- LoopBack
- jQuery
- AngularJS
- Meteor
- KnockoutJS
- Zepto.js
- Backbone.js
- Opa
- ember.js
- Derby
- Polymer
- total.js
- Durandal
- Harp Platform
- Famo.us
- Koa
- Ractive.js
- Enyo
- Harp
- Pedestal
- Chaplin
- KnockbackJS
- PowerShell Pipeworks
- expressJS
- MontageJS
- jQuery Evergreen
- AmplifyJS
- Serenade.js
- SocketStream
- Agility.js
- Spine.js
- Batman.js
- Thorax
- Flight
- Vanilla JS
- Nombo
- Web Atoms
- Mojito
- hapi
- Geddy
- TowerJS
- flatiron
- LocomotiveJS
- COKE JS
- Partial.js
- Matador
- Frisby
Disclaimer: some of these may not be pure javascript, and/or may not strictly conform to the MVC pattern (although they should all be providing similar application development solutions)