modified SHIRPA"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001391", "mp_term_name": "abnormal tail movements" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107489", | |
| "marker_symbol": "Phex", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["DEXA", "X-Ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000558", | |
| "mp_term_name": "abnormal tibia morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000137", | |
| "mp_term_name": "abnormal vertebrae morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000552", | |
| "mp_term_name": "abnormal radius morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004599", | |
| "mp_term_name": "abnormal vertebral arch morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002896", | |
| "mp_term_name": "abnormal bone mineralization" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002932", | |
| "mp_term_name": "abnormal joint morphology" | |
| }, | |
| { "mp_term_id": "MP:0005108", "mp_term_name": "abnormal ulna morphology" } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107567", | |
| "marker_symbol": "Irgm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010088", | |
| "mp_term_name": "decreased circulating fructosamine level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000182", | |
| "mp_term_name": "increased circulating LDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013278", | |
| "mp_term_name": "decreased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005292", | |
| "mp_term_name": "improved glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107577", | |
| "marker_symbol": "Wbp1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011960", | |
| "mp_term_name": "abnormal eye anterior chamber depth" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107577", | |
| "marker_symbol": "Wbp1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107690", | |
| "marker_symbol": "Zfp462", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107716", | |
| "marker_symbol": "Myo10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { | |
| "mp_term_id": "MP:0006243", | |
| "mp_term_name": "impaired pupillary reflex" | |
| }, | |
| { "mp_term_id": "MP:0001307", "mp_term_name": "fused cornea and lens" }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001322", | |
| "mp_term_name": "abnormal iris morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107755", | |
| "marker_symbol": "Neurod2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107755", | |
| "marker_symbol": "Neurod2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107788", | |
| "marker_symbol": "Atp1b3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003864", | |
| "mp_term_name": "abnormal midbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003232", | |
| "mp_term_name": "abnormal forebrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107792", | |
| "marker_symbol": "Lhx5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:107823", | |
| "marker_symbol": "Ctsk", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:108077", | |
| "marker_symbol": "Nptn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { "mp_term_id": "MP:0000745", "mp_term_name": "tremors" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0001406", "mp_term_name": "abnormal gait" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { "mp_term_id": "MP:0001513", "mp_term_name": "limb grasping" }, | |
| { "mp_term_id": "MP:0001486", "mp_term_name": "abnormal startle reflex" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 9 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:108426", | |
| "marker_symbol": "Kif1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002109", "mp_term_name": "abnormal limb morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:108519", | |
| "marker_symbol": "Meis3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109128", | |
| "marker_symbol": "Hnf4a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Age monitoring"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109151", | |
| "marker_symbol": "Ltbp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Dysmorphology", | |
| "Hot Plate", | |
| "Dexa-scan analysis", | |
| "Grip Strength", | |
| "X-ray", | |
| "Heart Dissection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" }, | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005358", | |
| "mp_term_name": "abnormal incisor morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109185", | |
| "marker_symbol": "Ccn3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109185", | |
| "marker_symbol": "Ccn3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109189", | |
| "marker_symbol": "Fgf14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Lung mechanics by forced oscillations"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109189", | |
| "marker_symbol": "Fgf14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109207", | |
| "marker_symbol": "Eif4g2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field - centre start"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109249", | |
| "marker_symbol": "Adamts1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Placenta E18.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109249", | |
| "marker_symbol": "Adamts1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109320", | |
| "marker_symbol": "Mmp15", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011239", "mp_term_name": "abnormal skin coloration" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109331", | |
| "marker_symbol": "Nxn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109331", | |
| "marker_symbol": "Nxn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109331", | |
| "marker_symbol": "Nxn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001556", | |
| "mp_term_name": "increased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109331", | |
| "marker_symbol": "Nxn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011495", "mp_term_name": "abnormal head shape" }, | |
| { "mp_term_id": "MP:0011496", "mp_term_name": "abnormal head size" }, | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| }, | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109331", | |
| "marker_symbol": "Nxn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002768", "mp_term_name": "small adrenal glands" }, | |
| { | |
| "mp_term_id": "MP:0000627", | |
| "mp_term_name": "abnormal mammary gland morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109331", | |
| "marker_symbol": "Nxn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Fear Conditioning", | |
| "Open-field", | |
| "Gross Morphology Embryo E18.5", | |
| "Open Field", | |
| "Grip-Strength" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001491", | |
| "mp_term_name": "unresponsive to tactile stimuli" | |
| }, | |
| { | |
| "mp_term_id": "MP:0020420", | |
| "mp_term_name": "abnormal freezing behavior" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001392", | |
| "mp_term_name": "abnormal locomotor behavior" | |
| }, | |
| { "mp_term_id": "MP:0001404", "mp_term_name": "no spontaneous movement" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109331", | |
| "marker_symbol": "Nxn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011960", | |
| "mp_term_name": "abnormal eye anterior chamber depth" | |
| }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001319", | |
| "mp_term_name": "irregularly shaped pupil" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001340", | |
| "mp_term_name": "abnormal eyelid morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109336", | |
| "marker_symbol": "Etv6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008821", | |
| "mp_term_name": "increased blood uric acid level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109336", | |
| "marker_symbol": "Etv6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0004857", "mp_term_name": "abnormal heart weight" }, | |
| { "mp_term_id": "MP:0000277", "mp_term_name": "abnormal heart shape" }, | |
| { "mp_term_id": "MP:0008725", "mp_term_name": "enlarged heart atrium" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109336", | |
| "marker_symbol": "Etv6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" }, | |
| { | |
| "mp_term_id": "MP:0012362", | |
| "mp_term_name": "increased large unstained cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109349", | |
| "marker_symbol": "Atf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Lung mechanics by forced oscillations" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109349", | |
| "marker_symbol": "Atf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Dark-Light Test"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109514", | |
| "marker_symbol": "Cstb", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109526", | |
| "marker_symbol": "Trpc3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002896", | |
| "mp_term_name": "abnormal bone mineralization" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1095404", | |
| "marker_symbol": "Mfng", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109563", | |
| "marker_symbol": "Cxcr4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109563", | |
| "marker_symbol": "Cxcr4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109587", | |
| "marker_symbol": "Tnfrsf11b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109587", | |
| "marker_symbol": "Tnfrsf11b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109617", | |
| "marker_symbol": "Barx2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| }, | |
| { "mp_term_id": "MP:0001284", "mp_term_name": "absent vibrissae" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109618", | |
| "marker_symbol": "Atp6v1b2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096347", | |
| "marker_symbol": "Sema3f", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008810", | |
| "mp_term_name": "increased circulating iron level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096347", | |
| "marker_symbol": "Sema3f", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096347", | |
| "marker_symbol": "Sema3f", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000579", "mp_term_name": "abnormal nail morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096362", | |
| "marker_symbol": "Nrxn2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005568", | |
| "mp_term_name": "increased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005565", | |
| "mp_term_name": "increased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:109637", | |
| "marker_symbol": "Erf", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096566", | |
| "marker_symbol": "Pias2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096875", | |
| "marker_symbol": "Wdfy3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1096875", | |
| "marker_symbol": "Wdfy3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001614", | |
| "mp_term_name": "abnormal blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1097156", | |
| "marker_symbol": "Ptgis", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098240", | |
| "marker_symbol": "Kif16b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098240", | |
| "marker_symbol": "Kif16b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098240", | |
| "marker_symbol": "Kif16b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098264", | |
| "marker_symbol": "Kif13a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098264", | |
