Last active
December 8, 2017 09:29
-
-
Save nazgee/b6cd1a5cac9196e7dc362e16b7bbf82e to your computer and use it in GitHub Desktop.
plagiat
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| # -*- coding: utf-8 -*- | |
| #!/usr/local/bin/python2.7 | |
| import sys | |
| import csv | |
| from argparse import ArgumentParser | |
| from argparse import RawDescriptionHelpFormatter | |
| import traceback | |
| import itertools | |
| from fuzzywuzzy import fuzz | |
| # base comparison method -- any comparison method has to inherit it | |
| class Comparison(object): | |
| # TODO consider storing whole row, instead of a title | |
| # so a link to an article can be given when displaying results | |
| def __init__(self, titles, lowercase): | |
| self.titles = 2*[None] | |
| if (lowercase): | |
| self.titles[0] = titles[0].lower() | |
| self.titles[1] = titles[1].lower() | |
| else: | |
| self.titles[0] = titles[0] | |
| self.titles[1] = titles[1] | |
| def setMetric(self, metric): | |
| self.metric = metric | |
| def toString(self): | |
| s = "M=" + str(self.metric) + "\n" | |
| s = s + "- " + self.titles[0] + "\n" | |
| s = s + "- " + self.titles[1] + "\n" | |
| return s | |
| # comparison method #1 | |
| class ComparisonTokenSet(Comparison): | |
| def __init__(self, titles, lowercase): | |
| super(ComparisonTokenSet, self).__init__(titles, lowercase) | |
| super(ComparisonTokenSet, self).setMetric(fuzz.token_set_ratio(self.titles[0], self.titles[1])) | |
| # comparison method #2 | |
| class ComparisonTokenSort(Comparison): | |
| def __init__(self, titles, lowercase): | |
| super(ComparisonTokenSort, self).__init__(titles, lowercase) | |
| super(ComparisonTokenSort, self).setMetric(fuzz.token_sort_ratio(self.titles[0], self.titles[1])) | |
| # util function to get list of comparison methods - to verify cmdline validity | |
| def getComparisonMethods(): | |
| return map(lambda x: x.__name__, Comparison.__subclasses__()) | |
| # util function go get comparison object type based on a string passed from cmdline | |
| def getComparisonType(method): | |
| return next((x for x in Comparison.__subclasses__() if x.__name__ == method), None) | |
| def calculateCombinationsNumber(titlesNumber): | |
| return titlesNumber * (titlesNumber-1) / 2 | |
| # print iterations progress - https://stackoverflow.com/questions/3173320/text-progress-bar-in-the-console | |
| def printProgress(iteration, total, prefix='', suffix='', decimals=1, bar_length=100): | |
| """ | |
| Call in a loop to create terminal progress bar | |
| @params: | |
| iteration - Required : current iteration (Int) | |
| total - Required : total iterations (Int) | |
| prefix - Optional : prefix string (Str) | |
| suffix - Optional : suffix string (Str) | |
| decimals - Optional : positive number of decimals in percent complete (Int) | |
| bar_length - Optional : character length of bar (Int) | |
| """ | |
| str_format = "{0:." + str(decimals) + "f}" | |
| percents = str_format.format(100 * (iteration / float(total))) | |
| filled_length = int(round(bar_length * iteration / float(total))) | |
| bar = '█' * filled_length + '-' * (bar_length - filled_length) | |
| sys.stdout.write('\r%s |%s| %s%s %s' % (prefix, bar, percents, '%', suffix)), | |
| if iteration == total: | |
| sys.stdout.write('\n') | |
| sys.stdout.flush() | |
| # bells and whistles; reads .csv file, creates requested comparisons, and returns list of results | |
| def dumpstat(inputfile="pubmed_result.csv", limitinput=5, limitoutput=5, method='tokenset', lowercase=True): | |
| if method not in getComparisonMethods(): | |
| raise NotImplementedError("method " + method + " is not implemented") | |
| # list of titles limited to 'limitoutput' | |
| titles = [] | |
| # read .csv with entries | |
| with open(inputfile, mode="r") as fv: | |
| reader = csv.DictReader(fv) | |
| index = 0 | |
| for row in reader: | |
| # respect the limits | |
| index = index + 1 | |
| if (index > limitinput): | |
| break | |
| # skip malformed rows -- not sure why we're getting them | |
| if (row['Title'] == 'Title'): | |
| continue | |
| titles.append(row['Title']) | |
| # list of comparisons | |
| # FIXME can be lower than calculated if file is a small one | |
| totalComparisons = calculateCombinationsNumber(limitinput) | |
| comparisons = [] | |
| # TODO run comparisons in parallel | |
| index = 0 | |
| for pair in itertools.combinations(titles, r=2): | |
| c = getComparisonType(method)(pair, lowercase) | |
| # FIXME wasting a lot of memory here makes it impossible to work on big sets. | |
| # Maybe append only if better than worst of top 'limitinput' best ones | |
| # and use a fixed-width container capped to 'limitinput' | |
| comparisons.append(c) | |
| if ((index % 1000) == 0): | |
| printProgress(index, totalComparisons, "Working... ") | |
| index = index + 1 | |
| printProgress(totalComparisons, totalComparisons, "Compared!") | |
| # sort the comparison results, so better ones are first | |
| comparisons.sort(key=lambda x: x.metric, reverse=True) | |
| # display results | |
| index = 0 | |
| for c in comparisons: | |
| if (index > limitoutput): | |
| break | |
| print (c.toString()) | |
| index = index + 1 | |
| def main(argv=None): # IGNORE:C0111 | |
| '''Command line options.''' | |
| if argv is None: | |
| argv = sys.argv | |
| else: | |
| sys.argv.extend(argv) | |
| try: | |
| # Setup argument parser | |
| parser = ArgumentParser(formatter_class=RawDescriptionHelpFormatter) | |
| parser.add_argument("--verbose", dest="verbose", action='store_true', help="be verbose", default=True) | |
| parser.add_argument("--lowercase", dest="lowercase", action='store_true', help="make lowercase before comparison") | |
| parser.add_argument("--limitinput", dest="limitinput", type=int, help="number of titles to compare", default=sys.maxint) | |
| parser.add_argument("--limitoutput", dest="limitoutput", type=int, help="number of comparisons to return", default=10) | |
| parser.add_argument("--data", dest="filedata", nargs='?', help="file to read titles from [default: %(default)s]", default='pubmed_result.csv') | |
| parser.add_argument("--method", dest="method", nargs='?', help="comparison method to use, one of: {" + ', '.join(getComparisonMethods()) + "} [default: %(default)s]", default=getComparisonMethods()[0]) | |
| # Process arguments | |
| args = parser.parse_args() | |
| if (args.verbose): | |
| print "=====" | |
| print "data = " + args.filedata | |
| print "limitinput = " + str(args.limitinput) | |
| print "limitoutput = " + str(args.limitoutput) | |
| print "method = " + str(args.method) | |
| print "lowercase = " + str(args.lowercase) | |
| print "=====" | |
| print "max number of combinations to check: " + str(calculateCombinationsNumber(args.limitinput)) | |
| dumpstat(args.filedata, args.limitinput, args.limitoutput, args.method, args.lowercase) | |
| except KeyboardInterrupt: | |
| ### handle keyboard interrupt ### | |
| return 0 | |
| except Exception, e: | |
| traceback.print_exc() | |
| return 2 | |
| if __name__ == "__main__": | |
| sys.exit(main()) |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| michal@e6540:~/workspace/liclipse/plagiat$ time python ./plagiat.py --lowercase --limitoutput 300 --limitinput 5500 --method ComparisonTokenSet | |
| ===== | |
| data = pubmed_result.csv | |
| limitinput = 5500 | |
| limitoutput = 300 | |
| method = ComparisonTokenSet | |
| lowercase = True | |
| ===== | |
| max number of combinations to check: 15122250 | |
| Compared! |████████████████████████████████████████████████████████████████████████████████████████████████████| 100.0% | |
| M=100 | |
| - pathogenesis of lafora disease: transition of soluble glycogen to insoluble polyglucosan. | |
| - lafora disease. | |
| M=100 | |
| - cloning mice. | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| M=100 | |
| - cloning mice. | |
| - from cloning neural development genes to functional studies in mice, 30 years of advancements. | |
| M=100 | |
| - corrigendum: asymmetric parental genome engineering by cas9 during mouse meiotic exit. | |
| - asymmetric parental genome engineering by cas9 during mouse meiotic exit. | |
| M=100 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - correction of a genetic disease by crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| M=100 | |
| - erratum: genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer. | |
| - genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer. | |
| M=100 | |
| - abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in lafora disease. | |
| - lafora disease. | |
| M=100 | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| - cloning-free crispr. | |
| M=100 | |
| - the evolutionary capacitor hsp90 buffers the regulatory effects of mammalian endogenous retroviruses. | |
| - mammalian endogenous retroviruses. | |
| M=100 | |
| - liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency. | |
| - arginase-1 deficiency. | |
| M=100 | |
| - pronuclear injection-based targeted transgenesis. | |
| - one-step generation of multiple transgenic mouse lines using an improved pronuclear injection-based targeted transgenesis (i-pitt). | |
| M=100 | |
| - erratum to: trans effects of chromosome aneuploidies on dna methylation patterns in human down syndrome and mouse models. | |
| - trans effects of chromosome aneuploidies on dna methylation patterns in human down syndrome and mouse models. | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - erratum to: cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. | |
| - cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. | |
| M=100 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=100 | |
| - arginase-1 deficiency. | |
| - strategies to rescue the consequences of inducible arginase-1 deficiency in mice. | |
| M=100 | |
| - corrigendum: extensive microrna-mediated crosstalk between lncrnas and mrnas in mouse embryonic stem cells. | |
| - extensive microrna-mediated crosstalk between lncrnas and mrnas in mouse embryonic stem cells. | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=98 | |
| - activity-dependent dynamics of the transcription factor of camp-response element binding protein in cortical neurons revealed by single-molecule imaging. | |
| - activity-dependent dynamics of the transcription factor creb in cortical neurons revealed by single-molecule imaging. | |
| M=97 | |
| - erratum to: deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| - deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| M=96 | |
| - runx3 in immunity, inflammation and cancer. | |
| - runx3 at the interface of immunity, inflammation and cancer. | |
| M=96 | |
| - single-cell transcriptome and epigenomic reprogramming of cardiomyocyte-derived cardiac progenitor cells. | |
| - epigenomic reprogramming of adult cardiomyocyte-derived cardiac progenitor cells. | |
| M=95 | |
| - multicolor spectral analyses of mitotic and meiotic mouse chromosomes involved in multiple robertsonian translocations. ii. the nmri/cd and cd/ta hybrid strains. | |
| - multicolor spectral analyses of mitotic and meiotic mouse chromosomes involved in multiple robertsonian translocations. i. the cd/cremona hybrid strain. | |
| M=93 | |
| - crispr libraries and screening. | |
| - coralina: a universal method for the generation of grna libraries for crispr-based screening. | |
| M=93 | |
