Using pygithub upload file | Advantage do not need to clone the repo.

commit _file_to_git.py

import base64
from github import Github
from github import InputGitTreeElement

g = Github("YOUR TOKEN")

# for org repo
# org = g.get_organization("NaimurDev")
# repo = org.get_repo('test_file')

# for personal repo
repo = g.get_user().get_repo('repo-name')

all_files = []
contents = repo.get_contents("")
print('contents')
print(contents)

file_list = [
    'hello2.txt',
]
file_names = [
    'hello2.txt',
]
commit_message = 'python commit'
master_ref = repo.get_git_ref('heads/main')
master_sha = master_ref.object.sha
base_tree = repo.get_git_tree(master_sha)
element_list = list()

for i, entry in enumerate(file_list):
    with open(entry) as input_file:
        data = input_file.read()
    if entry.endswith('.png'): # images must be encoded
        data = base64.b64encode(data)
    element = InputGitTreeElement(file_names[i], '100644', 'blob', data)
    element_list.append(element)

tree = repo.create_git_tree(element_list, base_tree)
parent = repo.get_git_commit(master_sha)
commit = repo.create_git_commit(commit_message, tree, [parent])
master_ref.edit(commit.sha)