subdominiosmiddleware.py

from django.conf import settings
import re

class SubdominiosMiddleware:
    def process_request(self, request):
        request.domain = request.META['HTTP_HOST']
        request.subdomain = ''
        parts = request.domain.split('.')

        if len(parts) == 3 or (re.match("^localhost", parts[-1]) and len(parts) == 2):
            request.subdomain = parts[0]
            request.domain = '.'.join(parts[1:])
        
        # set the right urlconf
        if request.subdomain and request.subdomain != 'www' :
            
            request.urlconf = 'Casher.store.urls' #Ruta de tu URL