| - identification and functional analysis of long non-coding rnas in human and mouse early embryos based on single-cell transcriptome data. | |
| - identification and analysis of mouse non-coding rna using transcriptome data. | |
| M=93 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| M=92 | |
| - single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy. | |
| - postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy. | |
| M=92 | |
| - genome editing in mouse zygotes and embryonic stem cells by introducing sgrna/cas9 expressing plasmids. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=92 | |
| - a mouse model of hereditary coproporphyria identified in an enu mutagenesis screen. | |
| - enu mutagenesis in the mouse. | |
| M=92 | |
| - somatic genome editing goes viral. | |
| - pancreatic cancer modeling using retrograde viral vector delivery and in vivo crispr/cas9-mediated somatic genome editing. | |
| M=92 | |
| - toll-like receptors: potential targets for lupus treatment. | |
| - toll-like receptors in systemic lupus erythematosus: potential for personalized treatment. | |
| M=91 | |
| - circadian control of global transcription. | |
| - chip-seq and rna-seq methods to study circadian control of transcription in mammals. | |
| M=90 | |
| - continuous blockade of cxcr4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells. | |
| - ex vivo expansion of hematopoietic stem cells. | |
| M=90 | |
| - divergence patterns of genic copy number variation in natural populations of the house mouse (mus musculus domesticus) reveal three conserved genes with major population-specific expansions. | |
| - genomic copy number variation in mus musculus. | |
| M=89 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome database 2016. | |
| M=89 | |
| - role of the dna repair glycosylase ogg1 in the activation of murine splenocytes. | |
| - [the role of parp2 in dna repair]. | |
| M=89 | |
| - genome editing in mouse and rat by electroporation. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=89 | |
| - genome editing in mouse and rat by electroporation. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=89 | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=89 | |
| - cellular reprogramming, genome editing, and alternative crispr cas9 technologies for precise gene therapy of duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=89 | |
| - male infertility is responsible for nearly half of the extinction observed in the mouse collaborative cross. | |
| - genomes of the mouse collaborative cross. | |
| M=89 | |
| - muscle-specific crispr/cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=89 | |
| - mouse genome database (mgd)-2017: community knowledge resource for the laboratory mouse. | |
| - mouse genome database 2016. | |
| M=89 | |
| - the potential role of 8-oxoguanine dna glycosylase-driven dna base excision repair in exercise-induced asthma. | |
| - [the role of parp2 in dna repair]. | |
| M=89 | |
| - exploring novel candidate genes from the mouse genome informatics database: potential implications for avian migration research. | |
| - mouse genome database 2016. | |
| M=89 | |
| - mouse genome database 2016. | |
| - dbsuper: a database of super-enhancers in mouse and human genome. | |
| M=89 | |
| - mouse genome database 2016. | |
| - orthology for comparative genomics in the mouse genome database. | |
| M=89 | |
| - mouse genome database 2016. | |
| - mouse genome database: from sequence to phenotypes and disease models. | |
| M=89 | |
| - single-step generation of conditional knockout mouse embryonic stem cells. | |
| - rapid knockout and reporter mouse line generation and breeding colony establishment using eucomm conditional-ready embryonic stem cells: a case study. | |
| M=89 | |
| - a central role of trax in the atm-mediated dna repair. | |
| - [the role of parp2 in dna repair]. | |
| M=88 | |
| - combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models. | |
| - development of humanized mice in the age of genome editing. | |
| M=88 | |
| - an efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | |
| - generation and application of mouse-rat allodiploid embryonic stem cells. | |
| M=88 | |
| - genome editing in mouse and rat by electroporation. | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| M=88 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - [genome editing in mouse with crispr/cas system]. | |
| M=87 | |
| - replication study: melanoma genome sequencing reveals frequent prex2 mutations. | |
| - registered report: melanoma genome sequencing reveals frequent prex2 mutations. | |
| M=87 | |
| - generating mouse models using crispr-cas9-mediated genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=87 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=87 | |
| - genome editing in mice using tale nucleases. | |
| - genome editing in mouse spermatogonial stem/progenitor cells using engineered nucleases. | |
| M=86 | |
| - hotspots of de novo point mutations in induced pluripotent stem cells. | |
| - the number of point mutations in induced pluripotent stem cells and nuclear transfer embryonic stem cells depends on the method and somatic cell type used for their generation. | |
| M=86 | |
| - data on the effect of in utero exposure to polycyclic aromatic hydrocarbons on genome-wide patterns of dna methylation in lung tissues. | |
| - dna methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons. | |
| M=86 | |
| - crispr/cas9 - mediated precise targeted integration in vivo using a double cut donor with short homology arms. | |
| - homology-mediated end joining-based targeted integration using crispr/cas9. | |
| M=86 | |
| - effective biomedical document classification for identifying publications relevant to the mouse gene expression database (gxd). | |
| - the mouse gene expression database (gxd): 2017 update. | |
| M=86 | |
| - initial characterization of behavior and ketamine response in a mouse knockout of the post-synaptic effector gene anks1b. | |
| - the eif2a knockout mouse. | |
| M=86 | |
| - single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types. | |
| - evolution of the unspliced transcriptome. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - exome-wide single-base substitutions in tissues and derived cell lines of the constitutive fhit knockout mouse. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - beyond knockouts: the international knockout mouse consortium delivers modular and evolving tools for investigating mammalian genes. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - utilising the resources of the international knockout mouse consortium: the australian experience. | |
| M=86 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=86 | |
| - gene therapies that restore dystrophin expression for the treatment of duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=86 | |
| - generation and application of mammalian haploid embryonic stem cells. | |
| - generation and application of mouse-rat allodiploid embryonic stem cells. | |
| M=86 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=86 | |
| - comparative genomics: one for all. | |
| - orthology for comparative genomics in the mouse genome database. | |
| M=86 | |
| - comparative genomics: one for all. | |
| - application of comparative transcriptional genomics to identify molecular targets for pediatric ibd. | |
| M=86 | |
| - excavating the genome: large-scale mutagenesis screening for the discovery of new mouse models. | |
| - enu mutagenesis in the mouse. | |
| M=85 | |
| - landscape of dna methylation on the marsupial x. | |
| - influence of the prader-willi syndrome imprinting center on the dna methylation landscape in the mouse brain. | |
| M=85 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome database (mgd)-2017: community knowledge resource for the laboratory mouse. | |
| M=85 | |
| - an efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | |
| - generation and application of mammalian haploid embryonic stem cells. | |
| M=85 | |
| - functional validation of atf4 and gadd34 in neuro2a cells by crispr/cas9-mediated genome editing. | |
| - functional validation of tensin2 sh2-ptb domain by crispr/cas9-mediated genome editing. | |
| M=85 | |
| - generation of knock-in mouse by genome editing. | |
| - crispr/cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene. | |
| M=85 | |
| - generation of knock-in mouse by genome editing. | |
| - generation of an oocyte-specific cas9 transgenic mouse for genome editing. | |
| M=85 | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| - self-cloning crispr. | |
| M=85 | |
| - self-cloning crispr. | |
| - in vivo blunt-end cloning through crispr/cas9-facilitated non-homologous end-joining. | |
| M=85 | |
| - self-cloning crispr. | |
| - cloning-free crispr. | |
| M=85 | |
| - the role of mdm2 amplification and overexpression in tumorigenesis. | |
| - gene amplification-associated overexpression of the rna editing enzyme adar1 enhances human lung tumorigenesis. | |
| M=85 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=85 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=85 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=85 | |
| - in vivo blunt-end cloning through crispr/cas9-facilitated non-homologous end-joining. | |
| - cloning-free crispr. | |
| M=85 | |
| - assessment of microrna expression in mouse epididymal epithelial cells and spermatozoa by next generation sequencing. | |
| - next generation sequencing analysis reveals segmental patterns of microrna expression in mouse epididymal epithelial cells. | |
| M=85 | |
| - transcriptional response in mouse thyroid tissue after 211at administration: effects of absorbed dose, initial dose-rate and time after administration. | |
| - transcriptional response in normal mouse tissues after i.v. (211)at administration - response related to absorbed dose, dose rate, and time. | |
| M=84 | |
| - amino acid substitutions associated with avian h5n6 influenza a virus adaptation to mice. | |
| - amino acid substitutions involved in the adaptation of a novel highly pathogenic h5n2 avian influenza virus in mice. | |
| M=84 | |
| - genome editing in mouse and rat by electroporation. | |
| - efficient crispr/cas9-mediated genome editing in mice by zygote electroporation of nuclease. | |
| M=84 | |
| - p53 and tap63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes. | |
| - the atm signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. | |
| M=84 | |
| - genomes of the mouse collaborative cross. | |
| - collaborative cross and diversity outbred data resources in the mouse phenome database. | |
| M=84 | |
| - genomes of the mouse collaborative cross. | |
| - informatics resources for the collaborative cross and related mouse populations. | |
| M=84 | |
| - complete genome sequence of acinetobacter sp. strain ncu2d-2 isolated from a mouse. | |
| - complete genome sequence of turicibacter sp. strain h121, isolated from the feces of a contaminated germ-free mouse. | |
| M=84 | |
| - genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. | |
| - the genetic architecture of nafld among inbred strains of mice. | |
| M=83 | |
| - pd-l1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome informatics (mgi) resource: genetic, genomic, and biological knowledgebase for the laboratory mouse. | |
| M=83 | |
