config_amqp1.xml

<beans>
  <int-amqp:outbound-gateway
    amqp-template="amqpTemplate" 
    request-channel="requestChannel"
    reply-channel="resultChannel"
    routing-key="queue"/>
</beans>

config_amqp2.xml

<beans>
  <int-amqp:outbound-gateway
    amqp-template="amqpTemplate" 
    request-channel="requestChannelJson"
    reply-channel="resultChannelJson"
    routing-key="queue"/>
</beans>

<int:chain input-channel="requestChannel" output-channel="requestChannelJson">
  <int:object-to-json-transformer/>
</int:chain>
 
<int:chain input-channel="resultChannelJson" output-channel="resultChannel">
  <int:json-to-object-transformer type="your.package.to.Response"/>
</int:chain>

config_gateway.xml

<beans>
  <int:gateway service-interface="your.package.to.MyGateway"
               default-request-channel="requestChannel" 
               default-reply-channel="resultChannel"
               error-channel="errorChannel"/>
</beans>

MyGateway1.java

@Service
public interface MyGateway {

	@Gateway
	Response handle(@Payload Request request);

}

MyGateway2.java

@Service
public interface MyGateway {

	@Gateway
	Future<Response> handle(@Payload Request request);

}