| "marker_symbol": "Kif13a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098274", | |
| "marker_symbol": "Cyp27b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005016", | |
| "mp_term_name": "decreased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098687", | |
| "marker_symbol": "Aak1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Fear Conditioning", | |
| "Grip Strength", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001469", | |
| "mp_term_name": "abnormal contextual conditioning behavior" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002574", | |
| "mp_term_name": "increased vertical activity" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098687", | |
| "marker_symbol": "Aak1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "Heart Weight", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1098727", | |
| "marker_symbol": "Trappc1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1099804", | |
| "marker_symbol": "Hip1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { | |
| "mp_term_id": "MP:0001312", | |
| "mp_term_name": "abnormal cornea morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1099809", | |
| "marker_symbol": "Fgf10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100496", | |
| "marker_symbol": "Fmo3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100498", | |
| "marker_symbol": "Pitx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Food efficiency (GMC)", | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical chemistry (GMC)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005533", | |
| "mp_term_name": "increased body temperature" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002644", | |
| "mp_term_name": "decreased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100537", | |
| "marker_symbol": "Mid1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection", | |
| "Heart Weight", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100537", | |
| "marker_symbol": "Mid1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Fear Conditioning"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0020421", | |
| "mp_term_name": "increased freezing behavior" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100537", | |
| "marker_symbol": "Mid1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001289", | |
| "mp_term_name": "persistence of hyaloid vascular system" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100846", | |
| "marker_symbol": "Med1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1100846", | |
| "marker_symbol": "Med1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1101358", | |
| "marker_symbol": "Npepps", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0030610", "mp_term_name": "absent teeth" }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1194883", | |
| "marker_symbol": "Crx", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1194912", | |
| "marker_symbol": "Rbbp4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0001257", "mp_term_name": "increased body length" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1195262", | |
| "marker_symbol": "Man2b2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002768", "mp_term_name": "small adrenal glands" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1195458", | |
| "marker_symbol": "Abce1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1195458", | |
| "marker_symbol": "Abce1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1195458", | |
| "marker_symbol": "Abce1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1196256", | |
| "marker_symbol": "Kdm1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1196297", | |
| "marker_symbol": "Hgsnat", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000702", "mp_term_name": "enlarged lymph nodes" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1196297", | |
| "marker_symbol": "Hgsnat", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1196345", | |
| "marker_symbol": "Agpat5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| }, | |
| { "mp_term_id": "MP:0008045", "mp_term_name": "decreased NK cell number" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1197514", | |
| "marker_symbol": "Pole2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": [ | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0006108", | |
| "mp_term_name": "abnormal hindbrain development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009141", | |
| "mp_term_name": "increased prepulse inhibition" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1197514", | |
| "marker_symbol": "Pole2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1197514", | |
| "marker_symbol": "Pole2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { "mp_term_id": "MP:0003642", "mp_term_name": "absent seminal vesicle" }, | |
| { | |
| "mp_term_id": "MP:0002997", | |
| "mp_term_name": "enlarged seminal vesicle" | |
| }, | |
| { "mp_term_id": "MP:0009084", "mp_term_name": "blind uterus" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1197514", | |
| "marker_symbol": "Pole2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1197514", | |
| "marker_symbol": "Pole2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1201679", | |
| "marker_symbol": "Cxadr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1201679", | |
| "marker_symbol": "Cxadr", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000470", | |
| "mp_term_name": "abnormal stomach morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1201778", | |
| "marker_symbol": "Atp6v0d1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1202715", | |
| "marker_symbol": "Tcf21", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1203732", | |
| "marker_symbol": "Slc16a2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Dissection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1261819", | |
| "marker_symbol": "Dnmt3b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001297", "mp_term_name": "microphthalmia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1261820", | |
| "marker_symbol": "Cand1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1261820", | |
| "marker_symbol": "Cand1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1261910", | |
| "marker_symbol": "Pibf1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Sleep Wake"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0011396", "mp_term_name": "abnormal sleep behavior" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1270862", | |
| "marker_symbol": "Axin2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001672", | |
| "mp_term_name": "abnormal embryo development" | |
| }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1270862", | |
| "marker_symbol": "Axin2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0009908", "mp_term_name": "protruding tongue" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277096", | |
| "marker_symbol": "Ptp4a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277212", | |
| "marker_symbol": "Zfp644", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277957", | |
| "marker_symbol": "Kcnn4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277958", | |
| "marker_symbol": "Pcm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277958", | |
| "marker_symbol": "Pcm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277958", | |
| "marker_symbol": "Pcm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001488", "mp_term_name": "increased startle reflex" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1277959", | |
| "marker_symbol": "Dlg4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "Dexa-scan analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1278321", | |
| "marker_symbol": "Epc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0001186", | |
| "top_level_mp_term_name": "pigmentation phenotype" | |
| }, | |
| "procedures": ["Indirect ophthalmoscopy"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005103", | |
| "mp_term_name": "abnormal retina pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1278321", | |
| "marker_symbol": "Epc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002797", "mp_term_name": "increased thigmotaxis" }, | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289184", | |
| "marker_symbol": "Setd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289298", | |
| "marker_symbol": "Knstrn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1289298", | |
| "marker_symbol": "Knstrn", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005561", | |
| "mp_term_name": "increased mean corpuscular hemoglobin" | |
| }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1298378", | |
| "marker_symbol": "Dhcr7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1298378", | |
| "marker_symbol": "Dhcr7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003231", | |
| "mp_term_name": "abnormal placenta vasculature" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1298392", | |
| "marker_symbol": "Bscl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Indirect Calorimetry", | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005568", | |
| "mp_term_name": "increased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002965", | |
| "mp_term_name": "increased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001556", | |
| "mp_term_name": "increased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005559", | |
| "mp_term_name": "increased circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005292", | |
| "mp_term_name": "improved glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001566", | |
| "mp_term_name": "increased circulating phosphate level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000194", | |
| "mp_term_name": "increased circulating calcium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010379", | |
| "mp_term_name": "decreased respiratory quotient" | |
| } | |
| ], | |
| "phenotype_count": 13 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1314882", | |
| "marker_symbol": "Hipk3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009142", | |
| "mp_term_name": "decreased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1314884", | |
| "marker_symbol": "Tnfrsf1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1314884", | |
| "marker_symbol": "Tnfrsf1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Immunophenotyping", "Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002606", | |
| "mp_term_name": "increased basophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008044", | |
| "mp_term_name": "increased NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010850", | |
| "mp_term_name": "increased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000222", | |
| "mp_term_name": "decreased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012362", | |
| "mp_term_name": "increased large unstained cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005013", | |
| "mp_term_name": "increased lymphocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000223", | |
| "mp_term_name": "decreased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 10 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1316658", | |
| "marker_symbol": "Cyba", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1321396", | |
| "marker_symbol": "Pstpip1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000162", "mp_term_name": "lordosis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1328360", | |
| "marker_symbol": "Arid3a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1328360", | |
