Newrelic + Pyramid + uWSGI

gistfile1.py

    def wrap_wsgi_app(self, app):
        """Perform any necessary WSGI application wrapping.

        Wrap WSGI application to another WSGI application e.g. for the monitoring support. By default support New Relic.
        """

        if "NEW_RELIC_CONFIG_FILE" in os.environ:
            # Wrap for New Relic
            # libgcc_s.so.1 must be installed for pthread_cancel to work
            import newrelic.agent
            return newrelic.agent.wsgi_application()(app)

        return app

    def make_wsgi_app(self, sanity_check=True):
        """Create WSGI application from the current setup.

        :param sanity_check: True if perform post-initialization sanity checks.
        :return: WSGI application
        """
        
        # Let pyramid Configurator create initial app
        app = self.config.make_wsgi_app()
        
        # Carry the initializer around so we can access it in tests
        app.initializer = self

        app = self.wrap_wsgi_app(app)

        return app

uwsgi.ini

# the below is required by new relic. be sure to monitor your system
# memory since we're enabling threads
# https://newrelic.com/docs/python/python-agent-and-uwsgi
# http://uwsgi-docs.readthedocs.org/en/latest/Options.html
enable-threads = true
single-interpreter = true
lazy-apps = true

limit-as it not compatible with New Relic