imports.01 | variables.styl

// ...
/**
 * Media sizes
 */
$media_aliases = {
  palm:       '(max-width: 480px)'
  lap:        '(min-width: 481px) and (max-width: 1023px)'
  lap-and-up: '(min-width: 481px)'
  portable:   '(max-width: 1023px)'
  desk:       '(min-width: 1024px)'
  desk-wide:  '(min-width: 1200px)'

  portrait:   '(orientation: portrait)'
  landscape:  '(orientation: landscape)'
}
// ...

imports.03 | mixin media.styl

$media_cache = {}

$media_aliases := {
  palm:       '(max-width: 480px)'
  lap:        '(min-width: 481px) and (max-width: 1023px)'
  lap-and-up: '(min-width: 481px)'
  portable:   '(max-width: 1023px)'
  desk:       '(min-width: 1024px)'
  desk-wide:  '(min-width: 1200px)'
}

media($condition) {
  $conditions = ()
  for $condition in arguments {
    $tmps = split(',', $condition)

    for $tmp in $tmps {
      $conditions[length($conditions)] = replace('^\s*', '', replace('\s*$', '', $tmp))
    }
  }

  helper($condition) {
    unless $media_cache[$condition] {
      $media_cache[$condition] = ();
    }
    push($media_cache[$condition], block);
  }

  for $condition in $conditions {
    $condition = replace('^\s*', '', replace('\s*$', '', $condition))
    $condition = replace('(\([^\)]+\)|[^\s\(]+)(\s*)', '$1✁', $condition)

    +helper($condition) {
      {selector() + ''} {
        {block}
      }
    }
  }
}

apply_media_cache() {
  for $medias, $blocks in $media_cache {
    $media_query = 'only screen';
    $medias = replace('^✁', '', replace('✁$', '', $medias))
    $medias = split('✁', $medias);

    for $media in $medias {
      $media_query += ' and ';
      $media = unquote($media_aliases[$media] || $media);
      $media = '(%s)' % $media unless match('\(', $media);
      $media_query += $media;
    }

    @media $media_query {
      for $block in $blocks {
        {$block}
      }
    }
  }
}

stylus.styl

// Must be first string
@import "imports/*";

/* Your styles */

// ...

a {
  color: #111;
  +media('palm,  lap', 'palm  lap', 'desk (min-width: 100px)') {
    color: #333;
  }
}

// ...

/* /Your styles */

// Must be last string
apply_media_cache();