| "marker_symbol": "Arid3a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Placenta E14.5-E15.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001711", | |
| "mp_term_name": "abnormal placenta morphology" | |
| }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1328360", | |
| "marker_symbol": "Arid3a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001914", "mp_term_name": "hemorrhage" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1329038", | |
| "marker_symbol": "Mllt10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1329038", | |
| "marker_symbol": "Mllt10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1329045", | |
| "marker_symbol": "Tulp3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013278", | |
| "mp_term_name": "decreased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005344", | |
| "mp_term_name": "increased circulating bilirubin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1330293", | |
| "marker_symbol": "Krtap8-1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Lung mechanics by forced oscillations" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1330302", | |
| "marker_symbol": "Dyrk1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009141", | |
| "mp_term_name": "increased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1330302", | |
| "marker_symbol": "Dyrk1b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1330806", | |
| "marker_symbol": "Arg2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333753", | |
| "marker_symbol": "Pdcd6ip", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0008528", "mp_term_name": "polycystic kidney" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333753", | |
| "marker_symbol": "Pdcd6ip", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333786", | |
| "marker_symbol": "Car6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0013129", "mp_term_name": "abnormal tooth color" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1333853", | |
| "marker_symbol": "Hs3st3b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1335088", | |
| "marker_symbol": "Pstpip2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000137", | |
| "mp_term_name": "abnormal vertebrae morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1336167", | |
| "marker_symbol": "Prkab1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Gross Morphology Embryo E18.5", | |
| "Grip Strength", | |
| "Modified SHIRPA" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001413", | |
| "mp_term_name": "abnormal response to new environment" | |
| }, | |
| { "mp_term_id": "MP:0001404", "mp_term_name": "no spontaneous movement" }, | |
| { "mp_term_id": "MP:0006358", "mp_term_name": "absent pinna reflex" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1336167", | |
| "marker_symbol": "Prkab1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Gross Pathology and Tissue Collection", | |
| "Ophthalmoscope" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010098", | |
| "mp_term_name": "abnormal retina blood vessel pattern" | |
| }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0011965", | |
| "mp_term_name": "decreased total retina thickness" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003733", | |
| "mp_term_name": "abnormal retina inner nuclear layer morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1336880", | |
| "marker_symbol": "Eftud2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001488", | |
| "mp_term_name": "increased startle reflex" | |
| }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1336993", | |
| "marker_symbol": "Ap4e1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Dexa-scan analysis", | |
| "X-ray" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000137", | |
| "mp_term_name": "abnormal vertebrae morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004599", | |
| "mp_term_name": "abnormal vertebral arch morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010123", | |
| "mp_term_name": "increased bone mineral content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000062", | |
| "mp_term_name": "increased bone mineral density" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338755", | |
| "marker_symbol": "Rnd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338850", | |
| "marker_symbol": "Mthfd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000428", | |
| "mp_term_name": "abnormal craniofacial morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338850", | |
| "marker_symbol": "Mthfd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338850", | |
| "marker_symbol": "Mthfd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E14.5-E15.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013294", | |
| "mp_term_name": "prenatal lethality prior to heart atrial septation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338881", | |
| "marker_symbol": "St14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004848", "mp_term_name": "abnormal liver size" }, | |
| { "mp_term_id": "MP:0000603", "mp_term_name": "pale liver" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1338898", | |
| "marker_symbol": "Padi4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1339711", | |
| "marker_symbol": "Myh1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000221", | |
| "mp_term_name": "decreased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1339999", | |
| "marker_symbol": "Krt27", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1341087", | |
| "marker_symbol": "Tnks", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011965", | |
| "mp_term_name": "decreased total retina thickness" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1341724", | |
| "marker_symbol": "Ggps1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1343087", | |
| "marker_symbol": "Pdk2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1344361", | |
| "marker_symbol": "Arih2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1344408", | |
| "marker_symbol": "Pebp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005084", | |
| "mp_term_name": "abnormal gallbladder morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345282", | |
| "marker_symbol": "Slc30a4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002768", "mp_term_name": "small adrenal glands" }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { "mp_term_id": "MP:0000706", "mp_term_name": "small thymus" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345282", | |
| "marker_symbol": "Slc30a4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { "mp_term_id": "MP:0000745", "mp_term_name": "tremors" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345283", | |
| "marker_symbol": "Slc25a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001672", | |
| "mp_term_name": "abnormal embryo development" | |
| }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345283", | |
| "marker_symbol": "Slc25a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003717", "mp_term_name": "pallor" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1345643", | |
| "marker_symbol": "Sufu", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Placenta E12.5", | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004258", "mp_term_name": "abnormal placenta size" }, | |
| { "mp_term_id": "MP:0001722", "mp_term_name": "pale yolk sac" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1347348", | |
| "marker_symbol": "Adamts6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1347348", | |
| "marker_symbol": "Adamts6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1347522", | |
| "marker_symbol": "Pla2g10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart weight/tibia length", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004156", "mp_term_name": "abnormal QT variability" }, | |
| { "mp_term_id": "MP:0010506", "mp_term_name": "prolonged RR interval" }, | |
| { "mp_term_id": "MP:0003233", "mp_term_name": "prolonged QT interval" }, | |
| { | |
| "mp_term_id": "MP:0003928", | |
| "mp_term_name": "increased heart rate variability" | |
| }, | |
| { "mp_term_id": "MP:0005333", "mp_term_name": "decreased heart rate" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1347522", | |
| "marker_symbol": "Pla2g10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["FACs Analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008211", | |
| "mp_term_name": "decreased mature B cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1347522", | |
| "marker_symbol": "Pla2g10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["FACs Analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008211", | |
| "mp_term_name": "decreased mature B cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1349475", | |
| "marker_symbol": "Ppp2r5c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1349475", | |
| "marker_symbol": "Ppp2r5c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1350360", | |
| "marker_symbol": "Tspan32", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351315", | |
| "marker_symbol": "Eloa", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351315", | |
| "marker_symbol": "Eloa", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351619", | |
| "marker_symbol": "Abcb11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351619", | |
| "marker_symbol": "Abcb11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001402", | |
| "mp_term_name": "decreased locomotor activity" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351629", | |
| "marker_symbol": "Pign", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351629", | |
| "marker_symbol": "Pign", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1351629", | |
| "marker_symbol": "Pign", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352447", | |
| "marker_symbol": "Abcc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001556", | |
| "mp_term_name": "increased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005344", | |
| "mp_term_name": "increased circulating bilirubin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005343", | |
| "mp_term_name": "increased circulating aspartate transaminase level" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352459", | |
| "marker_symbol": "Nr6a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002861", | |
| "mp_term_name": "abnormal tail bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352459", | |
| "marker_symbol": "Nr6a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002884", | |
| "mp_term_name": "abnormal pharyngeal arch morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352459", | |
| "marker_symbol": "Nr6a1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000269", "mp_term_name": "abnormal heart looping" }, | |
| { | |
| "mp_term_id": "MP:0000288", | |
| "mp_term_name": "abnormal pericardium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352760", | |
| "marker_symbol": "Hdgfl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001415", | |
| "mp_term_name": "increased exploration in new environment" | |
| }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1352760", | |
| "marker_symbol": "Hdgfl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353466", | |
| "marker_symbol": "Mmp20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Acoustic Startle and Pre-pulse Inhibition (PPI)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009141", | |
| "mp_term_name": "increased prepulse inhibition" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353466", | |
