If you're using Flat Rate shipping on Drupal Commerce, this update rule will prevent calculation of the customer shipping profile is empty.

commerce-flat-rate-calculation-rule.json

{ "commerce_shipping_method_flat_rate" : {
    "LABEL" : "Collect rates: Flat rate",
    "PLUGIN" : "reaction rule",
    "REQUIRES" : [ "rules", "commerce_shipping" ],
    "ON" : [ "commerce_shipping_collect_rates" ],
    "IF" : [
      { "entity_has_field" : {
          "entity" : [ "commerce-order" ],
          "field" : "commerce_customer_shipping"
        }
      },
      { "NOT data_is_empty" : { "data" : [ "commerce-order:commerce-customer-shipping" ] } }
    ],
    "DO" : [
      { "commerce_shipping_method_collect_rates" : {
          "shipping_method_name" : "flat_rate",
          "commerce_order" : [ "commerce-order" ]
        }
      }
    ]
  }
}