| - human t-cell leukemia virus type 1 infection and adult t-cell leukemia. | |
| - effects of expressing human t-cell leukemia virus type 1 (htlv-i) oncoprotein tax on dok1, dok2 and dok3 gene expression in mice. | |
| M=83 | |
| - human t-cell leukemia virus type 1 infection and adult t-cell leukemia. | |
| - human t-cell leukemia virus type 1 (htlv-1) tax requires cadm1/tslc1 for inactivation of the nf-κb inhibitor a20 and constitutive nf-κb signaling. | |
| M=83 | |
| - shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the united states. | |
| - zinc and diabetes. | |
| M=83 | |
| - a five-repeat micro-dystrophin gene ameliorated dystrophic phenotype in the severe dba/2j-mdx model of duchenne muscular dystrophy. | |
| - jagged 1 rescues the duchenne muscular dystrophy phenotype. | |
| M=83 | |
| - engineered epidermal progenitor cells can correct diet-induced obesity and diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - tex19.1 promotes spo11-dependent meiotic recombination in mouse spermatocytes. | |
| - the atm signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. | |
| M=83 | |
| - identification and characterization of a foxa2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls gckr expression in liver cells. | |
| - zinc and diabetes. | |
| M=83 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| M=83 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=83 | |
| - expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion. | |
| - zinc and diabetes. | |
| M=83 | |
| - targeted dna methylation in pericentromeres with genome editing-based artificial dna methyltransferase. | |
| - editing dna methylation in the mammalian genome. | |
| M=83 | |
| - using hescs to probe the interaction of the diabetes-associated genes cdkal1 and mt1e. | |
| - zinc and diabetes. | |
| M=83 | |
| - dna modifications and alzheimer's disease. | |
| - modifiers and readers of dna modifications and their impact on genome structure, expression, and stability in disease. | |
| M=83 | |
| - the zinc finger e-box-binding homeobox 1 (zeb1) promotes the conversion of mouse fibroblasts into functional neurons. | |
| - chemical conversion of mouse fibroblasts into functional dopaminergic neurons. | |
| M=83 | |
| - genetic and small molecule disruption of the aid/rad51 axis similarly protects nonobese diabetic mice from type 1 diabetes through expansion of regulatory b lymphocytes. | |
| - zinc and diabetes. | |
| M=83 | |
| - long-term alterations to dna methylation as a biomarker of prenatal alcohol exposure: from mouse models to human children with fetal alcohol spectrum disorders. | |
| - associative dna methylation changes in children with prenatal alcohol exposure. | |
| M=83 | |
| - genetics of obesity: can an old dog teach us new tricks? | |
| - systems genetics of obesity. | |
| M=83 | |
| - the transcription factor nfatc2 regulates β-cell proliferation and genes associated with type 2 diabetes in mouse and human islets. | |
| - zinc and diabetes. | |
| M=83 | |
| - systems genetics of obesity. | |
| - visualization of results from systems genetics studies in chromosomal context. | |
| M=83 | |
| - systems genetics of obesity. | |
| - a suite of tools for biologists that improve accessibility and visualization of large systems genetics datasets: applications to the hybrid mouse diversity panel. | |
| M=83 | |
| - systems genetics of obesity. | |
| - defining the influence of germline variation on metastasis using systems genetics approaches. | |
| M=83 | |
| - systems genetics of obesity. | |
| - the hybrid mouse diversity panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. | |
| M=83 | |
| - systems genetics of obesity. | |
| - genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. | |
| M=83 | |
| - systems genetics of obesity. | |
| - systems genetics of intravenous cocaine self-administration in the bxd recombinant inbred mouse panel. | |
| M=83 | |
| - systems genetics of obesity. | |
| - application of quantitative metabolomics in systems genetics in rodent models of complex phenotypes. | |
| M=83 | |
| - systems genetics of obesity. | |
| - a systems genetics study of swine illustrates mechanisms underlying human phenotypic traits. | |
| M=83 | |
| - systems genetics of obesity. | |
| - systems genetics identifies sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus. | |
| M=83 | |
| - emerging roles of glis3 in neonatal diabetes, type 1 and type 2 diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - differential gene dosage effects of diabetes-associated gene glis3 in pancreatic β cell differentiation and function. | |
| - zinc and diabetes. | |
| M=83 | |
| - transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms. | |
| - enu mutagenesis in the mouse. | |
| M=83 | |
| - inhibition of dna methyltransferase 1 increases nuclear receptor subfamily 4 group a member 1 expression and decreases blood glucose in type 2 diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - microinjection-based generation of mutant mice with a double mutation and a 0.5 mb deletion in their genome by the crispr/cas9 system. | |
| - generation of site-specific mutant mice using the crispr/cas9 system. | |
| M=83 | |
| - an integrative study identifies kcnc2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the korean population. | |
| - zinc and diabetes. | |
| M=83 | |
| - structural organization of the inactive x chromosome in the mouse. | |
| - bipartite structure of the inactive mouse x chromosome. | |
| M=83 | |
| - zinc and diabetes. | |
| - serotonin as a new therapeutic target for diabetes mellitus and obesity. | |
| M=83 | |
| - zinc and diabetes. | |
| - unexpected partial correction of metabolic and behavioral phenotypes of alzheimer's app/psen1 mice by gene targeting of diabetes/alzheimer's-related sorcs1. | |
| M=83 | |
| - zinc and diabetes. | |
| - type 1 diabetes genetic susceptibility and dendritic cell function: potential targets for treatment. | |
| M=83 | |
| - zinc and diabetes. | |
| - genetic association of long-chain acyl-coa synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis. | |
| M=83 | |
| - zinc and diabetes. | |
| - a20 inhibits β-cell apoptosis by multiple mechanisms and predicts residual β-cell function in type 1 diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - genetic architecture of early pre-inflammatory stage transcription signatures of autoimmune diabetes in the pancreatic lymph nodes of the nod mouse reveals significant gene enrichment on chromosomes 6 and 7. | |
| M=83 | |
| - zinc and diabetes. | |
| - ptpn22 and cd2 variations are associated with altered protein expression and susceptibility to type 1 diabetes in nonobese diabetic mice. | |
| M=83 | |
| - zinc and diabetes. | |
| - phenotypic characterization of mice carrying homozygous deletion of klf11, a gene in which mutations cause human neonatal and mody vii diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - ptprd silencing by dna hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - the pathogenic role of persistent milk signaling in mtorc1- and milk-microrna-driven type 2 diabetes mellitus. | |
| M=83 | |
| - sequence diversity, intersubgroup relationships, and origins of the mouse leukemia gammaretroviruses of laboratory and wild mice. | |
| - origins of the endogenous and infectious laboratory mouse gammaretroviruses. | |
| M=83 | |
| - rag2 and xlf/cernunnos interplay reveals a novel role for the rag complex in dna repair. | |
| - [the role of parp2 in dna repair]. | |
| M=83 | |
| - nuclear localization of the dna repair scaffold xrcc1: uncovering the functional role of a bipartite nls. | |
| - [the role of parp2 in dna repair]. | |
| M=83 | |
| - genomic copy number variation in mus musculus. | |
| - connecting anxiety and genomic copy number variation: a genome-wide analysis in cd-1 mice. | |
| M=83 | |
| - enu mutagenesis in the mouse. | |
| - simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells. | |
| M=83 | |
| - enu mutagenesis in the mouse. | |
| - piggybac transposon-based insertional mutagenesis in mouse haploid embryonic stem cells. | |
| M=82 | |
| - genome-wide discovery of long intergenic noncoding rnas and their epigenetic signatures in the rat. | |
| - mutations in the noncoding genome. | |
| M=82 | |
| - replication stress in hematopoietic stem cells in mouse and man. | |
| - a short g1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. | |
| M=82 | |
| - complete genome sequence of a strain of bifidobacterium pseudolongum isolated from mouse feces and associated with improved organ transplant outcome. | |
| - complete genome sequence of acinetobacter sp. strain ncu2d-2 isolated from a mouse. | |
| M=82 | |
| - highly variable genomic landscape of endogenous retroviruses in the c57bl/6j inbred strain, depending on individual mouse, gender, organ type, and organ location. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - a modifier of huntington's disease onset at the mlh1 locus. | |
| - chromosome substitution strain assessment of a huntington's disease modifier locus. | |
| M=82 | |
| - a14 comprehensive characterisation and evolutionary analysis of endogenous retroviruses in the mouse genome. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - functional validation of atf4 and gadd34 in neuro2a cells by crispr/cas9-mediated genome editing. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=82 | |
| - the hope and hype of crispr-cas9 genome editing: a review. | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| M=82 | |
| - detection of rna polymerase ii in mouse embryos during zygotic genome activation using immunocytochemistry. | |
| - rna fish to study zygotic genome activation in early mouse embryos. | |
| M=82 | |
| - identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts. | |
| - generation of integration-free induced neural stem cells from mouse fibroblasts. | |
| M=82 | |
| - comparative dynamics of 5-methylcytosine reprogramming and tet family expression during preimplantation mammalian development in mouse and sheep. | |
| - maternal sin3a regulates reprogramming of gene expression during mouse preimplantation development. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - crispr/cas9 mediated genome editing in es cells and its application for chimeric analysis in mice. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - crispr/cas9-mediated insertion of loxp sites in the mouse dock7 gene provides an effective alternative to use of targeted embryonic stem cells. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - generating crispr/cas9 mediated monoallelic deletions to study enhancer function in mouse embryonic stem cells. | |
| M=82 | |
| - integration and fixation preferences of human and mouse endogenous retroviruses uncovered with functional data analysis. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - precision cancer mouse models through genome editing with crispr-cas9. | |
| M=82 | |
| - generating mouse models using crispr-cas9-mediated genome editing. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=82 | |
| - improved genome editing efficiency and flexibility using modified oligonucleotides with talen and crispr-cas9 nucleases. | |
| - genome editing in mice using tale nucleases. | |