| "marker_symbol": "Mmp20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0013129", "mp_term_name": "abnormal tooth color" }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353510", | |
| "marker_symbol": "Arhgef1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353569", | |
| "marker_symbol": "Foxe3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field", "Hole-board Exploration"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001415", | |
| "mp_term_name": "increased exploration in new environment" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002574", | |
| "mp_term_name": "increased vertical activity" | |
| }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353569", | |
| "marker_symbol": "Foxe3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1353644", | |
| "marker_symbol": "Zfp503", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354170", | |
| "marker_symbol": "Cbarp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354702", | |
| "marker_symbol": "Fbxl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005369", | |
| "top_level_mp_term_name": "muscle phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000759", | |
| "mp_term_name": "abnormal skeletal muscle morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354702", | |
| "marker_symbol": "Fbxl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0004953", "mp_term_name": "decreased spleen weight" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354724", | |
| "marker_symbol": "Sacs", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1354951", | |
| "marker_symbol": "Gne", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1355311", | |
| "marker_symbol": "Stag3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1355330", | |
| "marker_symbol": "Phgdh", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001672", | |
| "mp_term_name": "abnormal embryo development" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003229", | |
| "mp_term_name": "abnormal vitelline vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001718", | |
| "mp_term_name": "abnormal visceral yolk sac morphology" | |
| }, | |
| { "mp_term_id": "MP:0001700", "mp_term_name": "abnormal embryo turning" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1855699", | |
| "marker_symbol": "Vti1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004931", "mp_term_name": "enlarged epididymis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002631", | |
| "mp_term_name": "abnormal epididymis morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858213", | |
| "marker_symbol": "Clpp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858213", | |
| "marker_symbol": "Clpp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858277", | |
| "marker_symbol": "Gal3st1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1858277", | |
| "marker_symbol": "Gal3st1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0004599", | |
| "mp_term_name": "abnormal vertebral arch morphology" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859162", | |
| "marker_symbol": "Rnf10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859170", | |
| "marker_symbol": "Pdcd7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859631", | |
| "marker_symbol": "Pdgfc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004357", "mp_term_name": "long tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859665", | |
| "marker_symbol": "Atp8b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013278", | |
| "mp_term_name": "decreased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005292", | |
| "mp_term_name": "improved glucose tolerance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859665", | |
| "marker_symbol": "Atp8b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Grip Strength", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { "mp_term_id": "MP:0010053", "mp_term_name": "decreased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { "mp_term_id": "MP:0001486", "mp_term_name": "abnormal startle reflex" }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859665", | |
| "marker_symbol": "Atp8b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859665", | |
| "marker_symbol": "Atp8b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001157", "mp_term_name": "small seminal vesicle" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859665", | |
| "marker_symbol": "Atp8b1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001314", "mp_term_name": "corneal opacity" }, | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859866", | |
| "marker_symbol": "Cdc20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Plasma Chemistry", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005292", | |
| "mp_term_name": "improved glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005559", | |
| "mp_term_name": "increased circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859866", | |
| "marker_symbol": "Cdc20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1859866", | |
| "marker_symbol": "Cdc20", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004122", | |
| "mp_term_name": "abnormal sinus arrhythmia" | |
| }, | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860188", | |
| "marker_symbol": "Snx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E14.5-E15.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002111", | |
| "mp_term_name": "abnormal tail morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002109", | |
| "mp_term_name": "abnormal limb morphology" | |
| }, | |
| { "mp_term_id": "MP:0000564", "mp_term_name": "syndactyly" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860188", | |
| "marker_symbol": "Snx3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" }, | |
| { | |
| "mp_term_id": "MP:0005565", | |
| "mp_term_name": "increased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860765", | |
| "marker_symbol": "Extl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860765", | |
| "marker_symbol": "Extl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001158", | |
| "mp_term_name": "abnormal prostate gland morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1860765", | |
| "marker_symbol": "Extl3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1861354", | |
| "marker_symbol": "Apbb1ip", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Lung mechanics by forced oscillations"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010935", | |
| "mp_term_name": "increased airway resistance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1861731", | |
| "marker_symbol": "Ccl28", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1862037", | |
| "marker_symbol": "Slc12a5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000692", "mp_term_name": "small spleen" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1888520", | |
| "marker_symbol": "Brd4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1888921", | |
| "marker_symbol": "P3h1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1889001", | |
| "marker_symbol": "Nub1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1889341", | |
| "marker_symbol": "Hacd3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1889506", | |
| "marker_symbol": "Crlf2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890081", | |
| "marker_symbol": "Foxo3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0012121", "mp_term_name": "sclerocornea" }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890165", | |
| "marker_symbol": "Larp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890165", | |
| "marker_symbol": "Larp1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890219", | |
| "marker_symbol": "Cdh23", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890520", | |
| "marker_symbol": "Vps4a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0009908", "mp_term_name": "protruding tongue" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890541", | |
| "marker_symbol": "Pramel1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1890659", | |
| "marker_symbol": "Trim39", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002098", | |
| "mp_term_name": "abnormal vibrissa morphology" | |
| }, | |
| { "mp_term_id": "MP:0001284", "mp_term_name": "absent vibrissae" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891112", | |
| "marker_symbol": "Gmds", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010093", | |
| "mp_term_name": "decreased circulating magnesium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008810", | |
| "mp_term_name": "increased circulating iron level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891123", | |
| "marker_symbol": "Kcne2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Haematology test"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002591", | |
| "mp_term_name": "decreased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { "mp_term_id": "MP:0005505", "mp_term_name": "thrombocytosis" }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891160", | |
| "marker_symbol": "Chst2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891160", | |
| "marker_symbol": "Chst2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891295", | |
| "marker_symbol": "Ube3b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5", "Body Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001262", "mp_term_name": "decreased body weight" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891341", | |
| "marker_symbol": "Lpin2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891690", | |
| "marker_symbol": "Syncrip", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Grip Strength", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001488", | |
| "mp_term_name": "increased startle reflex" | |
| }, | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" }, | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891704", | |
| "marker_symbol": "Hbs1l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891827", | |
| "marker_symbol": "Gde1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005178", | |
| "mp_term_name": "increased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891827", | |
| "marker_symbol": "Gde1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)", | |
| "Open Field" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002757", | |
| "mp_term_name": "decreased vertical activity" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001489", | |
| "mp_term_name": "decreased startle reflex" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002574", | |
| "mp_term_name": "increased vertical activity" | |
| }, | |
| { "mp_term_id": "MP:0001406", "mp_term_name": "abnormal gait" }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1891917", | |
| "marker_symbol": "Ywhab", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913304", | |
| "marker_symbol": "Cndp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913304", | |
| "marker_symbol": "Cndp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001293", "mp_term_name": "anophthalmia" }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913310", | |
| "marker_symbol": "Cystm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913310", | |
| "marker_symbol": "Cystm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Indirect Calorimetry", "Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002757", | |
| "mp_term_name": "decreased vertical activity" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001364", | |
| "mp_term_name": "decreased anxiety-related response" | |
