Test for disabling autofocus on an Arducam 16MP camera.

focus-test.py

import cv2

cap = cv2.VideoCapture(0)

# You *must* grab at least frame before focus settings take effect.
# Try commenting and uncommenting the following line to test it
grabbed, frame = cap.read()

cap.set(cv2.CAP_PROP_AUTOFOCUS, 0) 
cap.set(cv2.CAP_PROP_FOCUS, 460)

while True:
    grabbed, frame = cap.read()
    cv2.imshow('frame', frame)
    if cv2.waitKey(1) & 0xFF == ord('q'):
        break