gistfile1.rb

require 'sequel'

class Configuration
  # ... logic for finding configuration strings for different environments / applications.

  def self.datastore
    @datastore ||= Sequel.connect(connection_uri)
  end
end

class Event < Sequel::Model(Configuration.datastore[:events])
  # ...
end

Event.first # => nil

# sudo /etc/init.d/mysql restart

Event.first # => Mysql::Error