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Tomasetti & Vogelstein (2015) Science 'bad luck of cancer' paper supplementary table S1. Finalised via Yaniv Erlich & Aaron Quinlan's draft clean-ups of the PDF supplement
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Cancer_type | Lifetime_cancer_incidence | Total_cells_tissue | Total_Stem_Cells | Stem_cell_divisions_per_year | Stem_cell_divisions_per_lifetime | LSCD | |
---|---|---|---|---|---|---|---|
ALL | 0.0041 | 3000000000000 | 135000000 | 12 | 960 | 129900000000 | |
BCC | 0.3 | 180000000000 | 5820000000 | 7.6 | 608 | 3550000000000 | |
CLL | 0.0052 | 3000000000000 | 135000000 | 12 | 960 | 129900000000 | |
Colorectal | 0.048 | 30000000000 | 200000000 | 73 | 5840 | 1168000000000 | |
Colorectal_FAP | 1 | 30000000000 | 200000000 | 73 | 5840 | 1168000000000 | |
Colorectal_Lynch | 0.5 | 30000000000 | 200000000 | 73 | 5840 | 1168000000000 | |
Duodenum_adenocarcinoma | 0.0003 | 680000000 | 4000000 | 24 | 1947 | 7796000000 | |
Duodenum_adenocarcinoma_with_FAP | 0.035 | 680000000 | 4000000 | 24 | 1947 | 7796000000 | |
Esophageal_squamous_cell_carcinoma | 0.001938 | 3240000000 | 846000 | 17.4 | 1390 | 1203000000 | |
Gallbladder_non_papillary_adenocarcinoma | 0.0028 | 160000000 | 1600000 | 0.584 | 47 | 78400000 | |
Glioblastoma | 0.00219 | 86400000000 | 135000000 | 0 | 0 | 270000000 | |
Head_neck_squamous_cell_carcinoma | 0.0138 | 16700000000 | 18500000 | 21.5 | 1720 | 31860000000 | |
Head_neck_squamous_cell_carcinoma_with_HPV-16 | 0.07935 | 16700000000 | 18500000 | 21.5 | 1720 | 31860000000 | |
Hepatocellular_carcinoma | 0.0071 | 241000000000 | 3010000000 | 0.9125 | 88 | 270900000000 | |
Hepatocellular_carcinoma_with_HCV | 0.071 | 241000000000 | 3010000000 | 0.9125 | 88 | 270900000000 | |
Lung_adenocarcinoma_(nonsmokers) | 0.0045 | 434000000000 | 1220000000 | 0.07 | 5.6 | 9272000000 | |
Lung_adenocarcinoma_(smokers) | 0.081 | 434000000000 | 1220000000 | 0.07 | 5.6 | 9272000000 | |
Medulloblastoma | 0.00011 | 85000000000 | 136000000 | 0 | 0 | 272000000 | |
Melanoma | 0.0203 | 3800000000 | 3800000000 | 2.48 | 199 | 763800000000 | |
Osteosarcoma | 0.00035 | 19000000000 | 4180000 | 0.067 | 5 | 29260000 | |
Osteosarcoma_of_arms | 0.00004 | 300000000 | 650000 | 0.067 | 5 | 4550000 | |
Osteosarcoma_of_head | 0.0000302 | 390000000 | 860000 | 0.067 | 5 | 6020000 | |
Osteosarcoma_legs | 0.00022 | 720000000 | 1590000 | 0.067 | 5 | 11130000 | |
Osteosarcoma_plevis | 0.00003 | 200000000 | 450000 | 0.067 | 5 | 3150000 | |
Ovarian_germ_cell | 0.000411 | 11000000 | 11000000 | 0 | 0 | 22000000 | |
Pancreatic_ductal_adenocarcinoma | 0.013589 | 167200000000 | 4180000000 | 1 | 80 | 342800000000 | |
Pancreatic_endocrine | 0.000194 | 2950000000 | 74000000 | 1 | 80 | 6068000000 | |
Small_intestine_adenocarcinoma | 0.0007 | 17000000000 | 100000000 | 36 | 2920 | 292200000000 | |
Testicular_germ_cell_cancer | 0.0037 | 21600000000 | 7200000 | 5.8 | 463 | 3348000000 | |
Thyroid_papillary/follicular_carcinoma | 0.01026 | 10000000000 | 65000000 | 0.087 | 7 | 558500000 | |
Thyroid_medullary_carcinoma | 0.000324 | 1000000000 | 6500000 | 0.087 | 7 | 558500000 |
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