| M=82 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - insertion of sequences at the original provirus integration site of mouse rosa26 locus using the crispr/cas9 system. | |
| M=82 | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| - generation of site-specific mutant mice using the crispr/cas9 system. | |
| M=82 | |
| - the role of human endogenous retroviruses in brain development and function. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - genomic landscapes of endogenous retroviruses unveil intricate genetics of conventional and genetically-engineered laboratory mouse strains. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - trim33 binds and silences a class of young endogenous retroviruses in the mouse testis; a novel component of the arms race between retrotransposons and the host genome. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - towards autotrophic tissue engineering: photosynthetic gene therapy for regeneration. | |
| - photosynthetic biomaterials: a pathway towards autotrophic tissue engineering. | |
| M=82 | |
| - mutations in the noncoding genome. | |
| - assessing recent selection and functionality at long noncoding rna loci in the mouse genome. | |
| M=82 | |
| - comprehensive dna methylation analysis of retrotransposons in male germ cells. | |
| - locus-specific dna methylation analysis of retrotransposons in es, somatic and cancer cells using high-throughput targeted repeat element bisulfite sequencing. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the histone methyltransferase setdb1 represses endogenous and exogenous retroviruses in b lymphocytes. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the krab zinc finger protein zfp809 is required to initiate epigenetic silencing of endogenous retroviruses. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the decline of human endogenous retroviruses: extinction and survival. | |
| M=81 | |
| - landscape of dna methylation on the marsupial x. | |
| - erratum to: deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| M=81 | |
| - landscape of dna methylation on the marsupial x. | |
| - deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| M=81 | |
| - knockdown of heat shock proteins hspa6 (hsp70b') and hspa1a (hsp70-1) sensitizes differentiated human neuronal cells to cellular stress. | |
| - differential targeting of hsp70 heat shock proteins hspa6 and hspa1a with components of a protein disaggregation/refolding machine in differentiated human neuronal cells following thermal stress. | |
| M=81 | |
| - knockdown of heat shock proteins hspa6 (hsp70b') and hspa1a (hsp70-1) sensitizes differentiated human neuronal cells to cellular stress. | |
| - dynamics of the association of heat shock protein hspa6 (hsp70b') and hspa1a (hsp70-1) with stress-sensitive cytoplasmic and nuclear structures in differentiated human neuronal cells. | |
| M=81 | |
| - replication stress in hematopoietic stem cells in mouse and man. | |
| - ssb1 and ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress. | |
| M=81 | |
| - distinguishing states of arrest: genome-wide descriptions of cellular quiescence using chip-seq and rna-seq analysis. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - role of rad51ap1 in homologous recombination dna repair and carcinogenesis. | |
| - [the role of parp2 in dna repair]. | |
| M=81 | |
| - x chromosome evolution in cetartiodactyla. | |
| - a genome survey sequencing of the java mouse deer (tragulus javanicus) adds new aspects to the evolution of lineage specific retrotransposons in ruminantia (cetartiodactyla). | |
| M=81 | |
| - standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of kctd1 (i27n) mutant mice. | |
| - generation and standardized, systemic phenotypic analysis of pou3f3l423p mutant mice. | |
| M=81 | |
| - subpial adeno-associated virus 9 (aav9) vector delivery in adult mice. | |
| - adeno-associated virus vector mediated delivery of the hbv genome induces chronic hepatitis b virus infection and liver fibrosis in mice. | |
| M=81 | |
| - rna fish to study zygotic genome activation in early mouse embryos. | |
| - detection and characterization of small noncoding rnas in mouse gametes and embryos prior to zygotic genome activation. | |
| M=81 | |
| - chip-seq analysis of genomic binding regions of five major transcription factors highlights a central role for zic2 in the mouse epiblast stem cell gene regulatory network. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - a mouse tissue transcription factor atlas. | |
| - substituting mouse transcription factor pou4f2 with a sea urchin orthologue restores retinal ganglion cell development. | |
| M=81 | |
| - generation of lif-independent induced pluripotent stem cells from canine fetal fibroblasts. | |
| - identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts. | |
| M=81 | |
| - tracking the embryonic stem cell transition from ground state pluripotency. | |
| - jun-mediated changes in cell adhesion contribute to mouse embryonic stem cell exit from ground state pluripotency. | |
| M=81 | |
| - the mouse gene expression database (gxd): 2017 update. | |
| - the mouse gene expression database: new features and how to use them effectively. | |
| M=81 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=81 | |
| - motif oriented high-resolution analysis of chip-seq data reveals the topological order of ctcf and cohesin proteins on dna. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - [viral superantigens]. | |
| - convergent capture of retroviral superantigens by mammalian herpesviruses. | |
| M=81 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - therapeutic genome editing by combined viral and non-viral delivery of crispr system components in vivo. | |
| M=81 | |
| - liver chip-seq analysis in fgf19-treated mice reveals shp as a global transcriptional partner of srebp-2. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - csaw: a bioconductor package for differential binding analysis of chip-seq data using sliding windows. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - crystallization and x-ray diffraction analysis of the hmg domain of the chondrogenesis master regulator sox9 in complex with a chip-seq-identified dna element. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - description of an optimized chip-seq analysis pipeline dedicated to genome wide identification of e4f1 binding sites in primary and transformed mefs. | |
| - de novo chip-seq analysis. | |
| M=81 | |
| - de novo chip-seq analysis. | |
| - papst, a user friendly and powerful java platform for chip-seq peak co-localization analysis and beyond. | |
| M=81 | |
| - single-step generation of conditional knockout mouse embryonic stem cells. | |
| - conditional knockout mouse models of cancer. | |
| M=80 | |
| - crispr libraries and screening. | |
| - analysing the outcome of crispr-aided genome editing in embryos: screening, genotyping and quality control. | |
| M=80 | |
| - crispr libraries and screening. | |
| - compact and highly active next-generation libraries for crispr-mediated gene repression and activation. | |
| M=80 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=80 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - crispr/cas9-mediated insertion of loxp sites in the mouse dock7 gene provides an effective alternative to use of targeted embryonic stem cells. | |
| M=80 | |
| - ribosomal dna copy number loss and sequence variation in cancer. | |
| - concerted copy number variation balances ribosomal dna dosage in human and mouse genomes. | |
| M=80 | |
| - protective efficacy of zika vaccine in ag129 mouse model. | |
| - comparative studies of infectivity, immunogenicity and cross-protective efficacy of live attenuated influenza vaccines containing nucleoprotein from cold-adapted or wild-type influenza virus in a mouse model. | |
| M=80 | |
| - protective efficacy of zika vaccine in ag129 mouse model. | |
| - putative function of hypothetical proteins expressed by clostridium perfringens type a strains and their protective efficacy in mouse model. | |
| M=80 | |
| - somatic genome editing with crispr/cas9 generates and corrects a metabolic disease. | |
| - somatic genome editing goes viral. | |
| M=80 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - generation of a knockout mouse embryonic stem cell line using a paired crispr/cas9 genome engineering tool. | |
| M=80 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - correction of a genetic disease by crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| M=80 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - in vivo and in vitro disease modeling with crispr/cas9. | |
| M=80 | |
| - somatic genome editing goes viral. | |
| - modeling invasive lobular breast carcinoma by crispr/cas9-mediated somatic genome editing of the mammary gland. | |
| M=80 | |
| - somatic genome editing goes viral. | |
| - adenovirus-mediated somatic genome editing of pten by crispr/cas9 in mouse liver in spite of cas9-specific immune responses. | |
| M=80 | |
| - modification of three amino acids in sodium taurocholate cotransporting polypeptide renders mice susceptible to infection with hepatitis d virus in vivo. | |
| - hepatitis d virus infection of mice expressing human sodium taurocholate co-transporting polypeptide. | |
| M=80 | |
| - genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of alzheimer's disease. | |
| - genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism. | |
| M=80 | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=80 | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=80 | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| - efficient crispr/cas9-mediated genome editing in mice by zygote electroporation of nuclease. | |
| M=80 | |
| - mapping the genomic architecture of adaptive traits with interspecific introgressive origin: a coalescent-based approach. | |
| - interspecific introgressive origin of genomic diversity in the house mouse. | |
| M=80 | |
| - characterization of gene expression in mouse embryos at the 1-cell stage. | |
| - characterization of the structure and expression of mouse itpa gene and its related sequences in the mouse genome. | |
| M=80 | |
| - notch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenance. | |
| - a dual role for notch signaling in joint cartilage maintenance and osteoarthritis. | |
| M=80 | |
| - genome-wide analysis of histone acetylation dynamics during mouse embryonic stem cell neural differentiation. | |
| - genome-wide copy number profiling of mouse neural stem cells during differentiation. | |
| M=80 | |
| - transcriptional response in mouse thyroid tissue after 211at administration: effects of absorbed dose, initial dose-rate and time after administration. | |
| - dose-specific transcriptional responses in thyroid tissue in mice after (131)i administration. | |
| M=79 | |
| - efficient generation of genome-modified mice using campylobacter jejuni-derived crispr/cas. | |
| - zygote-mediated generation of genome-modified mice using streptococcus thermophilus 1-derived crispr/cas system. | |
| M=79 | |
| - composition and dosage of a multipartite enhancer cluster control developmental expression of ihh (indian hedgehog). | |
| - developmental expression of paraoxonase 2. | |
| M=79 | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| - [genome editing in mouse with crispr/cas system]. | |
