This script runs a python script in IronPython, and saves the various results.

TestPythonScript.cs

using System;
using System.IO;
using System.Text;
using IronPython.Hosting;
using IronPython.Runtime;
using IronPython.Runtime.Exceptions;
using Microsoft.Scripting;
using Microsoft.Scripting.Hosting;

/* This script runs a python script in IronPython, with a few parameters
 * and stores the various types of results in properties.
 * 
 * Not shown is: Setting variables (apart from argv), and capturing stderr.
*/

namespace AcceptanceTests
{
  public class CheckPythonScript
  {
    public void Execute()
    {
      ScriptEngine scriptEngine = Python.CreateEngine();
      ScriptSource scriptSource = scriptEngine
        .CreateScriptSourceFromFile(ScriptPath
                                    , Encoding.ASCII
                                    , SourceCodeKind.File);

      ScriptScope sys = scriptEngine.GetSysModule();
      var argv = new List {ScriptName, Arg1, Arg2, Arg3, Arg4, Arg5};
      sys.SetVariable("argv", argv);

      using (var memoryStream = new MemoryStream())
      {
        scriptEngine.Runtime.IO.SetOutput(memoryStream, new StreamWriter(memoryStream));
        try
        {
          object thing = scriptSource.Execute();
          if (thing != null)
            Result = thing.ToString();
        }
        catch (SystemExitException e)
        {
          object otherCode;
          ExitCode = e.GetExitCode(out otherCode);
          if (otherCode != null)
            OtherCode = otherCode.ToString();
        }
        catch (Exception e)
        {
          var eo = scriptEngine.GetService<ExceptionOperations>();
          ExceptionMessage = eo.FormatException(e);
        }
        finally
        {
          var length = (int) memoryStream.Length;
          var bytes = new byte[length];
          memoryStream.Seek(0, SeekOrigin.Begin);
          memoryStream.Read(bytes, 0, length);
          StdOut = Encoding.UTF8.GetString(bytes, 0, length).Trim();
        }
      }
    }
    public string ScriptPath { get; set; }
    public string Arg1 { get; set; }
    public string Arg2 { get; set; }
    public string Arg3 { get; set; }
    public string Arg4 { get; set; }
    public string Arg5 { get; set; }
    public string ScriptName { get; set; }
    public string Result { get; set; }
    public int ExitCode { get; set; }
    public string OtherCode { get; set; }
    public string ExceptionMessage { get; set; }
    public string StdOut { get; set; }
  }
}