It is hard to use Union in runtime type checks

runtime_union.py

>>> type(Union[int, str])
typing.Union
>>> type(Union[int, str]) == Union
Traceback (most recent call last):
  File "<stdin>", line 1, in <module>
  File "/Users/lucaswiman/.pyenv/versions/3.6/lib/python3.6/typing.py", line 760, in __eq__
    return self._subs_tree() == other
  File "/Users/lucaswiman/.pyenv/versions/3.6/lib/python3.6/typing.py", line 760, in __eq__
    return self._subs_tree() == other
  File "/Users/lucaswiman/.pyenv/versions/3.6/lib/python3.6/typing.py", line 760, in __eq__
    return self._subs_tree() == other
  [Previous line repeated 245 more times]
RecursionError: maximum recursion depth exceeded
>>> issubclass(Union[int, str], Union)
Traceback (most recent call last):
  File "<stdin>", line 1, in <module>
  File "/Users/lucaswiman/.pyenv/versions/3.6/lib/python3.6/typing.py", line 770, in __subclasscheck__
    raise TypeError("Unions cannot be used with issubclass().")
TypeError: Unions cannot be used with issubclass().
>>> from typing import _FinalTypingBase
>>> _FinalTypingBase in Union.mro()
Traceback (most recent call last):
  File "<stdin>", line 1, in <module>
AttributeError: '_Union' object has no attribute 'mro'
>>> type(Union[int, str]).mro()
[typing.Union, typing._FinalTypingBase, typing._TypingBase, <class 'object'>]

To clarify, this code is indicating that even special casing typing.Union in a runtime typechecker decorator is somewhat difficult. Is there a simpler way than Union in type(cls).mro()?