bench.js

if (!process.browser) var sodium = require('sodium-native')
var blake2b = require('blake2b')
var blake2bw = require('blake2b-wasm')
var BLAKE2s = require('blake2s-js')
var crypto = require('crypto')

var DATA_64KB = Buffer.alloc(65536)
var DATA_4KB = Buffer.alloc(4096)
var DATA_128B = Buffer.alloc(128)

blake2bw.ready(function (err) {
  if (err) throw new Error('WASM not supported')

  run('blake2s, 64kb', hashBlake2s, DATA_64KB, 10000)
  run('blake2b, 64kb', hashBlake2b, DATA_64KB, 10000)
  run('blake2b-wasm, 64kb', hashBlake2bWasm, DATA_64KB, 10000)
  if (!process.browser) run('sodium-native.generichash, 64kb', hashBlake2bSodium, DATA_64KB, 10000)
  run('sha256, 64kb', hashSha256, DATA_64KB, 10000)

  run('blake2s, 4kb', hashBlake2s, DATA_4KB, 10000)
  run('blake2b, 4kb', hashBlake2b, DATA_4KB, 10000)
  run('blake2b-wasm, 4kb', hashBlake2bWasm, DATA_4KB, 10000)
  if (!process.browser) run('sodium-native.generichash, 4kb', hashBlake2bSodium, DATA_4KB, 10000)
  run('sha256, 4kb', hashSha256, DATA_4KB, 10000)

  run('blake2s, 128b', hashBlake2s, DATA_128B, 10000)
  run('blake2b, 128b', hashBlake2b, DATA_128B, 10000)
  run('blake2b-wasm, 128b', hashBlake2bWasm, DATA_128B, 10000)
  if (!process.browser) run('sodium-native.generichash, 128b', hashBlake2bSodium, DATA_128B, 10000)
  run('sha256, 128b', hashSha256, DATA_128B, 10000)
})

function run (name, hash, data, runs) {
  console.log('Running bench: ' + name + ' (' + runs + ' runs)')

  var then = Date.now()

  for (var i = 0; i < runs; i++) {
    hash(data)
  }

  var delta = Date.now() - then
  console.log('Benchmark took ' + delta + 'ms, ' + Math.round(1000 * runs / delta) + ' hashes/s')
  console.log()
}

function hashBlake2s (input) {
  var hash = new BLAKE2s(32)
  hash.update(input)
  return hash.digest()
}

function hashBlake2b (input) {
  var out = new Buffer(32)
  blake2b(out, input)
  return out
}

function hashBlake2bWasm (input) {
  return blake2bw().update(input).digest()
}

function hashBlake2bSodium (input) {
  var out = new Buffer(32)
  sodium.crypto_generichash(out, input)
  return out
}

function hashSha256 (input) {
  return crypto.createHash('sha256').update(input).digest()
}

chrome-results.txt

Running bench: blake2s, 64kb (10000 runs)
Benchmark took 4329ms, 2310 hashes/s

Running bench: blake2b, 64kb (10000 runs)
Benchmark took 54959ms, 182 hashes/s

Running bench: blake2b-wasm, 64kb (10000 runs)
Benchmark took 3413ms, 2930 hashes/s

Running bench: sha256, 64kb (10000 runs)
Benchmark took 18201ms, 549 hashes/s

Running bench: blake2s, 4kb (10000 runs)
Benchmark took 374ms, 26738 hashes/s

Running bench: blake2b, 4kb (10000 runs)
Benchmark took 3329ms, 3004 hashes/s

Running bench: blake2b-wasm, 4kb (10000 runs)
Benchmark took 227ms, 44053 hashes/s

Running bench: sha256, 4kb (10000 runs)
Benchmark took 1285ms, 7782 hashes/s

Running bench: blake2s, 128b (10000 runs)
Benchmark took 122ms, 81967 hashes/s

Running bench: blake2b, 128b (10000 runs)
Benchmark took 108ms, 92593 hashes/s

Running bench: blake2b-wasm, 128b (10000 runs)
Benchmark took 21ms, 476190 hashes/s

Running bench: sha256, 128b (10000 runs)
Benchmark took 183ms, 54645 hashes/s

node-8-results.txt

Running bench: blake2s, 64kb (10000 runs)
Benchmark took 4272ms, 2341 hashes/s

Running bench: blake2b, 64kb (10000 runs)
Benchmark took 55845ms, 179 hashes/s

Running bench: blake2b-wasm, 64kb (10000 runs)
Benchmark took 3821ms, 2617 hashes/s

Running bench: sodium-native.generichash, 64kb (10000 runs)
Benchmark took 1114ms, 8977 hashes/s

Running bench: sha256, 64kb (10000 runs)
Benchmark took 2259ms, 4427 hashes/s

Running bench: blake2s, 4kb (10000 runs)
Benchmark took 348ms, 28736 hashes/s

Running bench: blake2b, 4kb (10000 runs)
Benchmark took 3535ms, 2829 hashes/s

Running bench: blake2b-wasm, 4kb (10000 runs)
Benchmark took 319ms, 31348 hashes/s

Running bench: sodium-native.generichash, 4kb (10000 runs)
Benchmark took 92ms, 108696 hashes/s

Running bench: sha256, 4kb (10000 runs)
Benchmark took 175ms, 57143 hashes/s

Running bench: blake2s, 128b (10000 runs)
Benchmark took 87ms, 114943 hashes/s

Running bench: blake2b, 128b (10000 runs)
Benchmark took 167ms, 59880 hashes/s

Running bench: blake2b-wasm, 128b (10000 runs)
Benchmark took 59ms, 169492 hashes/s

Running bench: sodium-native.generichash, 128b (10000 runs)
Benchmark took 13ms, 769231 hashes/s

Running bench: sha256, 128b (10000 runs)
Benchmark took 36ms, 277778 hashes/s

This is very cool. Gotta switch to node8 soon :-)
The node module benchmark https://benchmarkjs.com/ I great for these kind of benchmarks, runs the shortest amount of time to get statistically significant results and shows uncertainty of result.