Python + OS X bash_profile...

bash_profile

if [ -d "${HOME}/Library/Python/2.7" ]; then
  export PATH="${PATH}:${HOME}/Library/Python/2.7/bin"
fi

function frameworkpython {
  if [[ ! -z "$VIRTUAL_ENV" ]]; then
    PYTHONHOME=$VIRTUAL_ENV /usr/bin/python "$@"
  else
    /usr/bin/python "$@"
  fi
}

function jupyter {
  jcmd=$1
  shift

  if [[ ! -z "$VIRTUAL_ENV" ]]; then
    jupyter_prefix="${VIRTUAL_ENV}/bin/jupyter"
  else
    jupyter_prefix="$(which jupyter)"
  fi

  if [[ -z "${jupyter_prefix}" ]]; then
    echo "Could not find Jupyter in your path"
    exit 1
  fi

  frameworkpython "${jupyter_prefix}-${jcmd}" "$@"
}