I recently asked the twitters for some podcasts recommendations. Here are some of the names people suggested along with some that I already listen to. Nobody has time to listen to all of these, but maybe you'll find something new.
All of the 5by5 podcasts are great. Lately I've been listening to these three:
Build & Analyze - iOS and mobile design/dev
Mac Power Users - lots of tips and useful utilities
Back to Work - Merlin Mann. 'Nuff said.
The Industry was another tech podcast that was recommended.
Iterate - the best design podcast I've come across
99% Invisible - fantastic discussions on design in meatspace
Creative Coding - visual programming (eg. Processing, three.js, openFrameworks, etc.)
Radiolab - You already listen to it, right?
You Look Nice Today - I'm not familiar with this one, but it looks like Merlin Mann is involved.
The Moth - "True stories told live"
CATO Institute Daily Podcast - for my fellow Libertarian-minded comrades
EconTalk - Economics is fascinating. For realz.
Hardcore History - Deep, deep dives into important historical events
The Lew Rockwell Show and Anti War Radio look like more Libertarian type shows that I'd enjoy.
The Flop House - making fun of bad movies
The Bugle - "Premium-Calibre Satirical Hogwash"