| }, | |
| { "mp_term_id": "MP:0020870", "mp_term_name": "decreased thigmotaxis" }, | |
| { "mp_term_id": "MP:0011940", "mp_term_name": "decreased food intake" }, | |
| { "mp_term_id": "MP:0001399", "mp_term_name": "hyperactivity" }, | |
| { | |
| "mp_term_id": "MP:0001417", | |
| "mp_term_name": "decreased exploration in new environment" | |
| }, | |
| { "mp_term_id": "MP:0004924", "mp_term_name": "abnormal behavior" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913333", | |
| "marker_symbol": "Setd6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913333", | |
| "marker_symbol": "Setd6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0012121", "mp_term_name": "sclerocornea" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913346", | |
| "marker_symbol": "Lamtor4", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E12.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013293", | |
| "mp_term_name": "embryonic lethality prior to tooth bud stage" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913533", | |
| "marker_symbol": "Gkn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000458", | |
| "mp_term_name": "abnormal mandible morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913533", | |
| "marker_symbol": "Gkn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913533", | |
| "marker_symbol": "Gkn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Fertility of Homozygous Knock-out Mice" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001120", | |
| "mp_term_name": "abnormal uterus morphology" | |
| }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" }, | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913653", | |
| "marker_symbol": "Asf1a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002151", | |
| "mp_term_name": "abnormal neural tube morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913693", | |
| "marker_symbol": "Tnfaip8l1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000601", "mp_term_name": "small liver" }, | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { | |
| "mp_term_id": "MP:0000598", | |
| "mp_term_name": "abnormal liver morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913693", | |
| "marker_symbol": "Tnfaip8l1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001486", "mp_term_name": "abnormal startle reflex" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913758", | |
| "marker_symbol": "Lamtor1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001102", | |
| "mp_term_name": "small superior vagus ganglion" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913758", | |
| "marker_symbol": "Lamtor1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913758", | |
| "marker_symbol": "Lamtor1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004931", "mp_term_name": "enlarged epididymis" }, | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002631", | |
| "mp_term_name": "abnormal epididymis morphology" | |
| }, | |
| { "mp_term_id": "MP:0001148", "mp_term_name": "enlarged testis" }, | |
| { "mp_term_id": "MP:0009709", "mp_term_name": "hydrometra" } | |
| ], | |
| "phenotype_count": 7 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913775", | |
| "marker_symbol": "Timm50", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913789", | |
| "marker_symbol": "Xpo5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913865", | |
| "marker_symbol": "Atg4b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002941", | |
| "mp_term_name": "increased circulating alanine transaminase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000186", | |
| "mp_term_name": "decreased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005566", | |
| "mp_term_name": "decreased blood urea nitrogen level" | |
| } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913865", | |
| "marker_symbol": "Atg4b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913865", | |
| "marker_symbol": "Atg4b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology", "X-ray"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913865", | |
| "marker_symbol": "Atg4b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913879", | |
| "marker_symbol": "Golph3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001552", | |
| "mp_term_name": "increased circulating triglyceride level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913896", | |
| "marker_symbol": "Rpe", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913906", | |
| "marker_symbol": "Eef1d", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913906", | |
| "marker_symbol": "Eef1d", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000219", | |
| "mp_term_name": "increased neutrophil cell number" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913906", | |
| "marker_symbol": "Eef1d", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913941", | |
| "marker_symbol": "Gapvd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001415", | |
| "mp_term_name": "increased exploration in new environment" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913941", | |
| "marker_symbol": "Gapvd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": [ | |
| "Viability Primary Screen", | |
| "Viability E14.5-E15.5 Secondary Screen", | |
| "Viability E9.5 Secondary Screen" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013294", | |
| "mp_term_name": "prenatal lethality prior to heart atrial septation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013292", | |
| "mp_term_name": "embryonic lethality prior to organogenesis" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913941", | |
| "marker_symbol": "Gapvd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913955", | |
| "marker_symbol": "Dnase1l2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Dysmorphology", | |
| "Heart Weight", | |
| "X-ray" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000572", | |
| "mp_term_name": "abnormal autopod morphology" | |
| }, | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0002111", | |
| "mp_term_name": "abnormal tail morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000558", | |
| "mp_term_name": "abnormal tibia morphology" | |
| }, | |
| { "mp_term_id": "MP:0011999", "mp_term_name": "abnormal tail length" }, | |
| { | |
| "mp_term_id": "MP:0000556", | |
| "mp_term_name": "abnormal hindlimb morphology" | |
| }, | |
| { "mp_term_id": "MP:0002544", "mp_term_name": "brachydactyly" }, | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 8 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913955", | |
| "marker_symbol": "Dnase1l2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": [ | |
| "Body Composition (DEXA lean/fat)", | |
| "Dexa-scan analysis", | |
| "Heart Weight", | |
| "X-ray" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004613", | |
| "mp_term_name": "fusion of vertebral arches" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000558", | |
| "mp_term_name": "abnormal tibia morphology" | |
| }, | |
| { "mp_term_id": "MP:0002764", "mp_term_name": "short tibia" }, | |
| { | |
| "mp_term_id": "MP:0000137", | |
| "mp_term_name": "abnormal vertebrae morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000455", | |
| "mp_term_name": "abnormal maxilla morphology" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004174", | |
| "mp_term_name": "abnormal spine curvature" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002932", | |
| "mp_term_name": "abnormal joint morphology" | |
| }, | |
| { "mp_term_id": "MP:0004609", "mp_term_name": "vertebral fusion" } | |
| ], | |
| "phenotype_count": 12 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1913955", | |
| "marker_symbol": "Dnase1l2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Haematology test", | |
| "Hematology" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005641", | |
| "mp_term_name": "increased mean corpuscular hemoglobin concentration" | |
| }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914060", | |
| "marker_symbol": "Rbm22", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914061", | |
| "marker_symbol": "Duoxa2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001340", | |
| "mp_term_name": "abnormal eyelid morphology" | |
| }, | |
| { "mp_term_id": "MP:0001322", "mp_term_name": "abnormal iris morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914072", | |
| "marker_symbol": "Fbxo25", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914072", | |
| "marker_symbol": "Fbxo25", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914118", | |
| "marker_symbol": "Mfsd1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914162", | |
| "marker_symbol": "Bzw2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Heart Weight", "Electrocardiogram (ECG)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002833", "mp_term_name": "increased heart weight" }, | |
| { "mp_term_id": "MP:0002626", "mp_term_name": "increased heart rate" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914162", | |
| "marker_symbol": "Bzw2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914182", | |
| "marker_symbol": "Rexo1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E18.5" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002111", | |
| "mp_term_name": "abnormal tail morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914182", | |
| "marker_symbol": "Rexo1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005380", | |
| "top_level_mp_term_name": "embryo phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Morphology Embryo E12.5", | |
| "Gross Morphology Embryo E18.5", | |
| "Gross Morphology Embryo E9.5" | |
| ], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003984", | |
| "mp_term_name": "embryonic growth retardation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914228", | |
| "marker_symbol": "Luc7l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" }, | |
| { "mp_term_id": "MP:0003068", "mp_term_name": "enlarged kidney" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914228", | |
| "marker_symbol": "Luc7l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0002188", "mp_term_name": "small heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914228", | |
| "marker_symbol": "Luc7l", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": [ | |
| "Combined SHIRPA and Dysmorphology", | |
| "Gross Pathology and Tissue Collection" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| }, | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914244", | |
| "marker_symbol": "Cep19", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914256", | |
| "marker_symbol": "Cisd2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["DEXA"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0003960", | |
| "mp_term_name": "increased lean body mass" | |
| }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914346", | |
| "marker_symbol": "Mmachc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914383", | |
| "marker_symbol": "Gp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914457", | |
| "marker_symbol": "Lsm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005633", | |
| "mp_term_name": "increased circulating sodium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914457", | |
| "marker_symbol": "Lsm1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" }, | |
| { "mp_term_id": "MP:0001303", "mp_term_name": "abnormal lens morphology" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914649", | |
| "marker_symbol": "Pdlim7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914720", | |
