http://philgr.com/blog/search-in-apps-with-custom-bangs

BangSearch.py

from webbrowser import open
from urllib import quote

query = sys.argv[1]

#Web Services
stackoverflow = '!s '
wikipedia = '!w '
macupdate = '!mac '
appshopper = '!app '
imdb = '!imdb '
amazon = '!amaz '
wolframalpha = '!wolf '
reddit = '!red '
alternativeto = '!to '
hackernews = '!hack '
merriamwebster = '!def '

#Apps
onepassword = '!op '
wikipanion = '!wiki '
tweetbot = '!tb '
terminology = '!te '
imdbapp = '!movie '
articles = '!art '
twitterrific = '!twi '
rdio = '!rd '
fantastical = '!day '
due = '!due '
wolframapp = '!wol '
appstore = '!store '


if stackoverflow in query:  
    open('safari-http://stackoverflow.com/search?q=' + quote(query.replace(stackoverflow,''))) #Stack Overflow
elif wikipedia in query:
    open('safari-https://en.wikipedia.org/w/index.php?search=' + quote(query.replace(wikipedia,'')) + '&title=Special%3ASearch') #Wikipedia
elif macupdate in query:
    open('safari-https://www.macupdate.com/find/mac/' + quote(query.replace(macupdate,''))) #MacUpdate
elif appshopper in query:
    open('safari-http://appshopper.com/search/?search=' + quote(query.replace(appshopper,''))) #AppShopper
elif imdb in query:
    open('safari-http://www.imdb.com/find?q=' + quote(query.replace(imdb,'')) + '&s=all') #IMDB
elif amazon in query:
    open('safari-http://www.amazon.com/s/ref=nb_sb_noss?url=search-alias%3Daps&field-keywords=' + quote(query.replace(amazon,''))) #Amazon
elif wolframalpha in query:
    open('safari-http://www.wolframalpha.com/input/?i=' + quote(query.replace(wolframalpha,''))) #Wolfram|Alpha
elif reddit in query:
    open('safari-http://www.reddit.com/r/search/search?q=' + quote(query.replace(reddit,''))) #Reddit
elif alternativeto in query:
    open('safari-http://alternativeto.net/SearchResult.aspx?search=' + quote(query.replace(alternativeto,''))) #AlternativeTo
elif hackernews in query:
    open('safari-https://www.hnsearch.com/search#request/all&q=' + quote(query.replace(hackernews,'')) + '&start=0') #Hacker News
elif merriamwebster in query:
    open('safari-http://www.merriam-webster.com/dictionary/' + quote(query.replace(merriamwebster,''))) #Merriam-Webster
elif onepassword in query:
    open('onepassword://search/' + quote(query.replace(onepassword,''))) #1Password
elif wikipanion in query:
    open('wikipanion:///' + quote(query.replace(wikipanion,''))) #Wikipanion
elif tweetbot in query:
    open('tweetbot:///search?query=' + quote(query.replace(tweetbot,''))) #Tweetbot
elif terminology in query:
    open('terminology://x-callback-url/lookup?text=' + quote(query.replace(terminology,''))) #Terminology
elif imdbapp in query:
    open('imdb:///find?q=' + quote(query.replace(imdbapp,''))) #IMDB app
elif articles in query:
    open('x-articles://?search=' + quote(query.replace(articles,''))) #Articles
elif twitterrific in query:
    open('twitterrific:///search?q=' + quote(query.replace(twitterrific,''))) #Twitterrific
elif rdio in query:
    open('rdio://search/' + quote(query.replace(rdio,''))) #Rdio
elif fantastical in query:
    open('fantastical://search?query=' + quote(query.replace(fantastical,''))) #Fantastical
elif due in query:
    open('due://x-callback-url/search?query=' + quote(query.replace(due,''))) #Due
elif wolframapp in query:
    open('wolframalpha:///?i=' + quote(query.replace(wolframapp,''))) #Wolfram|Alpha app
elif appstore in query:
    open('http://phobos.apple.com/WebObjects/MZSearch.woa/wa/search?media=software&term=' + quote(query.replace(appstore,''))) #AppStore
else:
    open('safari-https://duckduckgo.com/?q=' + quote(query)) #Falls back on DuckDuckGo