tree-data.json

[
  {
    "id": 0,
    "value": "My Home",
    "label": "My Home",
    "children": [1, 31, 39]
  },
  {
    "id": 1,
    "value": "transcript_variant",
    "label": "Transcript variant",
    "children": [2, 19, 25, 29, 30],
    "parent": 0
  },
  {
    "id": 2,
    "value": "coding_variant",
    "label": "Coding variant",
    "children": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18],
    "parent": 1
  },
  {
    "id": 3,
    "value": "coding_sequence_variant",
    "label": "Coding sequence variant",
    "n": 18057,
    "description": "A sequence variant that changes the coding sequence",
    "parent": 2
  },
  {
    "id": 4,
    "value": "feature_elongation",
    "label": "Feature elongation",
    "n": 0,
    "description": "A sequence variant that causes the extension of a genomic feature, with regard to the reference sequence",
    "parent": 2
  },
  {
    "id": 5,
    "value": "feature_truncation",
    "label": "Feature truncation",
    "n": 0,
    "description": "A sequence variant that causes the reduction of a genomic feature, with regard to the reference sequence",
    "parent": 2
  },
  {
    "id": 6,
    "value": "frameshift_variant",
    "label": "Frameshift variant",
    "n": 506417,
    "description": "A sequence variant which causes a disruption of the translational reading frame, because the number of nucleotides inserted or deleted is not a multiple of three",
    "parent": 2
  },
  {
    "id": 7,
    "value": "incomplete_terminal_codon_variant",
    "label": "Incomplete terminal codon variant",
    "n": 3443,
    "description": "A sequence variant where at least one base of the final codon of an incompletely annotated transcript is changed",
    "parent": 2
  },
  {
    "id": 8,
    "value": "inframe_deletion",
    "label": "Inframe deletion",
    "n": 143302,
    "description": "An inframe non synonymous variant that deletes bases from the coding sequence",
    "parent": 2
  },
  {
    "id": 9,
    "value": "inframe_insertion",
    "label": "Inframe insertion",
    "n": 50924,
    "description": "An inframe non synonymous variant that inserts bases into in the coding sequence",
    "parent": 2
  },
  {
    "id": 10,
    "value": "missense_variant",
    "label": "Missense variant",
    "n": 12385885,
    "description": "A sequence variant, that changes one or more bases, resulting in a different amino acid sequence but where the length is preserved",
    "parent": 2
  },
  {
    "id": 11,
    "value": "NMD_transcript_variant",
    "label": "NMD transcript variant",
    "n": 20962310,
    "description": "A variant in a transcript that is the target of NMD",
    "parent": 2
  },
  {
    "id": 12,
    "value": "protein_altering_variant",
    "label": "Protein altering variant",
    "n": 3482,
    "description": "A sequence_variant which is predicted to change the protein encoded in the coding sequence",
    "parent": 2
  },
  {
    "id": 13,
    "value": "synonymous_variant",
    "label": "Synonymous variant",
    "n": 6340518,
    "description": "A sequence variant where there is no resulting change to the encoded amino acid",
    "parent": 2
  },
  {
    "id": 14,
    "value": "start_lost",
    "label": "Start lost",
    "n": 38719,
    "description": "A codon variant that changes at least one base of the canonical start codon",
    "parent": 2
  },
  {
    "id": 15,
    "value": "stop_gained",
    "label": "Stop gained",
    "n": 402831,
    "description": "A sequence variant whereby at least one base of a codon is changed, resulting in a premature stop codon, leading to a shortened transcript",
    "parent": 2
  },
  {
    "id": 16,
    "value": "stop_lost",
    "label": "Stop lost",
    "n": 16247,
    "description": "A sequence variant where at least one base of the terminator codon (stop) is changed, resulting in an elongated transcript",
    "parent": 2
  },
  {
    "id": 17,
    "value": "start_retained_variant",
    "label": "Start retained variant",
    "n": 585,
    "description": "A sequence variant where at least one base in the start codon is changed, but the start remains",
    "parent": 2
  },
  {
    "id": 18,
    "value": "stop_retained_variant",
    "label": "Stop retained variant",
    "n": 7754,
    "description": "A sequence variant where at least one base in the terminator codon is changed, but the terminator remains",
    "parent": 2
  },
  {
    "id": 19,
    "label": "Non-coding variant",
    "children": [20, 21, 22, 23, 24],
    "parent": 1
  },
  {
    "id": 20,
    "value": "3_prime_UTR_variant",
    "label": "3 prime UTR variant",
    "n": 4109311,
    "description": "A UTR variant of the 3' UTR",
    "parent": 19
  },
  {
    "id": 21,
    "value": "5_prime_UTR_variant",
    "label": "5 prime UTR variant",
    "description": "A UTR variant of the 5' UTR",
    "parent": 19,
    "children": [43]
  },
  {
    "id": 22,
    "value": "intron_variant",
    "label": "Intron variant",
    "n": 212366571,
    "description": "A transcript variant occurring within an intron",
    "parent": 19
  },
  {
    "id": 23,
