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@neksa
Created June 16, 2020 16:43
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# from https://www.mdanderson.org/documents/Labs/Wood-Laboratory/human-dna-repair-genes.html
BER:
- UNG
- SMUG1
- MBD4
- TDG
- OGG1
- MUTYH
- MYH
- NTHL1NTH1
- MPG
- NEIL1
- NEIL2
- NEIL3
Other-BER:
- APEX1
- APE1
- APEX2
- LIG3
- XRCC1
- PNKP
- APLF
- C2ORF13
PARP:
- PARP1
- ADPRT
- PARP2
- ADPRTL2
- PARP3
- ADPRTL3
Direct-reversal:
- MGMT
- ALKBH2
- ABH2
- ALKBH3
- DEPC1
Topo-crosslinks:
- TDP1
- TDP2
- TTRAP
MMR:
- MSH2
- MSH3
- MSH6
- MLH1
- PMS2
- MSH4
- MSH5
- MLH3
- PMS1
- PMS2P3
- PMS2L3
NER:
- XPC
- RAD23B
- CETN2
- RAD23A
- XPA
- DDB1
- DDB2
- XPE
- RPA1
- RPA2
- RPA3
- TFIIH
- ERCC3
- XPB
- ERCC2
- XPD
- GTF2H1
- GTF2H2
- GTF2H3
- GTF2H4
- GTF2H5
- TTDA
- CDK7
- CCNH
- MNAT1
- ERCC5
- XPG
- ERCC1
- ERCC4
- XPF
- LIG1
NER-related:
- ERCC8
- CSA
- ERCC6
- CSB
- UVSSA
- KIAA1530
- XAB2
- HCNP
- MMS19
HR:
- RAD51
- RAD51B
- RAD51D
- DMC1
- XRCC2
- XRCC3
- RAD52
- RAD54L
- RAD54B
- BRCA1
- SEM1
- SHFM1
- DSS1
- RAD50
- MRE11A
- NBN
- NBS1
- RBBP8
- CtIP
- MUS81
- EME1
- MMS4L
- EME2
- SLX1A
- GIYD1
- SLX1B
- GIYD2
- GEN1
Fanconi-anemia:
- FANCA
- FANCB
- FANCC
- BRCA2
- FANCD1
- FANCD2
- FANCE
- FANCF
- FANCG
- XRCC9
- FANCI
- KIAA1794
- BRIP1
- FANCJ
- FANCL
- FANCM
- PALB2
- FANCN
- RAD51C
- FANCO
- SLX4
- BTBD12
- FANCP
- FAAP20
- C1orf86
- FAAP24
- C19orf40
NH-EJ:
- XRCC6
- Ku70
- XRCC5
- Ku80
- PRKDC
- LIG4
- XRCC4
- DCLRE1C
- Artemis
- NHEJ1
- XLF
Nucleotide-pools:
- NUDT1
- MTH1
- DUT
- RRM2B
- p53R2
DNA-polymerases:
- POLB
- POLG
- POLD1
- POLE
- PCNA
- REV3L
- POLZ
- MAD2L2
- REV7
- REV1
- REV1L
- POLH
- POLI
- RAD30B
- POLQ
- POLK
- DINB1
- POLL
- POLM
- POLN
- POL4P
Editing-nucleases:
- FEN1
- FAN1
- MTMR15
- TREX1
- TREX2
- EXO1
- HEX1
- APTX
- SPO11
- ENDOV
Ubiquitination:
- UBE2A
- RAD6A
- UBE2B
- RAD6B
- RAD18
- SHPRH
- HLTF
- SMARCA3
- RNF168
- SPRTN
- c1orf124
- RNF8
- RNF4
- UBE2V2
- MMS2
- UBE2N
- UBC13
Chromatin:
- H2AX
- H2AFX
- CHAF1A
- CAF1
- SETMAR
- METNASE
Damaging-agents-Sens:
- BLM
- WRN
- RECQL4
- ATM
- MPLKIP
- TTDN1
- C7orf11
Other-DDR:
- DCLRE1A
- SNM1
- DCLRE1B
- SNM1B
- RPA4
- PRPF19
- PSO4
- RECQL
- RECQ1
- RECQL5
- HELQ
- HEL308
- RDM1
- RAD52B
- NABP2
- OBFC2B
- SSB1
Other-Damage-Response:
- ATR
- ATRIP
- MDC1
- RAD1
- RAD9A
- HUS1
- RAD17
- RAD24
- CHEK1
- CHEK2
- TP53
- TP53BP1
- 53BP1
- RIF1
- TOPBP1
- CLK2
- PER1
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