| "marker_symbol": "Abcg8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Lung mechanics by forced oscillations"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010896", | |
| "mp_term_name": "decreased lung compliance" | |
| }, | |
| { "mp_term_id": "MP:0011044", "mp_term_name": "increased lung elastance" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914779", | |
| "marker_symbol": "Fgfr1op2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001785", "mp_term_name": "edema" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914792", | |
| "marker_symbol": "Cog6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Anti-nuclear antibody assay", | |
| "Hematology", | |
| "Spleen Immunophenotyping", | |
| "Mesenteric Lymph Node Immunophenotyping", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008045", | |
| "mp_term_name": "decreased NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013022", | |
| "mp_term_name": "increased Ly6C high monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008182", | |
| "mp_term_name": "decreased marginal zone B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008206", | |
| "mp_term_name": "increased B-2 B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013675", | |
| "mp_term_name": "decreased Ly6C-positive mature NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013418", | |
| "mp_term_name": "increased memory-marker gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013427", | |
| "mp_term_name": "increased memory-marker NK cell number" | |
| }, | |
| { "mp_term_id": "MP:0005018", "mp_term_name": "decreased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0012765", | |
| "mp_term_name": "decreased alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013421", | |
| "mp_term_name": "increased CD5-positive gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013519", | |
| "mp_term_name": "decreased CD4-positive NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008097", | |
| "mp_term_name": "increased plasma cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008079", | |
| "mp_term_name": "decreased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013522", | |
| "mp_term_name": "decreased memory-marker CD4-positive NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013426", | |
| "mp_term_name": "decreased memory-marker NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010851", | |
| "mp_term_name": "decreased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013764", | |
| "mp_term_name": "decreased T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010835", | |
| "mp_term_name": "increased CD4-positive, alpha-beta memory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013669", | |
| "mp_term_name": "decreased Ly6C-positive immature NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013511", | |
| "mp_term_name": "increased CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012767", | |
| "mp_term_name": "increased KLRG1-positive NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009926", | |
| "mp_term_name": "decreased transitional stage T2 B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008346", | |
| "mp_term_name": "increased gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013775", | |
| "mp_term_name": "increased KLRG1-positive T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008173", | |
| "mp_term_name": "increased follicular B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013157", | |
| "mp_term_name": "increased KLRG1+ CD4 alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013430", | |
| "mp_term_name": "increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013417", | |
| "mp_term_name": "decreased memory-marker gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000322", | |
| "mp_term_name": "increased granulocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010168", | |
| "mp_term_name": "increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013513", | |
| "mp_term_name": "decreased memory-marker CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013154", | |
| "mp_term_name": "increased KLRG1+ CD8 alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013433", | |
| "mp_term_name": "increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013772", | |
| "mp_term_name": "increased effector memory T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0004794", | |
| "mp_term_name": "increased anti-nuclear antigen antibody level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008040", | |
| "mp_term_name": "decreased NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013435", | |
| "mp_term_name": "decreased CD8-positive, naive alpha-beta T cell number" | |
| } | |
| ], | |
| "phenotype_count": 41 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1914792", | |
| "marker_symbol": "Cog6", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Spleen Immunophenotyping", | |
| "Mesenteric Lymph Node Immunophenotyping", | |
| "Whole blood peripheral blood leukocyte immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0008045", | |
| "mp_term_name": "decreased NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008182", | |
| "mp_term_name": "decreased marginal zone B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008206", | |
| "mp_term_name": "increased B-2 B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013675", | |
| "mp_term_name": "decreased Ly6C-positive mature NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013418", | |
| "mp_term_name": "increased memory-marker gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013427", | |
| "mp_term_name": "increased memory-marker NK cell number" | |
| }, | |
| { "mp_term_id": "MP:0005018", "mp_term_name": "decreased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0012765", | |
| "mp_term_name": "decreased alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013421", | |
| "mp_term_name": "increased CD5-positive gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013519", | |
| "mp_term_name": "decreased CD4-positive NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008097", | |
| "mp_term_name": "increased plasma cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008079", | |
| "mp_term_name": "decreased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013522", | |
| "mp_term_name": "decreased memory-marker CD4-positive NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013426", | |
| "mp_term_name": "decreased memory-marker NK cell number" | |
| }, | |
| { "mp_term_id": "MP:0000208", "mp_term_name": "decreased hematocrit" }, | |
| { | |
| "mp_term_id": "MP:0002875", | |
| "mp_term_name": "decreased erythrocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000218", | |
| "mp_term_name": "increased leukocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010851", | |
| "mp_term_name": "decreased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013764", | |
| "mp_term_name": "decreased T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013511", | |
| "mp_term_name": "increased CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010835", | |
| "mp_term_name": "increased CD4-positive, alpha-beta memory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013669", | |
| "mp_term_name": "decreased Ly6C-positive immature NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012767", | |
| "mp_term_name": "increased KLRG1-positive NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0009926", | |
| "mp_term_name": "decreased transitional stage T2 B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008346", | |
| "mp_term_name": "increased gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013775", | |
| "mp_term_name": "increased KLRG1-positive T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008173", | |
| "mp_term_name": "increased follicular B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002599", | |
| "mp_term_name": "increased mean platelet volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013157", | |
| "mp_term_name": "increased KLRG1+ CD4 alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002874", | |
| "mp_term_name": "decreased hemoglobin content" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013417", | |
| "mp_term_name": "decreased memory-marker gamma-delta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013430", | |
| "mp_term_name": "increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000322", | |
| "mp_term_name": "increased granulocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005562", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010168", | |
| "mp_term_name": "increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013513", | |
| "mp_term_name": "decreased memory-marker CD4-negative NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013154", | |
| "mp_term_name": "increased KLRG1+ CD8 alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013433", | |
| "mp_term_name": "increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013772", | |
| "mp_term_name": "increased effector memory T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013022", | |
| "mp_term_name": "increased Ly6C high monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008040", | |
| "mp_term_name": "decreased NK T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013435", | |
| "mp_term_name": "decreased CD8-positive, naive alpha-beta T cell number" | |
| } | |
| ], | |
| "phenotype_count": 47 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915023", | |
| "marker_symbol": "Kat8", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0009084", "mp_term_name": "blind uterus" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915040", | |
| "marker_symbol": "Rab39b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005377", | |
| "top_level_mp_term_name": "hearing/vestibular/ear phenotype" | |
| }, | |
| "procedures": ["Auditory Brain Stem Response"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0004738", | |
| "mp_term_name": "abnormal auditory brainstem response" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915040", | |
| "marker_symbol": "Rab39b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004953", "mp_term_name": "decreased spleen weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915171", | |
| "marker_symbol": "Ube2f", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E9.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005650", | |
| "mp_term_name": "abnormal limb bud morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915171", | |
| "marker_symbol": "Ube2f", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915248", | |
| "marker_symbol": "Retreg3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0001186", | |
| "top_level_mp_term_name": "pigmentation phenotype" | |
| }, | |
| "procedures": ["Ophthalmoscope"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005103", | |
| "mp_term_name": "abnormal retina pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915248", | |
| "marker_symbol": "Retreg3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Dexa-scan analysis"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010025", | |
| "mp_term_name": "decreased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915248", | |
| "marker_symbol": "Retreg3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology", "Ophthalmoscope"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005103", | |
| "mp_term_name": "abnormal retina pigmentation" | |
| }, | |
| { | |
