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X = GXM | |
filename = paste0(data.dir,"tempo/gcta-run/gxm.grm") | |
ids = rnadata$sidno | |
write_GRMgz = function(X,filename,ids) | |
{ | |
#X[upper.tri(X,diag=TRUE)] | |
rmat = row(X) | |
cmat = col(X) | |
omat = cbind(cmat[upper.tri(cmat,diag=TRUE)],rmat[upper.tri(rmat,diag=TRUE)],ncol(rnamat),X[upper.tri(X,diag=TRUE)]) | |
write_tsv(data.frame(omat),path=filename,col_names = FALSE) | |
if(length(list.files(paste0(filename,".gz") ) )>0) system(paste0("rm ",filename,".gz")) | |
system(paste0("gzip ",filename)) | |
write_tsv(data.frame(ids,ids),path=paste0(filename,".id"),col_names = FALSE) | |
} | |
write_GRMgz(GXM,filename,ids) | |
## function in OmicKriging modified from original fro GCTA documentation | |
read_GRMBin <- | |
function (prefix, size = 4) | |
{ | |
sum_i <- function(i) { | |
return(sum(1:i)) | |
} | |
BinFileName <- paste(prefix, ".bin", sep = "") | |
NFileName <- paste(prefix, ".N.bin", sep = "") | |
IDFileName <- paste(prefix, ".id", sep = "") | |
id <- read.table(IDFileName) | |
n <- dim(id)[1] | |
BinFile <- file(BinFileName, "rb") | |
grm <- readBin(BinFile, n = n * (n + 1)/2, what = numeric(0), | |
size = size) | |
NFile <- file(NFileName, "rb") | |
N <- readBin(NFile, n = 1, what = numeric(0), size = size) | |
i <- sapply(1:n, sum_i) | |
close(BinFile) | |
close(NFile) | |
diag.elem <- grm[i] | |
off.diag.elem <- grm[-i] | |
X <- diag(diag.elem) | |
X[upper.tri(X, diag = FALSE)] <- off.diag.elem | |
X <- X + t(X) - diag(diag(X)) | |
rownames(X) <- id$V2 | |
colnames(X) <- id$V2 | |
return(X) | |
} | |
Another version of readGRMbin is here with slightly different output format https://ibg.colorado.edu/cdrom2022/day7/Answers/RR_WorkshopDay7.html | |
## this may be faster when the sample size is large. It uses the exact formula for sum_i rather than calculate with a for loop. But it didn't make a lot of difference when n~3100 | |
read_GRMBin_opt <- | |
function (prefix, size = 4) | |
{ | |
#sum_i <- function(i) { | |
# return(sum(1:i)) | |
#} | |
BinFileName <- paste(prefix, ".bin", sep = "") | |
NFileName <- paste(prefix, ".N.bin", sep = "") | |
IDFileName <- paste(prefix, ".id", sep = "") | |
id <- read.table(IDFileName) | |
n <- dim(id)[1] | |
BinFile <- file(BinFileName, "rb") | |
grm <- readBin(BinFile, n = n * (n + 1)/2, what = numeric(0), | |
size = size) | |
NFile <- file(NFileName, "rb") | |
N <- readBin(NFile, n = 1, what = numeric(0), size = size) | |
#i <- sapply(1:n, sum_i) | |
nvec <- 1:n | |
i <- nvec * (nvec + 1)/2 | |
close(BinFile) | |
close(NFile) | |
diag.elem <- grm[i] | |
off.diag.elem <- grm[-i] | |
X <- diag(diag.elem) | |
X[upper.tri(X, diag = FALSE)] <- off.diag.elem | |
X <- X + t(X) - diag(diag(X)) | |
rownames(X) <- id$V2 | |
colnames(X) <- id$V2 | |
return(X) | |
} |
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