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HiPiler Example: TAD calls of Arrowhead for chromosome 4 from Rao et al. (2014) GM12878. TADs are normalized to 60x60 bins to support piling, the diagonal is excluded for better of-diagonal patterns, and the matrix is capped at the 99-percentile against outliers. See https://flekschas.github.io/hipiler/ for a live demo.
{
"fgm": {
"fragmentsServer": "//higlass.io/api/v1/",
"fragmentsPrecision": 2,
"fragmentsDims": 60,
"fragmentsPadding": 50,
"fragmentsBaseRes": 1000,
"fragmentsPercentile": 99,
"fragmentsIgnoreDiags": 1,
"fragments": [
["chrom1", "start1", "end1", "strand1", "chrom2", "start2", "end2", "strand2", "dataset", "zoomOutLevel", "corner-score", "U-var", "L-var", "U-sign", "L-sign"],
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["chr4", 120990000, 122040000, "+", "chr4", 120990000, 122040000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.91873, 0.21624, 0.20299, 0.5561, 0.44426],
["chr4", 156875000, 157980000, "+", "chr4", 156875000, 157980000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.67065, 0.18521, 0.22376, 0.52899, 0.50041],
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["chr4", 73385000, 73905000, "+", "chr4", 73385000, 73905000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.0413, 0.14683, 0.10568, 0.52885, 0.7855],
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["chr4", 81275000, 81985000, "+", "chr4", 81275000, 81985000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.5324, 0.12061, 0.11874, 0.79072, 0.85003],
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["chr4", 95595000, 95970000, "+", "chr4", 95595000, 95970000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.64066, 0.094697, 0.11977, 0.40612, 0.47511],
["chr4", 162165000, 162665000, "+", "chr4", 162165000, 162665000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.182, 0.10458, 0.1077, 0.786, 0.4192],
["chr4", 180325000, 180735000, "+", "chr4", 180325000, 180735000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.79267, 0.097325, 0.11279, 0.40036, 0.45033],
["chr4", 79910000, 80310000, "+", "chr4", 79910000, 80310000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.0513, 0.11374, 0.089887, 0.83116, 0.40432],
["chr4", 72105000, 72540000, "+", "chr4", 72105000, 72540000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.69499, 0.099524, 0.10044, 0.50264, 0.50687],
["chr4", 114375000, 114850000, "+", "chr4", 114375000, 114850000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2748, 0.099311, 0.10055, 0.72637, 0.66645],
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["chr4", 152130000, 152580000, "+", "chr4", 152130000, 152580000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.8429, 0.12532, 0.074346, 0.57623, 0.54141],
["chr4", 142215000, 142695000, "+", "chr4", 142215000, 142695000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2743, 0.1032, 0.096334, 0.83333, 0.55122],
["chr4", 72050000, 72580000, "+", "chr4", 72050000, 72580000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.994, 0.09794, 0.10155, 0.64507, 0.65575],
["chr4", 90880000, 91235000, "+", "chr4", 90880000, 91235000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.1414, 0.0871, 0.11237, 0.53827, 0.71792],
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["chr4", 41260000, 41905000, "+", "chr4", 41260000, 41905000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2817, 0.093264, 0.10597, 0.79663, 0.69591],
["chr4", 124065000, 124640000, "+", "chr4", 124065000, 124640000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.1475, 0.10819, 0.090897, 0.55059, 0.62536],
["chr4", 20370000, 20700000, "+", "chr4", 20370000, 20700000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.1672, 0.10578, 0.093254, 0.53627, 0.71625],
["chr4", 119655000, 119815000, "+", "chr4", 119655000, 119815000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.303, 0.15315, 0.045552, 0.55859, 0.83984],
["chr4", 67965000, 68190000, "+", "chr4", 67965000, 68190000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.76642, 0.090793, 0.10785, 0.50791, 0.52767],
["chr4", 75785000, 76240000, "+", "chr4", 75785000, 76240000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.3452, 0.098493, 0.099566, 0.8599, 0.70966],
["chr4", 151195000, 151810000, "+", "chr4", 151195000, 151810000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.4681, 0.085103, 0.11237, 0.90825, 0.68244],
["chr4", 103550000, 104040000, "+", "chr4", 103550000, 104040000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.3712, 0.081331, 0.11598, 0.60891, 0.85298],
["chr4", 159205000, 159570000, "+", "chr4", 159205000, 159570000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.9817, 0.10248, 0.094696, 0.51126, 0.74099],
["chr4", 80820000, 81135000, "+", "chr4", 80820000, 81135000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.0481, 0.084546, 0.1116, 0.73891, 0.6381],
["chr4", 95185000, 95550000, "+", "chr4", 95185000, 95550000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.5384, 0.10786, 0.087151, 0.59685, 0.78979],
["chr4", 159615000, 160140000, "+", "chr4", 159615000, 160140000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.6415, 0.089573, 0.10482, 0.85232, 0.82475],