| "mp_term_id": "MP:0001325", | |
| "mp_term_name": "abnormal retina morphology" | |
| }, | |
| { "mp_term_id": "MP:0002092", "mp_term_name": "abnormal eye morphology" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915255", | |
| "marker_symbol": "Naa10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005292", | |
| "mp_term_name": "improved glucose tolerance" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915255", | |
| "marker_symbol": "Naa10", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection", "Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002834", "mp_term_name": "decreased heart weight" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915276", | |
| "marker_symbol": "Pclaf", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915362", | |
| "marker_symbol": "Entr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004832", "mp_term_name": "enlarged ovary" }, | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0011874", "mp_term_name": "enlarged urinary bladder" } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915362", | |
| "marker_symbol": "Entr1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915384", | |
| "marker_symbol": "Upf3b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Intraperitoneal glucose tolerance test (IPGTT)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915415", | |
| "marker_symbol": "Fdx2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003917", "mp_term_name": "increased kidney weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915437", | |
| "marker_symbol": "Fam135a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002792", | |
| "mp_term_name": "abnormal retina vasculature morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010097", | |
| "mp_term_name": "abnormal retina blood vessel morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915501", | |
| "marker_symbol": "Babam1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002981", "mp_term_name": "increased liver weight" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915525", | |
| "marker_symbol": "Rpa1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Plasma Chemistry", "Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002702", | |
| "mp_term_name": "decreased circulating free fatty acids level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915528", | |
| "marker_symbol": "Ddx39a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001566", | |
| "mp_term_name": "increased circulating phosphate level" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915674", | |
| "marker_symbol": "Chn1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915775", | |
| "marker_symbol": "Evc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0030610", "mp_term_name": "absent teeth" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915918", | |
| "marker_symbol": "Klk5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Heart Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0004357", "mp_term_name": "long tibia" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915918", | |
| "marker_symbol": "Klk5", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": ["Hematology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005642", | |
| "mp_term_name": "decreased mean corpuscular hemoglobin concentration" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002590", | |
| "mp_term_name": "increased mean corpuscular volume" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010067", | |
| "mp_term_name": "increased red blood cell distribution width" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915958", | |
| "marker_symbol": "Rabl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915958", | |
| "marker_symbol": "Rabl2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002981", "mp_term_name": "increased liver weight" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915978", | |
| "marker_symbol": "Trp53inp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002989", "mp_term_name": "small kidney" }, | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1915978", | |
| "marker_symbol": "Trp53inp2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000599", "mp_term_name": "enlarged liver" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916043", | |
| "marker_symbol": "Rab3gap2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000443", | |
| "mp_term_name": "abnormal snout morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916125", | |
| "marker_symbol": "Tmcc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005370", | |
| "top_level_mp_term_name": "liver/biliary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005084", | |
| "mp_term_name": "abnormal gallbladder morphology" | |
| }, | |
| { "mp_term_id": "MP:0009342", "mp_term_name": "enlarged gallbladder" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916125", | |
| "marker_symbol": "Tmcc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916161", | |
| "marker_symbol": "Pygo2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E12.5"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000841", | |
| "mp_term_name": "abnormal hindbrain morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000897", | |
| "mp_term_name": "abnormal midbrain morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003720", | |
| "mp_term_name": "abnormal neural tube closure" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916161", | |
| "marker_symbol": "Pygo2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001914", "mp_term_name": "hemorrhage" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916192", | |
| "marker_symbol": "Chmp2b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0003642", "mp_term_name": "absent seminal vesicle" }, | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916192", | |
| "marker_symbol": "Chmp2b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916289", | |
| "marker_symbol": "Insig1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005278", | |
| "mp_term_name": "abnormal cholesterol homeostasis" | |
| }, | |
| { | |
| "mp_term_id": "MP:0003020", | |
| "mp_term_name": "decreased circulating chloride level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916351", | |
| "marker_symbol": "Ydjc", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": ["Clinical Chemistry"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001556", | |
| "mp_term_name": "increased circulating HDL cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005633", | |
| "mp_term_name": "increased circulating sodium level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002968", | |
| "mp_term_name": "increased circulating alkaline phosphatase level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005560", | |
| "mp_term_name": "decreased circulating glucose level" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916380", | |
| "marker_symbol": "Vps13b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005293", | |
| "mp_term_name": "impaired glucose tolerance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002966", | |
| "mp_term_name": "decreased circulating alkaline phosphatase level" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916380", | |
| "marker_symbol": "Vps13b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916380", | |
| "marker_symbol": "Vps13b", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0002060", "mp_term_name": "abnormal skin morphology" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916649", | |
| "marker_symbol": "1700025G04Rik", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916698", | |
| "marker_symbol": "Prss21", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916720", | |
| "marker_symbol": "Tmem127", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005397", | |
| "top_level_mp_term_name": "hematopoietic system phenotype" | |
| }, | |
| "procedures": [ | |
| "Hematology", | |
| "Spleen Immunophenotyping", | |
| "Whole blood peripheral blood leukocyte immunophenotyping", | |
| "Mesenteric Lymph Node Immunophenotyping" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010851", | |
| "mp_term_name": "decreased effector memory CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008078", | |
| "mp_term_name": "increased CD8-positive, alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013023", | |
| "mp_term_name": "decreased Ly6C high monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013436", | |
| "mp_term_name": "increased CD8-positive, naive alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012767", | |
| "mp_term_name": "increased KLRG1-positive NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008207", | |
| "mp_term_name": "decreased B-2 B cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000223", | |
| "mp_term_name": "decreased monocyte cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013427", | |
| "mp_term_name": "increased memory-marker NK cell number" | |
| }, | |
| { "mp_term_id": "MP:0005017", "mp_term_name": "decreased B cell number" }, | |
| { | |
| "mp_term_id": "MP:0008124", | |
| "mp_term_name": "decreased plasmacytoid dendritic cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012764", | |
| "mp_term_name": "increased alpha-beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013025", | |
| "mp_term_name": "increased Ly6C low monocyte number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013774", | |
| "mp_term_name": "decreased KLRG1-positive T-helper cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000222", | |
| "mp_term_name": "decreased neutrophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0012768", | |
| "mp_term_name": "decreased KLRG1-positive NK cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013426", | |
| "mp_term_name": "decreased memory-marker NK cell number" | |
| }, | |
| { "mp_term_id": "MP:0003179", "mp_term_name": "thrombocytopenia" }, | |
| { "mp_term_id": "MP:0005015", "mp_term_name": "increased T cell number" }, | |
| { | |
| "mp_term_id": "MP:0008074", | |
| "mp_term_name": "increased CD4-positive, alpha beta T cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008075", | |
| "mp_term_name": "decreased CD4-positive, alpha beta T cell number" | |
| }, | |
| { "mp_term_id": "MP:0008045", "mp_term_name": "decreased NK cell number" } | |
| ], | |
| "phenotype_count": 21 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916804", | |
| "marker_symbol": "Klhdc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005375", | |
| "top_level_mp_term_name": "adipose tissue phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0010024", | |
| "mp_term_name": "increased total body fat amount" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916804", | |
| "marker_symbol": "Klhdc2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011100", | |
| "mp_term_name": "preweaning lethality, complete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916818", | |
| "marker_symbol": "Vkorc1l1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005376", | |
| "top_level_mp_term_name": "homeostasis/metabolism phenotype" | |
| }, | |
| "procedures": [ | |
| "Intraperitoneal glucose tolerance test (IPGTT)", | |
| "Clinical Chemistry" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005419", | |
| "mp_term_name": "decreased circulating serum albumin level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005179", | |
| "mp_term_name": "decreased circulating cholesterol level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0013279", | |