| M=79 | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - complex trait analyses of the collaborative cross: tools and databases. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - using the collaborative cross to study the role of genetic diversity in cancer-related phenotypes. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - influenza h3n2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in cast/eij mice. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - the founder strains of the collaborative cross express a complex combination of advantageous and deleterious traits for male reproduction. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - genome wide identification of sars-cov susceptibility loci using the collaborative cross. | |
| M=79 | |
| - genomes of the mouse collaborative cross. | |
| - splicing landscape of the eight collaborative cross founder strains. | |
| M=79 | |
| - disrupting interactions between β-catenin and activating tcfs reconstitutes ground state pluripotency in mouse embryonic stem cells. | |
| - interactions between pluripotency factors specify cis-regulation in embryonic stem cells. | |
| M=79 | |
| - treatment of dyslipidemia using crispr/cas9 genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - comparative analysis of osteoblast gene expression profiles and runx2 genomic occupancy of mouse and human osteoblasts in vitro. | |
| - comparative transcriptomics in human and mouse. | |
| M=79 | |
| - comparative transcriptomics in human and mouse. | |
| - comprehensive comparative homeobox gene annotation in human and mouse. | |
| M=79 | |
| - comparative transcriptomics in human and mouse. | |
| - comparative analysis of genome maintenance genes in naked mole rat, mouse, and human. | |
| M=79 | |
| - a mouse tissue transcription factor atlas. | |
| - sex- and tissue-specific functions of drosophila doublesex transcription factor target genes. | |
| M=79 | |
| - development of humanized mice in the age of genome editing. | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| M=79 | |
| - dynamic landscape of alternative polyadenylation during retinal development. | |
| - regulation of alternative polyadenylation by nkx2-5 and xrn2 during mouse heart development. | |
| M=79 | |
| - genome-wide analysis of alternative splicing during human heart development. | |
| - genome-wide analysis of dna methylation dynamics during early human development. | |
| M=79 | |
| - amino acid substitutions involved in the adaptation of a novel highly pathogenic h5n2 avian influenza virus in mice. | |
| - adaptive amino acid substitutions enhance the virulence of a novel human h7n9 influenza virus in mice. | |
| M=79 | |
| - functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates bhlhe41. | |
| - functional characterization of rad52 as a lung cancer susceptibility gene in the 12p13.33 locus. | |
| M=79 | |
| - aav-mediated crispr/cas gene editing of retinal cells in vivo. | |
| - correction of a genetic disease by crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| M=79 | |
| - zygote-mediated generation of genome-modified mice using streptococcus thermophilus 1-derived crispr/cas system. | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| M=79 | |
| - crispr/cas9-mediated genome editing of mouse small intestinal organoids. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - sirt7 promotes genome integrity and modulates non-homologous end joining dna repair. | |
| - lrf maintains genome integrity by regulating the non-homologous end joining pathway of dna repair. | |
| M=79 | |
| - the impact of toxoplasma gondii on the mammalian genome. | |
| - affinity-seq detects genome-wide prdm9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage. | |
| M=79 | |
| - role of transient receptor potential ankyrin 1 channels in alzheimer's disease. | |
| - nuclear tau and its potential role in alzheimer's disease. | |
| M=79 | |
| - tox3 regulates neural progenitor identity. | |
| - re1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro. | |
| M=79 | |
| - developmental expression of paraoxonase 2. | |
| - distribution pattern of cytoplasmic organelles, spindle integrity, oxidative stress, octamer-binding transcription factor 4 (oct4) expression and developmental potential of oocytes following multiple superovulation. | |
| M=79 | |
| - developmental expression of paraoxonase 2. | |
| - expression of maternally derived khdc3, nlrp5, ooep and tle6 is associated with oocyte developmental competence in the ovine species. | |
| M=79 | |
| - developmental expression of paraoxonase 2. | |
| - developmental analysis of spliceosomal snrna isoform expression. | |
| M=79 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=79 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - adenovirus-mediated somatic genome editing of pten by crispr/cas9 in mouse liver in spite of cas9-specific immune responses. | |
| M=79 | |
| - editing of mouse and human immunoglobulin genes by crispr-cas9 system. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - improved genome editing efficiency and flexibility using modified oligonucleotides with talen and crispr-cas9 nucleases. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=79 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - pancreatic cancer modeling using retrograde viral vector delivery and in vivo crispr/cas9-mediated somatic genome editing. | |
| M=79 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - adenovirus-mediated somatic genome editing of pten by crispr/cas9 in mouse liver in spite of cas9-specific immune responses. | |
| M=79 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - precision cancer mouse models through genome editing with crispr-cas9. | |
| M=79 | |
| - genetic architecture of early pre-inflammatory stage transcription signatures of autoimmune diabetes in the pancreatic lymph nodes of the nod mouse reveals significant gene enrichment on chromosomes 6 and 7. | |
| - genetic architecture of insulin resistance in the mouse. | |
| M=79 | |
| - genome wide mapping of ubf binding-sites in mouse and human cell lines. | |
| - genome-wide comparison of pu.1 and spi-b binding sites in a mouse b lymphoma cell line. | |
| M=79 | |
| - gnl3 and ska3 are novel prostate cancer metastasis susceptibility genes. | |
| - a systems genetics approach identifies cxcl14, itgax, and lpcat2 as novel aggressive prostate cancer susceptibility genes. | |
| M=79 | |
| - structure of slitrk2-ptpδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion. | |
| - mechanisms of splicing-dependent trans-synaptic adhesion by ptpδ-il1rapl1/il-1racp for synaptic differentiation. | |
| M=79 | |
| - wge: a crispr database for genome engineering. | |
| - mouse genome engineering via crispr-cas9 for study of immune function. | |
| M=79 | |
| - the genetic architecture of the genome-wide transcriptional response to er stress in the mouse. | |
| - genetic architecture of insulin resistance in the mouse. | |
| M=78 | |
| - rtfadb: a database of computationally predicted associations between retrotransposons and transcription factors in the human and mouse genomes. | |
| - the role of retrotransposons in gene family expansions in the human and mouse genomes. | |
| M=78 | |
| - dna polymerase β: a missing link of the base excision repair machinery in mammalian mitochondria. | |
| - [the role of parp2 in dna repair]. | |
| M=78 | |
| - dynamic landscape and regulation of rna editing in mammals. | |
| - global analysis of mouse polyomavirus infection reveals dynamic regulation of viral and host gene expression and promiscuous viral rna editing. | |
| M=78 | |
| - hoxa1 targets signaling pathways during neural differentiation of es cells and mouse embryogenesis. | |
| - dynamic regulation of nanog and stem cell-signaling pathways by hoxa1 during early neuro-ectodermal differentiation of es cells. | |
| M=78 | |
| - genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation. | |
| - genome-wide in vivo screen identifies novel host regulators of metastatic colonization. | |
| M=78 | |
| - whole exome sequencing reveals a functional mutation in the gain domain of the bai2 receptor underlying a forward mutagenesis hyperactivity qtl. | |
| - enu mutagenesis in the mouse. | |
| M=78 | |
| - genome organization drives chromosome fragility. | |
| - spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization. | |
| M=78 | |
| - genetic engineering as a tool for the generation of mouse models to understand disease phenotypes and gene function. | |
| - animal models of rls phenotypes. | |
| M=78 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - aav-mediated crispr/cas gene editing of retinal cells in vivo. | |
| M=78 | |
| - neuroanatomy in mouse models of rett syndrome is related to the severity of mecp2 mutation and behavioral phenotypes. | |
| - animal models of rls phenotypes. | |
| M=78 | |
| - genome-wide mapping of in vivo erα-binding sites in male mouse efferent ductules. | |
| - genome wide mapping of ubf binding-sites in mouse and human cell lines. | |
| M=78 | |
| - targeted deletion of an entire chromosome using crispr/cas9. | |
| - analysis of noncanonical calcium-dependent protein kinases in toxoplasma gondii by targeted gene deletion using crispr/cas9. | |
| M=78 | |
| - low-expression of tmem100 is associated with poor prognosis in non-small-cell lung cancer. | |
| - high expression of p62 protein is associated with poor prognosis and aggressive phenotypes in endometrial cancer. | |
| M=78 | |
| - dynamic regulation of small rnaome during the early stage of cardiac differentiation from pluripotent embryonic stem cells. | |
| - lack of rybp in mouse embryonic stem cells impairs cardiac differentiation. | |
| M=78 | |
| - mouse rif1 is a regulatory subunit of protein phosphatase 1 (pp1). | |
| - hepatic protein phosphatase 1 regulatory subunit 3b (ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis. | |
| M=78 | |
| - a mouse tissue transcription factor atlas. | |
| - the transcription factor nfatc2 regulates β-cell proliferation and genes associated with type 2 diabetes in mouse and human islets. | |
| M=78 | |
| - a mouse tissue transcription factor atlas. | |
| - protein delivery of an artificial transcription factor restores widespread ube3a expression in an angelman syndrome mouse brain. | |
| M=78 | |
| - a mouse tissue transcription factor atlas. | |
| - compound hierarchical correlated beta mixture with an application to cluster mouse transcription factor dna binding data. | |
| M=78 | |
| - a mouse tissue transcription factor atlas. | |
| - re1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro. | |
| M=78 | |
| - runx3 in immunity, inflammation and cancer. | |
| - gene expression architecture of mouse dorsal and tail skin reveals functional differences in inflammation and cancer. | |
| M=78 | |
| - runx3 in immunity, inflammation and cancer. | |
| - chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer. | |
| M=78 | |
| - expanding the genetic code of mus musculus. | |
| - genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (mus musculus domesticus). | |
| M=78 | |
| - muscle-specific crispr/cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for duchenne muscular dystrophy. | |
| - in vivo genome editing improves muscle function in a mouse model of duchenne muscular dystrophy. | |
