Minimal .profile to configure things the way I like 'em...

.profile

# Command line prompt should be reasonable.
export PS1="$\w> "

# Reasonable coloring of directories, etc.
export CLICOLOR=1
export LSCOLORS=ExFxBxDxCxegedabagacad

# added by Anaconda3 5.2.0 installer
export PATH="/Users/mjl/anaconda3/bin:$PATH"

# Command history.
bind '"\e[A": history-search-backward'
bind '"\e[B": history-search-forward'

# Command line editing should be vim-like.
set -o vi

# Aliases...
alias ip='ipython --TerminalInteractiveShell.editing_mode=vi --no-confirm-exit'