Starting with R installed from the download on the CRAN website.
install rpy2 from source using
python setup.py build install
running the unit test gives
python -m rpy2.tests
Traceback (most recent call last):
File "/Users/nickgravish/anaconda/lib/python3.5/runpy.py", line 170, in _run_module_as_main
"__main__", mod_spec)
File "/Users/nickgravish/anaconda/lib/python3.5/runpy.py", line 85, in _run_code
exec(code, run_globals)
File "/Users/nickgravish/anaconda/lib/python3.5/site-packages/rpy2-2.7.6-py3.5-macosx-10.5-x86_64.egg/rpy2/tests.py", line 23, in <module>
import rpy2.tests_rpy_classic
File "/Users/nickgravish/anaconda/lib/python3.5/site-packages/rpy2-2.7.6-py3.5-macosx-10.5-x86_64.egg/rpy2/tests_rpy_classic.py", line 3, in <module>
import rpy2.rpy_classic as rpy
File "/Users/nickgravish/anaconda/lib/python3.5/site-packages/rpy2-2.7.6-py3.5-macosx-10.5-x86_64.egg/rpy2/rpy_classic.py", line 5, in <module>
import rpy2.rinterface as ri
File "/Users/nickgravish/anaconda/lib/python3.5/site-packages/rpy2-2.7.6-py3.5-macosx-10.5-x86_64.egg/rpy2/rinterface/__init__.py", line 99, in <module>
from rpy2.rinterface._rinterface import *
ImportError: dlopen(/Users/nickgravish/anaconda/lib/python3.5/site-packages/rpy2-2.7.6-py3.5-macosx-10.5-x86_64.egg/rpy2/rinterface/_rinterface.cpython-35m-darwin.so, 2): Library not loaded: @rpath/R/lib/libR.dylib
Referenced from: /Users/nickgravish/anaconda/lib/python3.5/site-packages/rpy2-2.7.6-py3.5-macosx-10.5-x86_64.egg/rpy2/rinterface/_rinterface.cpython-35m-darwin.so
Reason: image not found
From this SO http://stackoverflow.com/questions/34421680/rpy2-rpath-issue-on-os-x-10-7
install_name_tool -change @rpath/R/lib/libR.dylib /Library/Frameworks/R.framework/Versions/3.2/Resources/lib/libR.dylib _rinterface.cpython-35m-darwin.so
install_name_tool -change @rpath/R/lib/libR.dylib /Library/Frameworks/R.framework/Versions/3.2/Resources/lib/libR.dylib _rpy_device.cpython-35m-darwin.so
These two commands fixed the unit test so that everything worked.