| M=78 | |
| - sex difference in egfr pathways in mouse kidney-potential impact on the immune system. | |
| - dcir in the "osteo-immune" system. | |
| real 14m25,818s | |
| user 14m21,128s | |
| sys 0m4,580s | |
| michal@e6540:~/workspace/liclipse/plagiat$ |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| michal@e6540:~/workspace/liclipse/plagiat$ | |
| michal@e6540:~/workspace/liclipse/plagiat$ time python ./plagiat.py --lowercase --limitoutput 200 --limitinput 6000 --method ComparisonTokenSet && time python ./plagiat.py --lowercase --limitoutput 200 --limitinput 6000 --method ComparisonTokenSort | |
| ===== | |
| data = pubmed_result.csv | |
| limitinput = 6000 | |
| limitoutput = 200 | |
| method = ComparisonTokenSet | |
| lowercase = True | |
| ===== | |
| max number of combinations to check: 17997000 | |
| Compared! |████████████████████████████████████████████████████████████████████████████████████████████████████| 100.0% | |
| M=100 | |
| - pathogenesis of lafora disease: transition of soluble glycogen to insoluble polyglucosan. | |
| - lafora disease. | |
| M=100 | |
| - cloning mice. | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| M=100 | |
| - cloning mice. | |
| - from cloning neural development genes to functional studies in mice, 30 years of advancements. | |
| M=100 | |
| - corrigendum: asymmetric parental genome engineering by cas9 during mouse meiotic exit. | |
| - asymmetric parental genome engineering by cas9 during mouse meiotic exit. | |
| M=100 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - correction of a genetic disease by crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| M=100 | |
| - erratum: genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer. | |
| - genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer. | |
| M=100 | |
| - abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in lafora disease. | |
| - lafora disease. | |
| M=100 | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| - cloning-free crispr. | |
| M=100 | |
| - the evolutionary capacitor hsp90 buffers the regulatory effects of mammalian endogenous retroviruses. | |
| - mammalian endogenous retroviruses. | |
| M=100 | |
| - liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency. | |
| - arginase-1 deficiency. | |
| M=100 | |
| - pronuclear injection-based targeted transgenesis. | |
| - one-step generation of multiple transgenic mouse lines using an improved pronuclear injection-based targeted transgenesis (i-pitt). | |
| M=100 | |
| - erratum to: trans effects of chromosome aneuploidies on dna methylation patterns in human down syndrome and mouse models. | |
| - trans effects of chromosome aneuploidies on dna methylation patterns in human down syndrome and mouse models. | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - erratum to: cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. | |
| - cytoplasm-predominant pten associates with increased region-specific brain tyrosine hydroxylase and dopamine d2 receptors in mouse model with autistic traits. | |
| M=100 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=100 | |
| - arginase-1 deficiency. | |
| - strategies to rescue the consequences of inducible arginase-1 deficiency in mice. | |
| M=100 | |
| - corrigendum: extensive microrna-mediated crosstalk between lncrnas and mrnas in mouse embryonic stem cells. | |
| - extensive microrna-mediated crosstalk between lncrnas and mrnas in mouse embryonic stem cells. | |
| M=100 | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| - complete mitochondrial genome of the gray mouse lemur, microcebus murinus (primates, cheirogaleidae). | |
| M=100 | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| - sequencing and analysis of complete mitochondrial genome of apodemus draco (rodentia: arvicolinae). | |
| M=100 | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=100 | |
| - corrigendum to "disruption of the potassium channel regulatory subunit kcne2 causes iron-deficient anemia" [experimental hematology, vol. 42, issue 12, p1053-1058.e1]. | |
| - disruption of the potassium channel regulatory subunit kcne2 causes iron-deficient anemia. | |
| M=99 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - mouse genome editing using the crispr/cas system. | |
| M=98 | |
| - activity-dependent dynamics of the transcription factor of camp-response element binding protein in cortical neurons revealed by single-molecule imaging. | |
| - activity-dependent dynamics of the transcription factor creb in cortical neurons revealed by single-molecule imaging. | |
| M=97 | |
| - erratum to: deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| - deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the dna methylation landscape. | |
| M=96 | |
| - runx3 in immunity, inflammation and cancer. | |
| - runx3 at the interface of immunity, inflammation and cancer. | |
| M=96 | |
| - single-cell transcriptome and epigenomic reprogramming of cardiomyocyte-derived cardiac progenitor cells. | |
| - epigenomic reprogramming of adult cardiomyocyte-derived cardiac progenitor cells. | |
| M=96 | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| - mouse genome editing using the crispr/cas system. | |
| M=95 | |
| - multicolor spectral analyses of mitotic and meiotic mouse chromosomes involved in multiple robertsonian translocations. ii. the nmri/cd and cd/ta hybrid strains. | |
| - multicolor spectral analyses of mitotic and meiotic mouse chromosomes involved in multiple robertsonian translocations. i. the cd/cremona hybrid strain. | |
| M=93 | |
| - crispr libraries and screening. | |
| - coralina: a universal method for the generation of grna libraries for crispr-based screening. | |
| M=93 | |
| - identification and functional analysis of long non-coding rnas in human and mouse early embryos based on single-cell transcriptome data. | |
| - identification and analysis of mouse non-coding rna using transcriptome data. | |
| M=93 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| M=92 | |
| - single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy. | |
| - postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy. | |
| M=92 | |
| - genome editing in mouse zygotes and embryonic stem cells by introducing sgrna/cas9 expressing plasmids. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=92 | |
| - a mouse model of hereditary coproporphyria identified in an enu mutagenesis screen. | |
| - enu mutagenesis in the mouse. | |
| M=92 | |
| - somatic genome editing goes viral. | |
| - pancreatic cancer modeling using retrograde viral vector delivery and in vivo crispr/cas9-mediated somatic genome editing. | |
| M=92 | |
| - toll-like receptors: potential targets for lupus treatment. | |
| - toll-like receptors in systemic lupus erythematosus: potential for personalized treatment. | |
| M=92 | |
| - expression and localization of nlrp4g in mouse preimplantation embryo. | |
| - localization and expression of histone h2a variants during mouse oogenesis and preimplantation embryo development. | |
| M=91 | |
| - circadian control of global transcription. | |
| - chip-seq and rna-seq methods to study circadian control of transcription in mammals. | |
| M=90 | |
| - continuous blockade of cxcr4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells. | |
| - ex vivo expansion of hematopoietic stem cells. | |
| M=90 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - mouse genome editing using the crispr/cas system. | |
| M=90 | |
| - divergence patterns of genic copy number variation in natural populations of the house mouse (mus musculus domesticus) reveal three conserved genes with major population-specific expansions. | |
| - genomic copy number variation in mus musculus. | |
| M=89 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome database 2016. | |
| M=89 | |
| - role of the dna repair glycosylase ogg1 in the activation of murine splenocytes. | |
| - [the role of parp2 in dna repair]. | |
| M=89 | |
| - genome editing in mouse and rat by electroporation. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=89 | |
| - genome editing in mouse and rat by electroporation. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=89 | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=89 | |
| - cellular reprogramming, genome editing, and alternative crispr cas9 technologies for precise gene therapy of duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=89 | |
| - male infertility is responsible for nearly half of the extinction observed in the mouse collaborative cross. | |
| - genomes of the mouse collaborative cross. | |
| M=89 | |
| - muscle-specific crispr/cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=89 | |
| - mouse genome database (mgd)-2017: community knowledge resource for the laboratory mouse. | |
| - mouse genome database 2016. | |
| M=89 | |
| - the potential role of 8-oxoguanine dna glycosylase-driven dna base excision repair in exercise-induced asthma. | |
| - [the role of parp2 in dna repair]. | |
| M=89 | |
| - exploring novel candidate genes from the mouse genome informatics database: potential implications for avian migration research. | |
| - mouse genome database 2016. | |
| M=89 | |
| - mouse genome database 2016. | |
| - dbsuper: a database of super-enhancers in mouse and human genome. | |
| M=89 | |
| - mouse genome database 2016. | |
| - orthology for comparative genomics in the mouse genome database. | |
| M=89 | |
| - mouse genome database 2016. | |
| - mouse genome database: from sequence to phenotypes and disease models. | |
| M=89 | |
| - mouse genome database 2016. | |
| - the mouse genome database (mgd): facilitating mouse as a model for human biology and disease. | |
| M=89 | |
| - single-step generation of conditional knockout mouse embryonic stem cells. | |
| - rapid knockout and reporter mouse line generation and breeding colony establishment using eucomm conditional-ready embryonic stem cells: a case study. | |
| M=89 | |
| - a central role of trax in the atm-mediated dna repair. | |
| - [the role of parp2 in dna repair]. | |
| M=88 | |
| - combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models. | |
| - development of humanized mice in the age of genome editing. | |
| M=88 | |
| - an efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | |
| - generation and application of mouse-rat allodiploid embryonic stem cells. | |
| M=88 | |
| - genome editing in mouse and rat by electroporation. | |
| - highly efficient mouse genome editing by crispr ribonucleoprotein electroporation of zygotes. | |
| M=88 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - [genome editing in mouse with crispr/cas system]. | |
| M=88 | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| - mouse genome editing using the crispr/cas system. | |
| M=87 | |
| - replication study: melanoma genome sequencing reveals frequent prex2 mutations. | |
| - registered report: melanoma genome sequencing reveals frequent prex2 mutations. | |
| M=87 | |
| - generating mouse models using crispr-cas9-mediated genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=87 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=87 | |
| - genome editing in mice using tale nucleases. | |
| - genome editing in mouse spermatogonial stem/progenitor cells using engineered nucleases. | |
| M=86 | |
| - hotspots of de novo point mutations in induced pluripotent stem cells. | |
