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January 10, 2023 18:21
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sample code for running BOLTLmm
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BOLT-LMM_v2.3.2/bolt \ | |
--bed=pca/UKB_tinnitus_eur_unrelated_{1..22}.bed \ | |
--bim=pca/UKB_tinnitus_eur_unrelated_{1..22}.bim \ | |
--fam=pca/UKB_tinnitus_eur_unrelated_1.fam \ | |
--LDscoresFile=BOLT-LMM_v2.3.2/tables/LDSCORE.1000G_EUR.tab.gz \ | |
--geneticMapFile=BOLT-LMM_v2.3.2/tables/genetic_map_hg19_withX.txt.gz \ | |
--lmmForceNonInf \ | |
--numThreads=6 \ | |
--bgenFile=/mnt/ukbb/adam/bgen/ukb_imp_chr{1..22}_v3.bgen \ | |
--bgenMinMAF=1e-3 \ | |
--bgenMinINFO=0.3 \ | |
--sampleFile=ukb40951_imp_chr1_v3_s487324.sample \ | |
--verboseStats \ | |
--modelSnps all.pruned \ | |
--remove bolt.in_plink_but_not_imputed.FID_IID.968.txt \ | |
--noBgenIDcheck \ | |
--statsFile=f.4803.max_coding1_allcov_unrelated.bed.stats.gz \ | |
--statsFileBgenSnps=zf.4803.max_coding1_allcov_unrelated.bgen.stats.gz \ | |
--phenoFile=UKB_tinnitus_eur_unrelated_april2_2019.pheno \ | |
--phenoCol=f.4803.max_coding1 \ | |
--covarFile=UKB_tinnitus_eur_unrelated_april2_2019.pheno \ | |
--qCovarCol=f.2247.max_coding1 --qCovarCol=f.21003.max --qCovarCol=f.31.0.0 --qCovarCol=f.22009.0.{1:6} --covarCol=f.54.0.0 --covarCol=f.22000.0.0 \ | |
--covarMaxLevels=107 | |
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