C# create pipe client. Tested on Oracle VirtualBox and Visual Studio 2010.

pipe.cs

/*
  Create a Serial Port on VirtualBox and "Host Pipe" set its Port mode. After that check "Create Pipe" checkbox. 
  Then, "\\.\pipe\TestPipe" write on input of Port/File Path. After that, run your server code. 
  I wrote a little server code n C#. I found on internet something. 
  
  http://www.codeproject.com/Tips/492231/Csharp-Async-Named-Pipes
  http://www.codeproject.com/Tips/441841/Csharp-Named-Pipes-with-Async
  http://stackoverflow.com/questions/244367/c-sharp-3-5-connecting-named-pipe-across-network
  etc. My client code is following. 
*/

private void readButton_Click(object sender, EventArgs e)
{
    NamedPipeServerStream pipeServer = new NamedPipeServerStream(
        "TestPipe",
        PipeDirection.InOut,
        10,
        PipeTransmissionMode.Byte,
        PipeOptions.None
        );
    pipeServer.WaitForConnection();

    listBox1.Items.Add(pipeServer.ReadByte());
}

private void writeButton_Click(object sender, EventArgs e)
{
    NamedPipeClientStream pipeClient = new NamedPipeClientStream(
        ".",
        "TestPipe",
        PipeDirection.InOut);
    pipeClient.Connect();

    byte[] data = new byte[10];

    data[0] = 0x10;
    data[1] = 0x10;
    data[2] = 0x10;
    data[3] = 0x10;
    data[4] = 0x10;
    data[5] = 0x10;
    data[6] = 0x10;
    data[7] = 0x10;
    data[8] = 0x10;
    data[9] = 0x10;

    pipeClient.Write(data, 0, 9);

    pipeClient.Close();
}