| - the number of point mutations in induced pluripotent stem cells and nuclear transfer embryonic stem cells depends on the method and somatic cell type used for their generation. | |
| M=86 | |
| - data on the effect of in utero exposure to polycyclic aromatic hydrocarbons on genome-wide patterns of dna methylation in lung tissues. | |
| - dna methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons. | |
| M=86 | |
| - crispr/cas9 - mediated precise targeted integration in vivo using a double cut donor with short homology arms. | |
| - homology-mediated end joining-based targeted integration using crispr/cas9. | |
| M=86 | |
| - effective biomedical document classification for identifying publications relevant to the mouse gene expression database (gxd). | |
| - the mouse gene expression database (gxd): 2017 update. | |
| M=86 | |
| - initial characterization of behavior and ketamine response in a mouse knockout of the post-synaptic effector gene anks1b. | |
| - the eif2a knockout mouse. | |
| M=86 | |
| - single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types. | |
| - evolution of the unspliced transcriptome. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - exome-wide single-base substitutions in tissues and derived cell lines of the constitutive fhit knockout mouse. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - beyond knockouts: the international knockout mouse consortium delivers modular and evolving tools for investigating mammalian genes. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens. | |
| M=86 | |
| - the eif2a knockout mouse. | |
| - utilising the resources of the international knockout mouse consortium: the australian experience. | |
| M=86 | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=86 | |
| - gene therapies that restore dystrophin expression for the treatment of duchenne muscular dystrophy. | |
| - duchenne muscular dystrophy: crispr/cas9 treatment. | |
| M=86 | |
| - generation and application of mammalian haploid embryonic stem cells. | |
| - generation and application of mouse-rat allodiploid embryonic stem cells. | |
| M=86 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - editing the mouse genome using the crispr-cas9 system. | |
| M=86 | |
| - comparative genomics: one for all. | |
| - orthology for comparative genomics in the mouse genome database. | |
| M=86 | |
| - comparative genomics: one for all. | |
| - application of comparative transcriptional genomics to identify molecular targets for pediatric ibd. | |
| M=86 | |
| - excavating the genome: large-scale mutagenesis screening for the discovery of new mouse models. | |
| - enu mutagenesis in the mouse. | |
| M=86 | |
| - enu mutagenesis in the mouse. | |
| - mouse enu mutagenesis to understand immunity to infection: methods, selected examples, and perspectives. | |
| M=86 | |
| - molecular and cellular regulation of skeletal myogenesis. | |
| - transcriptional regulation of important cellular processes in skeletal myogenesis through interferon-γ. | |
| M=85 | |
| - landscape of dna methylation on the marsupial x. | |
| - influence of the prader-willi syndrome imprinting center on the dna methylation landscape in the mouse brain. | |
| M=85 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome database (mgd)-2017: community knowledge resource for the laboratory mouse. | |
| M=85 | |
| - an efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | |
| - generation and application of mammalian haploid embryonic stem cells. | |
| M=85 | |
| - functional validation of atf4 and gadd34 in neuro2a cells by crispr/cas9-mediated genome editing. | |
| - functional validation of tensin2 sh2-ptb domain by crispr/cas9-mediated genome editing. | |
| M=85 | |
| - generation of knock-in mouse by genome editing. | |
| - crispr/cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene. | |
| M=85 | |
| - generation of knock-in mouse by genome editing. | |
| - generation of an oocyte-specific cas9 transgenic mouse for genome editing. | |
| M=85 | |
| - crispr/cas9-mediated gene manipulation to create single-amino-acid-substituted and floxed mice with a cloning-free method. | |
| - self-cloning crispr. | |
| M=85 | |
| - self-cloning crispr. | |
| - in vivo blunt-end cloning through crispr/cas9-facilitated non-homologous end-joining. | |
| M=85 | |
| - self-cloning crispr. | |
| - cloning-free crispr. | |
| M=85 | |
| - the potential role of 8-oxoguanine dna glycosylase-driven dna base excision repair in exercise-induced asthma. | |
| - the role of 8-oxoguanine dna glycosylase-1 in inflammation. | |
| M=85 | |
| - the role of mdm2 amplification and overexpression in tumorigenesis. | |
| - gene amplification-associated overexpression of the rna editing enzyme adar1 enhances human lung tumorigenesis. | |
| M=85 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=85 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - erratum: electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=85 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - electroporation enables the efficient mrna delivery into the mouse zygotes and facilitates crispr/cas9-based genome editing. | |
| M=85 | |
| - in vivo blunt-end cloning through crispr/cas9-facilitated non-homologous end-joining. | |
| - cloning-free crispr. | |
| M=85 | |
| - assessment of microrna expression in mouse epididymal epithelial cells and spermatozoa by next generation sequencing. | |
| - next generation sequencing analysis reveals segmental patterns of microrna expression in mouse epididymal epithelial cells. | |
| M=85 | |
| - transcriptional response in mouse thyroid tissue after 211at administration: effects of absorbed dose, initial dose-rate and time after administration. | |
| - transcriptional response in normal mouse tissues after i.v. (211)at administration - response related to absorbed dose, dose rate, and time. | |
| M=85 | |
| - syntaxin-binding protein stxbp5 inhibits endothelial exocytosis and promotes platelet secretion. | |
| - platelet secretion and hemostasis require syntaxin-binding protein stxbp5. | |
| M=84 | |
| - amino acid substitutions associated with avian h5n6 influenza a virus adaptation to mice. | |
| - amino acid substitutions involved in the adaptation of a novel highly pathogenic h5n2 avian influenza virus in mice. | |
| M=84 | |
| - genome editing in mouse and rat by electroporation. | |
| - efficient crispr/cas9-mediated genome editing in mice by zygote electroporation of nuclease. | |
| M=84 | |
| - p53 and tap63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes. | |
| - the atm signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. | |
| M=84 | |
| - genomes of the mouse collaborative cross. | |
| - collaborative cross and diversity outbred data resources in the mouse phenome database. | |
| M=84 | |
| - genomes of the mouse collaborative cross. | |
| - informatics resources for the collaborative cross and related mouse populations. | |
| M=84 | |
| - complete genome sequence of acinetobacter sp. strain ncu2d-2 isolated from a mouse. | |
| - complete genome sequence of turicibacter sp. strain h121, isolated from the feces of a contaminated germ-free mouse. | |
| M=84 | |
| - genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. | |
| - the genetic architecture of nafld among inbred strains of mice. | |
| M=84 | |
| - pancreatic cancer modeling using retrograde viral vector delivery and in vivo crispr/cas9-mediated somatic genome editing. | |
| - crispr-cas9 knockin mice for genome editing and cancer modeling. | |
| M=83 | |
| - pd-l1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - mouse genome database (mgd)-2018: knowledgebase for the laboratory mouse. | |
| - mouse genome informatics (mgi) resource: genetic, genomic, and biological knowledgebase for the laboratory mouse. | |
| M=83 | |
| - human t-cell leukemia virus type 1 infection and adult t-cell leukemia. | |
| - effects of expressing human t-cell leukemia virus type 1 (htlv-i) oncoprotein tax on dok1, dok2 and dok3 gene expression in mice. | |
| M=83 | |
| - human t-cell leukemia virus type 1 infection and adult t-cell leukemia. | |
| - human t-cell leukemia virus type 1 (htlv-1) tax requires cadm1/tslc1 for inactivation of the nf-κb inhibitor a20 and constitutive nf-κb signaling. | |
| M=83 | |
| - shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the united states. | |
| - zinc and diabetes. | |
| M=83 | |
| - a five-repeat micro-dystrophin gene ameliorated dystrophic phenotype in the severe dba/2j-mdx model of duchenne muscular dystrophy. | |
| - jagged 1 rescues the duchenne muscular dystrophy phenotype. | |
| M=83 | |
| - engineered epidermal progenitor cells can correct diet-induced obesity and diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - tex19.1 promotes spo11-dependent meiotic recombination in mouse spermatocytes. | |
| - the atm signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. | |
| M=83 | |
| - identification and characterization of a foxa2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls gckr expression in liver cells. | |
| - zinc and diabetes. | |
| M=83 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - crispr/cas9-mediated genome editing corrects dystrophin mutation in skeletal muscle stem cells in a mouse model of muscle dystrophy. | |
| M=83 | |
| - crispr-cas9-mediated gene editing in mouse spermatogonial stem cells. | |
| - genome editing in mouse spermatogonial stem cell lines using talen and double-nicking crispr/cas9. | |
| M=83 | |
| - expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion. | |
| - zinc and diabetes. | |
| M=83 | |
| - targeted dna methylation in pericentromeres with genome editing-based artificial dna methyltransferase. | |
| - editing dna methylation in the mammalian genome. | |
| M=83 | |
| - using hescs to probe the interaction of the diabetes-associated genes cdkal1 and mt1e. | |
| - zinc and diabetes. | |
| M=83 | |
| - dna modifications and alzheimer's disease. | |
| - modifiers and readers of dna modifications and their impact on genome structure, expression, and stability in disease. | |
| M=83 | |
| - the zinc finger e-box-binding homeobox 1 (zeb1) promotes the conversion of mouse fibroblasts into functional neurons. | |
| - chemical conversion of mouse fibroblasts into functional dopaminergic neurons. | |
| M=83 | |
| - genetic and small molecule disruption of the aid/rad51 axis similarly protects nonobese diabetic mice from type 1 diabetes through expansion of regulatory b lymphocytes. | |
| - zinc and diabetes. | |
| M=83 | |
| - long-term alterations to dna methylation as a biomarker of prenatal alcohol exposure: from mouse models to human children with fetal alcohol spectrum disorders. | |
| - associative dna methylation changes in children with prenatal alcohol exposure. | |
| M=83 | |
| - genetics of obesity: can an old dog teach us new tricks? | |
| - systems genetics of obesity. | |
| M=83 | |
| - the transcription factor nfatc2 regulates β-cell proliferation and genes associated with type 2 diabetes in mouse and human islets. | |
| - zinc and diabetes. | |
| M=83 | |
| - systems genetics of obesity. | |
| - visualization of results from systems genetics studies in chromosomal context. | |
| M=83 | |
| - systems genetics of obesity. | |
