Emscripten's WebAssembly games non-intrusive auto-clicker by hijacking "JSEvents" object event handlers via browser debugger.

asm_autoClicker.js

{ // For copy/paste purpose...
	/* Usually, in most emscripten games "JSEvents" interface is private, therefore we expose it to global scope by using debugger (i.e Developer Tools)... */
	if (false) {
    /* Note: unityWebView.game.Module could be named differently (based on a game), for example like "gameInstance.Module" etc.. */
		// Copy this to the debugger and execute to stop at the breakpoint, where we will expose "JSEvents" to global scope.
    		debug(unityWebView.game.Module.SetFullscreen);
		unityWebView.game.Module.SetFullscreen();
		undebug(unityWebView.game.Module.SetFullscreen);
		//window.JSEvents = JSEvents; // expose this...
	}
}
// after successful JSEvents exposure, simply execute the code below which will take advantage of JSEvents to emulate mouse clicks on pre-programmed positions at custom period of time.
var findHandler = (function() {
	let handlerMap = {};

	for(let handlerId in JSEvents.eventHandlers) { 
		let handler = JSEvents.eventHandlers[handlerId];
		handlerMap[handler.eventTypeString] = handlerId;
    	}

	return function(handlerType) {
		return { handlerId: handlerMap[handlerType], handler: JSEvents.eventHandlers[handlerMap[handlerType]] };
	};
})();

var removeHandler = function(handlerType) {
	let eventHandler = findHandler(handlerType);
	if (eventHandler.handler)
		JSEvents._removeHandler(eventHandler.handlerId);
};

var autoClick = (function() {
	let mouseMoveHandler = findHandler("mousemove").handler;
	let mouseDownHandler = findHandler("mousedown").handler;
	let mouseUpHandler = findHandler("mouseup").handler;

	let target = unityWebView.game.Module.ctx.canvas;

	let mouseEvent = {
		 "screenX": 0,
		 "screenY": 0,
		 "clientX": 0,
		 "clientY": 0,
		 "ctrlKey": false,
		 "shiftKey": false,
		 "altKey": false,
		 "metaKey": false,
		 "button": 0,
		 "buttons": 0,
		 "movementX": 0,
		 "movementY": 0,
	};

	return function(x, y) {
		mouseEvent.screenX = mouseEvent.clientX = x;
		mouseEvent.screenY = mouseEvent.clientY = y;

		JSEvents.fillMouseEventData(JSEvents.mouseEvent, mouseEvent, target);
		unityWebView.game.Module["dynCall_iiii"](mouseMoveHandler.callbackfunc, 8, JSEvents.mouseEvent, 0); 
		unityWebView.game.Module["dynCall_iiii"](mouseDownHandler.callbackfunc, 5, JSEvents.mouseEvent, 0); 
		unityWebView.game.Module["dynCall_iiii"](mouseUpHandler.callbackfunc, 6, JSEvents.mouseEvent, 0);   
	};
})();

var bounds = { width: unityWebView.game.Module.canvas.width, height: unityWebView.game.Module.canvas.height };

var autoClicker = {
	interval: 85,
	timerId: autoClicker && autoClicker.timerId,
	timeoutClick: function(id, x, y, interval) {
		autoClicker[id] = autoClicker[id] || setTimeout(function() {
			autoClick(x, y);
			autoClicker[id] = null;
		}, interval);
	},
	init: function() {
		removeHandler("blur");
		clearInterval(autoClicker.timerId);
		autoClicker.timerId = setInterval(function() {
			/* Auto-Clicking positions goes here... */
			
			autoClick(bounds.width - 135, bounds.height - 278);

			autoClicker.timeoutClick("autoProgress_start", bounds.width + 105, bounds.height - 351, autoClicker.interval / 5);
			autoClicker.timeoutClick("autoProgress_next/finish", bounds.width + 116, bounds.height - 351, autoClicker.interval / 4);

			autoClicker.timeoutClick("level_up_Mizuki", bounds.width - 470, bounds.height - 527, autoClicker.interval / 3);
			autoClicker.timeoutClick("level_up_Bunny", bounds.width - 470, bounds.height - 418, autoClicker.interval / 2);
			autoClicker.timeoutClick("level_up_Estelle", bounds.width - 470, bounds.height - 312, autoClicker.interval / 1);
// 			autoClicker.timeoutClick("level_up_Megane", bounds.width - 470, bounds.height - 205, autoClicker.interval / 3);
// 			autoClicker.timeoutClick("level_up_Angela", bounds.width - 470, bounds.height - 96, autoClicker.interval / 2);
// 			autoClicker.timeoutClick("level_up_Lyrsa", bounds.width - 470, bounds.height + 12, autoClicker.interval / 1);

			autoClicker.timeoutClick("autoSkill_NeptunesTouch", bounds.width - 97, bounds.height - 15, 58 * 1000);
			autoClicker.timeoutClick("autoSkill_ExitingFlirt", bounds.width - 28, bounds.height - 15, 59 * 1000);
			autoClicker.timeoutClick("autoSkill_ManlySweat", bounds.width + 34, bounds.height - 15, 61 * 1000);
		
			autoClicker.timeoutClick("autoBonusClaimer", bounds.width + 210, bounds.height - 165, 30 * 1000);

		}, autoClicker.interval);
	}
};

/* Toggle ON/OFF Switch via 'Spacebar' and custom active zone */

var toggleState = true;

if (typeof printMousePos !== "undefined")
	document.removeEventListener("click", printMousePos);

if (typeof activeZone !== "undefined")
	document.removeEventListener("mousemove", activeZone);

if (typeof toggleButton !== "undefined")
	document.removeEventListener("keyup", toggleButton);

var printMousePos = function(mouseEvt) {
	console.log(`${mouseEvt.clientX}, ${mouseEvt.clientY}`);
	console.log(`autoClick(bounds.width - ${bounds.width - mouseEvt.clientX}, bounds.height - ${bounds.height - mouseEvt.clientY});`);
};

var activeZone = function(evt) {
	if (!toggleState)
		return false;

	if (evt.clientX < bounds.width / 1.5) {
		if (autoClicker.timerId) {
			clearInterval(autoClicker.timerId);
			autoClicker.timerId = null;
			console.log("[ActionZone] AutoClicker OFF!");
		}
	} else if (autoClicker.timerId == null) {
		autoClicker.init();
		console.log("[ActionZone] AutoClicker ON!");
	}	
};

var toggleButton = function(evt) {
	if (evt.keyCode == 32) {
		toggleState = !toggleState;
		if (toggleState && autoClicker.timerId == null) {
			autoClicker.init();
			console.log("[KeyPress] AutoClicker ON!");
		} else {
			clearInterval(autoClicker.timerId);
			autoClicker.timerId = null;
			console.log("[KeyPress] AutoClicker OFF!");
		}
	}
};

document.addEventListener("click", printMousePos);
document.addEventListener("mousemove", activeZone);
document.addEventListener("keyup", toggleButton);