simg.py

from tkinter import Button, Label, Tk, BOTTOM, TOP, Frame
from random import choice

root = Tk()
frame = Frame(root, width = 500, height = 500)
frame.pack(side=BOTTOM,expand = 1)

bottomframe = Frame(frame, width = 500)
bottomframe.pack()

topframe = Frame(root, height=100, width = 500, pady = 20)
topframe.pack()

gr = 10

colors = ["red", "blue"]

def restart():
    global p1s, p2s
    main()
    p1s = 0
    p2s = 0
    scoreupdate()

def exist():
    root.destroy()

def press(btn):
    global p1s, p2s
    if btn["bg"] in colors: pass
    else:
        color = choice(colors)
        btn["bg"] = color
        if color == "blue": p1s +=1
        elif color == "red": p2s +=1
        scoreupdate()

def main():
    for r in range(gr):
        for c in range(gr):
            btn = Button(bottomframe,width=3)
            btn.config(command = lambda arg=btn:press(arg))
            btn.grid(column=c, row=r)

def toolbar():
    Resetbtn = Button(topframe, text="Reset")
    Resetbtn.config(command = lambda :restart())
    Resetbtn.grid(column=1, row=0)

    Existbtn = Button(topframe, text="Exist")
    Existbtn.config(command = lambda :exist())
    Existbtn.grid(column=4, row=0)

def scoreupdate():
    p1 = Label(topframe,text="Player 1")
    p1.grid(column=0, row=1)

    p2 = Label(topframe,text="Player 2")
    p2.grid(column=3, row=1)

    p1score = Label(topframe,text=p1s, fg = "blue")
    p1score.grid(column=1, row=1)

    p2score = Label(topframe,text=p2s, fg = "red")
    p2score.grid(column=4, row=1)

p1s = 0
p2s = 0

toolbar()
scoreupdate()
main()
root.mainloop()