    "value": "non_coding_transcript_exon_variant",
    "label": "Non coding transcript exon variant",
    "n": 7450628,
    "description": "A sequence variant that changes non-coding exon sequence in a non-coding transcript",
    "parent": 19
  },
  {
    "id": 24,
    "value": "non_coding_transcript_variant",
    "label": "Non coding transcript variant",
    "n": 52390424,
    "description": "A transcript variant of a non coding RNA gene",
    "parent": 19
  },
  {
    "id": 25,
    "label": "Splice variant",
    "children": [26, 27, 28],
    "parent": 1
  },
  {
    "id": 26,
    "value": "splice_acceptor_variant",
    "label": "Splice acceptor variant",
    "n": 172987,
    "description": "A splice variant that changes the 2 base region at the 3' end of an intron",
    "parent": 25
  },
  {
    "id": 27,
    "value": "splice_donor_variant",
    "label": "Splice donor variant",
    "n": 210311,
    "description": "A splice variant that changes the 2 base region at the 5' end of an intron",
    "parent": 25
  },
  {
    "id": 28,
    "value": "splice_region_variant",
    "label": "Splice region variant",
    "n": 2785532,
    "description": "A sequence variant in which a change has occurred within the region of the splice site, either within 1-3 bases of the exon or 3-8 bases of the intron",
    "parent": 25
  },
  {
    "id": 29,
    "value": "transcript_ablation",
    "label": "Transcript ablation",
    "n": 18,
    "description": "A feature ablation whereby the deleted region includes a transcript feature",
    "parent": 1
  },
  {
    "id": 30,
    "value": "transcript_amplification",
    "label": "Transcript amplification",
    "n": 0,
    "description": "A feature amplification of a region containing a transcript",
    "parent": 1
  },
  {
    "id": 31,
    "label": "Regulatory variant",
    "children": [32, 33, 34, 35, 36, 37, 38],
    "parent": 0
  },
  {
    "id": 32,
    "value": "mature_miRNA_variant",
    "label": "Mature miRNA variant",
    "n": 6871,
    "description": "A transcript variant located with the sequence of the mature miRNA",
    "parent": 31
  },
  {
    "id": 33,
    "value": "regulatory_region_ablation",
    "label": "Regulatory region ablation",
    "n": 0,
    "description": "A feature ablation whereby the deleted region includes a regulatory region",
    "parent": 31
  },
  {
    "id": 34,
    "value": "regulatory_region_amplification",
    "label": "Regulatory region amplification",
    "n": 0,
    "description": "A feature amplification of a region containing a regulatory region",
    "parent": 31
  },
  {
    "id": 35,
    "value": "regulatory_region_variant",
    "label": "Regulatory region variant",
    "n": 0,
    "description": "A sequence variant located within a regulatory region",
    "parent": 31
  },
  {
    "id": 36,
    "value": "TF_binding_site_variant",
    "label": "TF binding site variant",
    "n": 0,
    "description": "A sequence variant located within a transcription factor binding site",
    "parent": 31
  },
  {
    "id": 37,
    "value": "TFBS_ablation",
    "label": "TFBS ablation",
    "n": 0,
    "description": "A feature ablation whereby the deleted region includes a transcription factor binding site",
    "parent": 31
  },
  {
    "id": 38,
    "value": "TFBS_amplification",
    "label": "TFBS amplification",
    "n": 0,
    "description": "A feature amplification of a region containing a transcription factor binding site",
    "parent": 31
  },
  {
    "id": 39,
    "label": "Intergenic variant",
    "children": [40, 41, 42],
    "parent": 0
  },
  {
    "id": 40,
    "value": "downstream_gene_variant",
    "label": "Downstream gene variant",
    "n": 0,
    "description": "A sequence variant located 3' of a gene",
    "parent": 39
  },
  {
    "id": 41,
    "value": "intergenic_variant",
    "label": "Intergenic variant",
    "n": 38329053,
    "description": "A sequence variant located in the intergenic region, between genes",
    "parent": 39
  },
  {
    "id": 42,
    "value": "upstream_gene_variant",
    "label": "Upstream gene variant",
    "n": 0,
    "description": "A sequence variant located 5' of a gene",
    "parent": 39
  },
  {
    "id": 43,
    "value": "shine_dalgarno_sequence",
    "label": "Shine–Dalgarno sequence",
    "description": "ribosomal binding site in bacterial and archaeal messenger RNA",
    "parent": 21,
    "children": [44]
  },
  {
    "id": 44,
    "value": "pyrimidine",
    "label": "Pyrimidine",
    "description": "aromatic heterocyclic organic compound similar to pyridine",
    "parent": 43,
    "children": [45]
  },
  {
    "id": 45,
    "value": "pyrimidine2",
    "label": "Pyrimidine2 really long-long-long label",
    "description": "ribosomal binding site in bacterial and archaeal messenger RNA",
    "parent": 44,
    "children": [46]
  },
  {
    "id": 46,
    "value": "pyrimidine2",
    "label": "Pyrimidine2 really long-long-long label 2",
    "n": 1546374,
    "description": "ribosomal binding site in bacterial and archaeal messenger RNA",
    "parent": 45
  }
]