| - a suite of tools for biologists that improve accessibility and visualization of large systems genetics datasets: applications to the hybrid mouse diversity panel. | |
| M=83 | |
| - systems genetics of obesity. | |
| - defining the influence of germline variation on metastasis using systems genetics approaches. | |
| M=83 | |
| - systems genetics of obesity. | |
| - the hybrid mouse diversity panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. | |
| M=83 | |
| - systems genetics of obesity. | |
| - genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. | |
| M=83 | |
| - systems genetics of obesity. | |
| - systems genetics of intravenous cocaine self-administration in the bxd recombinant inbred mouse panel. | |
| M=83 | |
| - systems genetics of obesity. | |
| - application of quantitative metabolomics in systems genetics in rodent models of complex phenotypes. | |
| M=83 | |
| - systems genetics of obesity. | |
| - a systems genetics study of swine illustrates mechanisms underlying human phenotypic traits. | |
| M=83 | |
| - systems genetics of obesity. | |
| - systems genetics identifies sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus. | |
| M=83 | |
| - emerging roles of glis3 in neonatal diabetes, type 1 and type 2 diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - differential gene dosage effects of diabetes-associated gene glis3 in pancreatic β cell differentiation and function. | |
| - zinc and diabetes. | |
| M=83 | |
| - transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms. | |
| - enu mutagenesis in the mouse. | |
| M=83 | |
| - inhibition of dna methyltransferase 1 increases nuclear receptor subfamily 4 group a member 1 expression and decreases blood glucose in type 2 diabetes. | |
| - zinc and diabetes. | |
| M=83 | |
| - microinjection-based generation of mutant mice with a double mutation and a 0.5 mb deletion in their genome by the crispr/cas9 system. | |
| - generation of site-specific mutant mice using the crispr/cas9 system. | |
| M=83 | |
| - an integrative study identifies kcnc2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the korean population. | |
| - zinc and diabetes. | |
| M=83 | |
| - structural organization of the inactive x chromosome in the mouse. | |
| - bipartite structure of the inactive mouse x chromosome. | |
| M=83 | |
| - zinc and diabetes. | |
| - serotonin as a new therapeutic target for diabetes mellitus and obesity. | |
| M=83 | |
| - zinc and diabetes. | |
| - unexpected partial correction of metabolic and behavioral phenotypes of alzheimer's app/psen1 mice by gene targeting of diabetes/alzheimer's-related sorcs1. | |
| M=83 | |
| - zinc and diabetes. | |
| - type 1 diabetes genetic susceptibility and dendritic cell function: potential targets for treatment. | |
| M=83 | |
| - zinc and diabetes. | |
| - genetic association of long-chain acyl-coa synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis. | |
| M=83 | |
| - zinc and diabetes. | |
| - a20 inhibits β-cell apoptosis by multiple mechanisms and predicts residual β-cell function in type 1 diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - genetic architecture of early pre-inflammatory stage transcription signatures of autoimmune diabetes in the pancreatic lymph nodes of the nod mouse reveals significant gene enrichment on chromosomes 6 and 7. | |
| M=83 | |
| - zinc and diabetes. | |
| - ptpn22 and cd2 variations are associated with altered protein expression and susceptibility to type 1 diabetes in nonobese diabetic mice. | |
| M=83 | |
| - zinc and diabetes. | |
| - phenotypic characterization of mice carrying homozygous deletion of klf11, a gene in which mutations cause human neonatal and mody vii diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - ptprd silencing by dna hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes. | |
| M=83 | |
| - zinc and diabetes. | |
| - the pathogenic role of persistent milk signaling in mtorc1- and milk-microrna-driven type 2 diabetes mellitus. | |
| M=83 | |
| - zinc and diabetes. | |
| - shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities. | |
| M=83 | |
| - sequence diversity, intersubgroup relationships, and origins of the mouse leukemia gammaretroviruses of laboratory and wild mice. | |
| - origins of the endogenous and infectious laboratory mouse gammaretroviruses. | |
| M=83 | |
| - rag2 and xlf/cernunnos interplay reveals a novel role for the rag complex in dna repair. | |
| - [the role of parp2 in dna repair]. | |
| M=83 | |
| - nuclear localization of the dna repair scaffold xrcc1: uncovering the functional role of a bipartite nls. | |
| - [the role of parp2 in dna repair]. | |
| M=83 | |
| - genomic copy number variation in mus musculus. | |
| - connecting anxiety and genomic copy number variation: a genome-wide analysis in cd-1 mice. | |
| M=83 | |
| - enu mutagenesis in the mouse. | |
| - simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells. | |
| M=83 | |
| - enu mutagenesis in the mouse. | |
| - piggybac transposon-based insertional mutagenesis in mouse haploid embryonic stem cells. | |
| M=82 | |
| - genome-wide discovery of long intergenic noncoding rnas and their epigenetic signatures in the rat. | |
| - mutations in the noncoding genome. | |
| M=82 | |
| - replication stress in hematopoietic stem cells in mouse and man. | |
| - a short g1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. | |
| M=82 | |
| - complete genome sequence of a strain of bifidobacterium pseudolongum isolated from mouse feces and associated with improved organ transplant outcome. | |
| - complete genome sequence of acinetobacter sp. strain ncu2d-2 isolated from a mouse. | |
| M=82 | |
| - highly variable genomic landscape of endogenous retroviruses in the c57bl/6j inbred strain, depending on individual mouse, gender, organ type, and organ location. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - a modifier of huntington's disease onset at the mlh1 locus. | |
| - chromosome substitution strain assessment of a huntington's disease modifier locus. | |
| M=82 | |
| - a14 comprehensive characterisation and evolutionary analysis of endogenous retroviruses in the mouse genome. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - functional validation of atf4 and gadd34 in neuro2a cells by crispr/cas9-mediated genome editing. | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| M=82 | |
| - the hope and hype of crispr-cas9 genome editing: a review. | |
| - the development of a viral mediated crispr/cas9 system with doxycycline dependent grna expression for inducible in vitro and in vivo genome editing. | |
| M=82 | |
| - detection of rna polymerase ii in mouse embryos during zygotic genome activation using immunocytochemistry. | |
| - rna fish to study zygotic genome activation in early mouse embryos. | |
| M=82 | |
| - identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts. | |
| - generation of integration-free induced neural stem cells from mouse fibroblasts. | |
| M=82 | |
| - comparative dynamics of 5-methylcytosine reprogramming and tet family expression during preimplantation mammalian development in mouse and sheep. | |
| - maternal sin3a regulates reprogramming of gene expression during mouse preimplantation development. | |
| M=82 | |
| - targeting of heat shock protein hspa6 (hsp70b') to the periphery of nuclear speckles is disrupted by a transcription inhibitor following thermal stress in human neuronal cells. | |
| - localization of heat shock protein hspa6 (hsp70b') to sites of transcription in cultured differentiated human neuronal cells following thermal stress. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - crispr/cas9 mediated genome editing in es cells and its application for chimeric analysis in mice. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - crispr/cas9-mediated insertion of loxp sites in the mouse dock7 gene provides an effective alternative to use of targeted embryonic stem cells. | |
| M=82 | |
| - crispr/cas9 genome editing in embryonic stem cells. | |
| - generating crispr/cas9 mediated monoallelic deletions to study enhancer function in mouse embryonic stem cells. | |
| M=82 | |
| - integration and fixation preferences of human and mouse endogenous retroviruses uncovered with functional data analysis. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - [genome editing in mouse with crispr/cas system]. | |
| - precision cancer mouse models through genome editing with crispr-cas9. | |
| M=82 | |
| - generating mouse models using crispr-cas9-mediated genome editing. | |
| - advantages of using the crispr/cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. | |
| M=82 | |
| - improved genome editing efficiency and flexibility using modified oligonucleotides with talen and crispr-cas9 nucleases. | |
| - genome editing in mice using tale nucleases. | |
| M=82 | |
| - editing the mouse genome using the crispr-cas9 system. | |
| - insertion of sequences at the original provirus integration site of mouse rosa26 locus using the crispr/cas9 system. | |
| M=82 | |
| - generation of genetically modified mice using the crispr-cas9 genome-editing system. | |
| - generation of site-specific mutant mice using the crispr/cas9 system. | |
| M=82 | |
| - the role of human endogenous retroviruses in brain development and function. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - genomic landscapes of endogenous retroviruses unveil intricate genetics of conventional and genetically-engineered laboratory mouse strains. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - trim33 binds and silences a class of young endogenous retroviruses in the mouse testis; a novel component of the arms race between retrotransposons and the host genome. | |
| - mammalian endogenous retroviruses. | |
| M=82 | |
| - towards autotrophic tissue engineering: photosynthetic gene therapy for regeneration. | |
| - photosynthetic biomaterials: a pathway towards autotrophic tissue engineering. | |
| M=82 | |
| - mutations in the noncoding genome. | |
| - assessing recent selection and functionality at long noncoding rna loci in the mouse genome. | |
| M=82 | |
| - mutations in the noncoding genome. | |
| - generation of site-specific mutations in the rat genome via crispr/cas9. | |
| M=82 | |
| - comprehensive dna methylation analysis of retrotransposons in male germ cells. | |
| - locus-specific dna methylation analysis of retrotransposons in es, somatic and cancer cells using high-throughput targeted repeat element bisulfite sequencing. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the histone methyltransferase setdb1 represses endogenous and exogenous retroviruses in b lymphocytes. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the krab zinc finger protein zfp809 is required to initiate epigenetic silencing of endogenous retroviruses. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the decline of human endogenous retroviruses: extinction and survival. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - setdb1 is required for germline development and silencing of h3k9me3-marked endogenous retroviruses in primordial germ cells. | |
| M=82 | |
| - mammalian endogenous retroviruses. | |
| - the distribution of insertionally polymorphic endogenous retroviruses in breast cancer patients and cancer-free controls. | |
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment