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February 7, 2021 02:23
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Acronym as Sequence Logo
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rm(list=ls()) | |
library(ggseqlogo) | |
set.seed(1234) | |
myletters <- "CCBR" | |
# myletters <- "NCBR" | |
letter_vec <- unlist(strsplit(toupper(myletters),"")) | |
allletters <- unique(c("A","T","G","C",letter_vec)) | |
custom_mat <- matrix(0,nrow=length(allletters), ncol=length(letter_vec)) | |
rownames(custom_mat) <- allletters | |
big_size=1 | |
for (pos_idx in 1:ncol(custom_mat)) { | |
# pos_idx=1 | |
big_row=which(rownames(custom_mat) %in% letter_vec[pos_idx]) | |
little_rows=which(rownames(custom_mat) %in% setdiff(c("A","T","G","C"), letter_vec[pos_idx])) | |
custom_mat[big_row,pos_idx] <- big_size | |
little_min_size=big_size*0.05 | |
little_max_size=big_size*0.3 | |
custom_mat[little_rows,pos_idx] <- -runif(length(little_rows), little_min_size, little_max_size) | |
} | |
# Generate sequence logo | |
ggseqlogo(custom_mat, method='custom', namespace=allletters) + | |
ylab("")+theme(axis.text.x = element_blank(), | |
axis.text.y = element_blank(), | |
axis.ticks = element_blank()) |
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