scrape.js

var request = require('request')
  , cheerio = require('cheerio')
  , vm      = require('vm')
  , util    = require('util')
  , sandbox = {};

request({
  uri:'http://account.hirezstudios.com/smitegame/items.aspx',
  headers:{
    'User-Agent': 'Mozilla/5.0 (Macintosh; Intel Mac OS X 10_9_0) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/31.0.1650.63 Safari/537.36'
  }
}, function(err, response, body){
  if (err) return;
  // load html into cheerio
  var $ = cheerio.load(body);
  // find script that contains your json
  // split on semicolons to separate json
  var scripts = $('script:contains("jsonItems")').text().split(';');

  // run the script in the context of sandbox
  vm.runInNewContext(scripts[0], sandbox)

  var data = JSON.parse(sandbox.jsonItems);

  // mess with data here
  console.log(util.inspect(data, false, 2, true));
})