["chr4", 40035000, 40865000, "+", "chr4", 40035000, 40865000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.92725, 0.09525, 0.098754, 0.51589, 0.66497],
["chr4", 78875000, 79465000, "+", "chr4", 78875000, 79465000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.053, 0.11263, 0.080274, 0.8024, 0.53601],
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["chr4", 94735000, 95055000, "+", "chr4", 94735000, 95055000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2177, 0.095568, 0.096604, 0.63274, 0.61242],
["chr4", 162170000, 162600000, "+", "chr4", 162170000, 162600000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.99925, 0.093694, 0.098228, 0.78637, 0.42023],
["chr4", 40035000, 40740000, "+", "chr4", 40035000, 40740000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.91767, 0.091124, 0.09839, 0.5503, 0.61107],
["chr4", 130280000, 130605000, "+", "chr4", 130280000, 130605000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2379, 0.082951, 0.10307, 0.54441, 0.50822],
["chr4", 112990000, 113545000, "+", "chr4", 112990000, 113545000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2979, 0.09814, 0.087361, 0.80227, 0.58766],
["chr4", 8145000, 8600000, "+", "chr4", 8145000, 8600000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.94608, 0.061506, 0.1238, 0.55604, 0.60435],
["chr4", 173905000, 174375000, "+", "chr4", 173905000, 174375000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.5271, 0.090449, 0.094269, 0.81938, 0.69172],
["chr4", 16875000, 17480000, "+", "chr4", 16875000, 17480000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2162, 0.078881, 0.10572, 0.50246, 0.80355],
["chr4", 48570000, 48920000, "+", "chr4", 48570000, 48920000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.4586, 0.047827, 0.13375, 0.79347, 0.8849],
["chr4", 27045000, 27360000, "+", "chr4", 27045000, 27360000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.062, 0.094695, 0.085334, 0.7873, 0.44254],
["chr4", 122275000, 122695000, "+", "chr4", 122275000, 122695000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2005, 0.078967, 0.10035, 0.59807, 0.59127],
["chr4", 56200000, 56670000, "+", "chr4", 56200000, 56670000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.1767, 0.087767, 0.090518, 0.77954, 0.51471],
["chr4", 164400000, 164685000, "+", "chr4", 164400000, 164685000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.1124, 0.1011, 0.076592, 0.65148, 0.61453],
["chr4", 146120000, 146535000, "+", "chr4", 146120000, 146535000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.7206, 0.10154, 0.075158, 0.85772, 0.91754],
["chr4", 129215000, 129800000, "+", "chr4", 129215000, 129800000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.4392, 0.090789, 0.085804, 0.64202, 0.64027],
["chr4", 183365000, 183730000, "+", "chr4", 183365000, 183730000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.97114, 0.090128, 0.085932, 0.57733, 0.56456],
["chr4", 175285000, 175640000, "+", "chr4", 175285000, 175640000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.5471, 0.075273, 0.10064, 0.76512, 0.68725],
["chr4", 172315000, 172690000, "+", "chr4", 172315000, 172690000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.97823, 0.088898, 0.086959, 0.50142, 0.63514],
["chr4", 102080000, 102585000, "+", "chr4", 102080000, 102585000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.59088, 0.083501, 0.092068, 0.42118, 0.4302],
["chr4", 30370000, 30685000, "+", "chr4", 30370000, 30685000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.88324, 0.092525, 0.0814, 0.56052, 0.51368],
["chr4", 152045000, 152555000, "+", "chr4", 152045000, 152555000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.1241, 0.090373, 0.081938, 0.86697, 0.50519],
["chr4", 116145000, 116460000, "+", "chr4", 116145000, 116460000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.1194, 0.097656, 0.074638, 0.65625, 0.5373],
["chr4", 81990000, 82285000, "+", "chr4", 81990000, 82285000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.3267, 0.084722, 0.087081, 0.77356, 0.78851],
["chr4", 53410000, 53855000, "+", "chr4", 53410000, 53855000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2178, 0.095959, 0.074493, 0.65758, 0.84444],
["chr4", 140630000, 141200000, "+", "chr4", 140630000, 141200000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.342, 0.089433, 0.079162, 0.69652, 0.76147],
["chr4", 108915000, 109530000, "+", "chr4", 108915000, 109530000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.6749, 0.087841, 0.078257, 0.84815, 0.8748],
["chr4", 87405000, 87820000, "+", "chr4", 87405000, 87820000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.6868, 0.089828, 0.076058, 0.89605, 0.85075],
["chr4", 82320000, 82775000, "+", "chr4", 82320000, 82775000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.3624, 0.089998, 0.073854, 0.86957, 0.64203],
["chr4", 185180000, 185465000, "+", "chr4", 185180000, 185465000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.4287, 0.1173, 0.04649, 0.72291, 0.78448],
["chr4", 3570000, 3890000, "+", "chr4", 3570000, 3890000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 0.94578, 0.06818, 0.095386, 0.6377, 0.5498],
["chr4", 167520000, 167920000, "+", "chr4", 167520000, 167920000, "+", "CQMd6V_cRw6iCI_-Unl3PQ", 0, 1.2121, 0.086769, 0.076352, 0.61125, 0.79812],
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