example.py

import os
import sys
sys.path.append(os.getcwd())

import clr
clr.AddReference('wpf\PresentationFramework') 
from System.IO import StreamReader
from System.Threading import ApartmentState, Thread, ThreadStart
from System.Windows import Application, LogicalTreeHelper, Window
from System.Windows.Markup import XamlReader

from System.Windows.Controls import *
clr.AddReference('System.Collections')
from System.Collections.Generic import *
from System.Windows.Data import Binding

class MyWindow(Window):
    def __init__(self):
        stream = StreamReader('example.xaml')
        window = XamlReader.Load(stream.BaseStream)

        TestDataGrid = LogicalTreeHelper.FindLogicalNode(window, "TestDataGrid")

        col1 = DataGridTextColumn()
        col1.Header = "Name"
        col1.Binding = Binding("name")
        TestDataGrid.Columns.Add(col1)
        names = List[str]()
        names.Add("Sam")
        names.Add("Carla")
        TestDataGrid.ItemsSource = names
        Application().Run(window)  


if __name__ == '__main__':
    thread = Thread(ThreadStart(MyWindow))
    thread.SetApartmentState(ApartmentState.STA)
    thread.Start()
    thread.Join()