AI and Machine Learning
- Generative AI for game development: @GoogleDeepMind introduced Genie, a new AI model that can create playable 2D platformer worlds from a single image prompt, sketch, or text description, with potential to help train AI agents.
- AI-designed drug candidates: @InSilicoMeds will showcase 5 molecules at @AACR, including ISM9182A, a novel, potent, selective, AI-designed HPK1 inhibitor positioned as a promising immuno-oncology therapeutic.
- AI for enzyme engineering: @Ginkgo is partnering with Prozomix to leverage Ginkgo's industry-leading AI/ML models along with Prozomix's enzyme libraries to get enzymes into as many API routes as possible and help partners meet COGs savings and sustainability goals.
Biotechnology and Synthetic Biology
- Scaling biomanufacturing: @johncumbers invites industrial and synbio leaders to discuss practically reaching scale for biomanufacturing on a timeline that benefits business and the planet at #SynBioBeta2024.
- Synthetic gene circuits: @NikoMcCarty shares that @ElowitzLab made one of the first synthetic gene circuits, the repressilator, originally called the "oscillon", helping establish the field of synthetic biology.
- Generative protein design: @johncumbers highlights how the promise of generative protein design extends beyond scientific advancements into personalized medicine, global health, sustainability and innovation, a key topic for #SynBioBeta2024.
Genomics and Sequencing
- Nanopore sequencing for cancer research: @nanopore demonstrates the comprehensive view their sequencing provides of variants in the cancer genome, capturing 189,900 bases in a single read with 1,658 insertions, 937 deletions, 248 SNVs, and 4,825 CpG methylations.
- PacBio HiFi sequencing for rare diseases: @PacBio shares a study integrating trait-relevant polygenic scores with their HiFi long-read whole genome sequencing to understand complex rare diseases.
- 10x Genomics solutions for cancer research: @10xGenomics scientists are excited to share their single cell & spatial advances to help unlock breakthroughs in cancer research at AACR 2024.
Longevity and Aging Research
- Earliest statement on aging: @ArtirKel found the oldest written statement of aging as a problem to be solved from Ptahhotep in 2300 BCE.
- Fighting aging: @realNathanCheng urges people to drop everything and fight aging after feeling bad and helpless about it.
- Aging research meeting: @biogerontology invites people to attend the @ARDD_Meeting focused on aging research and interventions.
Miscellaneous
- Vesper film and synbio: @Ginkgo announces a panel at their Ferment event with the directors and producers of the sci-fi film "Vesper" that explores the ethical dilemmas of synthetic biology.
- Biotech education report: @NikoMcCarty is preparing a final report after interviewing ~150 companies and visiting 50+ universities to build better biotech educational programs for undergrads.
- Illumina Connected Annotations: @illumina introduces a powerful genomic reference tool in Emedgene and DRAGEN to improve speed and accuracy of HGVS notations for researchers.