Using WP_Query to create and customize multiple loops.

WP_Query-multiple-loops.php

 <?php // Loop 1
  $ rst_query = new WP_Query('cat=-1'); // exclude category
  while($ rst_query->have_posts()) : $ rst_query->the_post();
  ...
  endwhile;
  wp_reset_postdata(); // reset the query
  // Loop 2
  $second_query = new WP_Query('cat=-2'); // exclude category
  while($second_query->have_posts()) : $second_query->the_post();
  ...
  endwhile;
  wp_reset_postdata(); // reset the query
  // Loop 3
  $third_query = new WP_Query('cat=-3'); // exclude category
  while($third_query->have_posts()) : $third_query->the_post();
  ...
  endwhile;
  wp_reset_postdata(); // reset the query
  ?>