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Install ExQuilla plugin for Thunderbird Using the Add-ons Manager. Alternatively, follow instructions from https://exquilla.zendesk.com/hc/en-us
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Restart Thunderbird
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Using the web browser, investigate if you can access the Exchange Server. Something like this: https://sync.my.company.com/EWS/Exchange.asmx
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If step 3 delivers some WSDL configuration, you are on the money.
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On Thunderbird, head to Tools > ExQuilla for Microsoft Exchange
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Try to replicate the web address and authentication parameters in order to make Thunderbird retrieve the WSDL configuration.
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If everything goes according to plan, Thunderbird will be able to receive and send emails as it would be expected.
Note: Licenses for ExQuilla are FREE and can be obtained at: http://mesquilla.net/buylicense.html