Use libsqlite3 directly from Python with ctypes: without using the built-in sqlite3 Python package, and without compiling anything

sqlite.py

# From https://stackoverflow.com/a/68876046/1319998, which is itself inspired by https://stackoverflow.com/a/68814418/1319998

from contextlib import contextmanager
from collections import namedtuple
from ctypes import cdll, byref, string_at, c_char_p, c_int, c_double, c_int64, c_void_p
from ctypes.util import find_library
from sys import platform


def query(db_file, sql, params=()):
    libsqlite3 = cdll.LoadLibrary(find_library('sqlite3'))
    libsqlite3.sqlite3_errstr.restype = c_char_p
    libsqlite3.sqlite3_errmsg.restype = c_char_p
    libsqlite3.sqlite3_column_name.restype = c_char_p
    libsqlite3.sqlite3_column_double.restype = c_double
    libsqlite3.sqlite3_column_int64.restype = c_int64
    libsqlite3.sqlite3_column_blob.restype = c_void_p
    libsqlite3.sqlite3_column_bytes.restype = c_int64
    SQLITE_ROW = 100
    SQLITE_DONE = 101
    SQLITE_TRANSIENT = -1
    SQLITE_OPEN_READWRITE = 0x00000002

    bind = {
        type(0): libsqlite3.sqlite3_bind_int64,
        type(0.0): libsqlite3.sqlite3_bind_double,
        type(''): lambda pp_stmt, i, value: libsqlite3.sqlite3_bind_text(pp_stmt, i, value.encode('utf-8'), len(value.encode('utf-8')), SQLITE_TRANSIENT),
        type(b''): lambda pp_stmt, i, value: libsqlite3.sqlite3_bind_blob(pp_stmt, i, value, len(value), SQLITE_TRANSIENT),
        type(None): lambda pp_stmt, i, _: libsqlite3.sqlite3_bind_null(pp_stmt, i),
    }

    extract = {
        1: libsqlite3.sqlite3_column_int64,
        2: libsqlite3.sqlite3_column_double,
        3: lambda pp_stmt, i: string_at(
            libsqlite3.sqlite3_column_blob(pp_stmt, i),
            libsqlite3.sqlite3_column_bytes(pp_stmt, i),
        ).decode(),
        4: lambda pp_stmt, i: string_at(
            libsqlite3.sqlite3_column_blob(pp_stmt, i),
            libsqlite3.sqlite3_column_bytes(pp_stmt, i),
        ),
        5: lambda pp_stmt, i: None,
    }

    def run(func, *args):
        res = func(*args)
        if res != 0:
            raise Exception(libsqlite3.sqlite3_errstr(res).decode())

    def run_with_db(db, func, *args):
        if func(*args) != 0:
            raise Exception(libsqlite3.sqlite3_errmsg(db).decode())

    @contextmanager
    def get_db(db_file):
        db = c_void_p()
        run(libsqlite3.sqlite3_open_v2, db_file.encode(), byref(db), SQLITE_OPEN_READWRITE, None)
        try:
            yield db
        finally:
            run_with_db(db, libsqlite3.sqlite3_close, db)

    @contextmanager
    def get_pp_stmt(db, sql):
        pp_stmt = c_void_p()
        run_with_db(db, libsqlite3.sqlite3_prepare_v3, db, sql.encode(), -1, 0, byref(pp_stmt), None)
        try:
            yield pp_stmt
        finally:
            run_with_db(db, libsqlite3.sqlite3_finalize, pp_stmt)

    with \
            get_db(db_file) as db, \
            get_pp_stmt(db, sql) as pp_stmt:

        for i, param in enumerate(params):
            run_with_db(db, bind[type(param)], pp_stmt, i + 1, param)

        row_constructor = namedtuple('Row', (
            libsqlite3.sqlite3_column_name(pp_stmt, i).decode()
            for i in range(0, libsqlite3.sqlite3_column_count(pp_stmt))
        ))

        while True:
            res = libsqlite3.sqlite3_step(pp_stmt)
            if res == SQLITE_DONE:
                break
            if res != SQLITE_ROW:
                raise Exception(libsqlite3.sqlite3_errstr(res).decode())

            yield row_constructor(*(
                extract[libsqlite3.sqlite3_column_type(pp_stmt, i)](pp_stmt, i)
                for i in range(0, len(row_constructor._fields))
            ))

P.S. I have gained a lot from your example /jsok/ above. That has offered a lot of hints :)
Thank you.

No problem!