`ZIO#interruptible` can override a fiber's interruptibility inherited from its parent

ResourceAcquisitionTimeoutExample.scala

//> using scala "3.2.2"
//> using dep "dev.zio::zio:2.0.10"

import zio.*

object ResourceAcquisitionTimeoutExample extends ZIOAppDefault {
  val run =
    ZIO.debug("Running...") *>
    ZIO.acquireRelease(
      ZIO.debug("Acquired")
        .delay(3.seconds)
        .onInterrupt(ZIO.debug("Interrupt Detected"))
        .timeoutFail("Interrupted")(1.second)
        .interruptible // necessary for timeout
    )(_ => ZIO.debug("Released"))
}

Use Scala CLI to run

$ scala-cli https://gist.github.com/guersam/7bbe41d17ab025d323bc4e64b20217b8