| "mp_term_name": "increased fasting circulating glucose level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005278", | |
| "mp_term_name": "abnormal cholesterol homeostasis" | |
| }, | |
| { | |
| "mp_term_id": "MP:0005567", | |
| "mp_term_name": "decreased circulating total protein level" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000195", | |
| "mp_term_name": "decreased circulating calcium level" | |
| } | |
| ], | |
| "phenotype_count": 6 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916818", | |
| "marker_symbol": "Vkorc1l1", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003960", "mp_term_name": "increased lean body mass" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916837", | |
| "marker_symbol": "Pcgf3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { "mp_term_id": "MP:0001697", "mp_term_name": "abnormal embryo size" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916837", | |
| "marker_symbol": "Pcgf3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E18.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0008797", "mp_term_name": "facial cleft" }, | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" }, | |
| { | |
| "mp_term_id": "MP:0003743", | |
| "mp_term_name": "abnormal facial morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916947", | |
| "marker_symbol": "Camsap3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001258", "mp_term_name": "decreased body length" }, | |
| { "mp_term_id": "MP:0003961", "mp_term_name": "decreased lean body mass" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916947", | |
| "marker_symbol": "Camsap3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" }, | |
| { "mp_term_id": "MP:0001926", "mp_term_name": "female infertility" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916947", | |
| "marker_symbol": "Camsap3", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010768", | |
| "top_level_mp_term_name": "mortality/aging" | |
| }, | |
| "procedures": ["Viability Primary Screen"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011110", | |
| "mp_term_name": "preweaning lethality, incomplete penetrance" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916966", | |
| "marker_symbol": "Trip13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005371", | |
| "top_level_mp_term_name": "limbs/digits/tail phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002111", | |
| "mp_term_name": "abnormal tail morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002110", | |
| "mp_term_name": "abnormal digit morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916966", | |
| "marker_symbol": "Trip13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005390", | |
| "top_level_mp_term_name": "skeleton phenotype" | |
| }, | |
| "procedures": ["Body Composition (DEXA lean/fat)"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000063", | |
| "mp_term_name": "decreased bone mineral density" | |
| }, | |
| { "mp_term_id": "MP:0003795", "mp_term_name": "abnormal bone structure" }, | |
| { | |
| "mp_term_id": "MP:0010124", | |
| "mp_term_name": "decreased bone mineral content" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916966", | |
| "marker_symbol": "Trip13", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0010771", | |
| "top_level_mp_term_name": "integument phenotype" | |
| }, | |
| "procedures": ["Combined SHIRPA and Dysmorphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002075", | |
| "mp_term_name": "abnormal coat/hair pigmentation" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916974", | |
| "marker_symbol": "Rnaseh2a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001126", | |
| "mp_term_name": "abnormal ovary morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916974", | |
| "marker_symbol": "Rnaseh2a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Hematology", "Organ Weight"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000220", | |
| "mp_term_name": "increased monocyte cell number" | |
| }, | |
| { "mp_term_id": "MP:0004952", "mp_term_name": "increased spleen weight" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1916978", | |
| "marker_symbol": "Card11", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001147", "mp_term_name": "small testis" }, | |
| { | |
| "mp_term_id": "MP:0001146", | |
| "mp_term_name": "abnormal testis morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917004", | |
| "marker_symbol": "Fbxo7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Fertility of Homozygous Knock-out Mice"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001925", "mp_term_name": "male infertility" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917226", | |
| "marker_symbol": "Galk2", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Grip Strength"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0010052", "mp_term_name": "increased grip strength" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917264", | |
| "marker_symbol": "Kat14", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005382", | |
| "top_level_mp_term_name": "craniofacial phenotype" | |
| }, | |
| "procedures": ["X-ray"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000455", | |
| "mp_term_name": "abnormal maxilla morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002100", | |
| "mp_term_name": "abnormal tooth morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000438", | |
| "mp_term_name": "abnormal cranium morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917352", | |
| "marker_symbol": "Dnmbp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0003631", | |
| "top_level_mp_term_name": "nervous system phenotype" | |
| }, | |
| "procedures": [ | |
| "Eye Morphology", | |
| "Acoustic Startle and Pre-pulse Inhibition (PPI)" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0009141", | |
| "mp_term_name": "increased prepulse inhibition" | |
| }, | |
| { | |
| "mp_term_id": "MP:0008259", | |
| "mp_term_name": "abnormal optic disk morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917352", | |
| "marker_symbol": "Dnmbp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917352", | |
| "marker_symbol": "Dnmbp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005386", | |
| "top_level_mp_term_name": "behavior/neurological phenotype" | |
| }, | |
| "procedures": ["Open Field"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002574", | |
| "mp_term_name": "increased vertical activity" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917352", | |
| "marker_symbol": "Dnmbp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917352", | |
| "marker_symbol": "Dnmbp", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0003642", "mp_term_name": "absent seminal vesicle" }, | |
| { "mp_term_id": "MP:0002997", "mp_term_name": "enlarged seminal vesicle" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917428", | |
| "marker_symbol": "Abhd17c", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005378", | |
| "top_level_mp_term_name": "growth/size/body region phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000274", "mp_term_name": "enlarged heart" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917488", | |
| "marker_symbol": "Rnf168", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": [ | |
| "Gross Pathology and Tissue Collection", | |
| "Hematology", | |
| "Organ Weight" | |
| ], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0005011", | |
| "mp_term_name": "increased eosinophil cell number" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0004953", "mp_term_name": "decreased spleen weight" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 5 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917550", | |
| "marker_symbol": "Fuz", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005381", | |
| "top_level_mp_term_name": "digestive/alimentary phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000111", "mp_term_name": "cleft palate" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917550", | |
| "marker_symbol": "Fuz", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Morphology Embryo E14.5-E15.5"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0001914", "mp_term_name": "hemorrhage" } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917665", | |
| "marker_symbol": "Stk26", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005367", | |
| "top_level_mp_term_name": "renal/urinary system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002135", | |
| "mp_term_name": "abnormal kidney morphology" | |
| } | |
| ], | |
| "phenotype_count": 1 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917829", | |
| "marker_symbol": "Zc3h11a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005385", | |
| "top_level_mp_term_name": "cardiovascular system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000277", "mp_term_name": "abnormal heart shape" }, | |
| { | |
| "mp_term_id": "MP:0000266", | |
| "mp_term_name": "abnormal heart morphology" | |
| } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917829", | |
| "marker_symbol": "Zc3h11a", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005391", | |
| "top_level_mp_term_name": "vision/eye phenotype" | |
| }, | |
| "procedures": ["Eye Morphology"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0002699", | |
| "mp_term_name": "abnormal vitreous body morphology" | |
| }, | |
| { "mp_term_id": "MP:0001304", "mp_term_name": "cataract" } | |
| ], | |
| "phenotype_count": 2 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917858", | |
| "marker_symbol": "Btbd7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005379", | |
| "top_level_mp_term_name": "endocrine/exocrine gland phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { | |
| "mp_term_id": "MP:0002059", | |
| "mp_term_name": "abnormal seminal vesicle morphology" | |
| }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917858", | |
| "marker_symbol": "Btbd7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005387", | |
| "top_level_mp_term_name": "immune system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0000689", | |
| "mp_term_name": "abnormal spleen morphology" | |
| }, | |
| { "mp_term_id": "MP:0000709", "mp_term_name": "enlarged thymus" }, | |
| { "mp_term_id": "MP:0000691", "mp_term_name": "enlarged spleen" }, | |
| { | |
| "mp_term_id": "MP:0000703", | |
| "mp_term_name": "abnormal thymus morphology" | |
| } | |
| ], | |
| "phenotype_count": 4 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917858", | |
| "marker_symbol": "Btbd7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005388", | |
| "top_level_mp_term_name": "respiratory system phenotype" | |
| }, | |
| "procedures": ["Lung mechanics by forced oscillations"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0011045", | |
| "mp_term_name": "decreased lung elastance" | |
| }, | |
| { | |
| "mp_term_id": "MP:0002311", | |
| "mp_term_name": "abnormal inspiratory capacity" | |
| }, | |
| { | |
| "mp_term_id": "MP:0010895", | |
| "mp_term_name": "increased lung compliance" | |
| } | |
| ], | |
| "phenotype_count": 3 | |
| }, | |
| { | |
| "marker_accession_id": "MGI:1917858", | |
| "marker_symbol": "Btbd7", | |
| "top_level_phenotype_term": { | |
| "top_level_mp_term_id": "MP:0005389", | |
| "top_level_mp_term_name": "reproductive system phenotype" | |
| }, | |
| "procedures": ["Gross Pathology and Tissue Collection"], | |
| "phenotype_terms": [ | |
| { | |
| "mp_term_id": "MP:0001120 |
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